Table 3.3.11.1
Treatment of toxic multinodular goitre and toxic adenoma
Modality Advantages Disadvantages

Surgery

Effective

Simple operation

Rapid euthyroidism

Hospitalization

Anaesthesia

Side effects (vocal cord paralysis, hypoparathyroidism)

Radio-iodine therapy

Outpatient therapy

Time to cure

Possible hypothyroidism in the long term

Antithyroid drugs

Rapid euthyroidism

Not destructive

Relapse on stopping

Side effects (skin, liver, bone marrow)

Percutaneous ethanol treatment

Outpatient procedure

Effective

Limited long-term experience

Several treatment sessions required

Side effects (vocal cord paralysis, pain)

Modality Advantages Disadvantages

Surgery

Effective

Simple operation

Rapid euthyroidism

Hospitalization

Anaesthesia

Side effects (vocal cord paralysis, hypoparathyroidism)

Radio-iodine therapy

Outpatient therapy

Time to cure

Possible hypothyroidism in the long term

Antithyroid drugs

Rapid euthyroidism

Not destructive

Relapse on stopping

Side effects (skin, liver, bone marrow)

Percutaneous ethanol treatment

Outpatient procedure

Effective

Limited long-term experience

Several treatment sessions required

Side effects (vocal cord paralysis, pain)

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