Table 1.6.4
Proposed environmental triggers for endocrine autoimmune diseases subdivided by how they may trigger autoimmunity
Proposed environmental factor Endocrine autoimmune disease linked with environmental factor

Fetal/maternal environment

Maternal medicine during pregnancy

Type 1 diabetes

Maternal age, excessive weight gain during pregnancy

Type 1 diabetes

Birth by caesarean section

Type 1 diabetes

Introduction of foreign particles into the body

Chemicals – nitrates, nitrites, pesticides and industrial chemicals

GD, HT, type 1 diabetes

Viruses and bacteria

GD, HT, type 1 diabetes

Dietary factors – cereals, gluten

Type 1 diabetes

Cow’s milk

Type 1 diabetes

Eczema

Type 1 diabetes

Growing up in the city versus the country

Type 1 diabetes

Iodine levels

GD, HT

Altering how the immune system functions

Vitamin D levels

Type 1 diabetes

Smoking or passive smoking

GD, HT, type 1 diabetes

Stressful life events

GD, HT, type 1 diabetes

Excessive weight

Type 1 diabetes

Proposed environmental factor Endocrine autoimmune disease linked with environmental factor

Fetal/maternal environment

Maternal medicine during pregnancy

Type 1 diabetes

Maternal age, excessive weight gain during pregnancy

Type 1 diabetes

Birth by caesarean section

Type 1 diabetes

Introduction of foreign particles into the body

Chemicals – nitrates, nitrites, pesticides and industrial chemicals

GD, HT, type 1 diabetes

Viruses and bacteria

GD, HT, type 1 diabetes

Dietary factors – cereals, gluten

Type 1 diabetes

Cow’s milk

Type 1 diabetes

Eczema

Type 1 diabetes

Growing up in the city versus the country

Type 1 diabetes

Iodine levels

GD, HT

Altering how the immune system functions

Vitamin D levels

Type 1 diabetes

Smoking or passive smoking

GD, HT, type 1 diabetes

Stressful life events

GD, HT, type 1 diabetes

Excessive weight

Type 1 diabetes

GD, Graves’ disease; HT, Hashimoto’s thyroiditis.

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