Table 4.3.3
A comparison of new and old guidelines for surgery in asymptomatic primary hyperparathyroidism
Measurement Guidelines 1990 Guidelines 2002 Guidelines 2008

Serum calcium (above normal)

1–1.6 mg/dl

1.0 mg/dl

1.0 mg/dl

24-h urinary calcium

>400 mg

>400 mg

Creatinine clearance

Reduced by 30%

Reduced by 30%

< 60 cc/min

Bone mineral density

Z-score < −2.0 (forearm)

T-score < −2.5 (any site)

T-score < −2.5/ fragility fracture

Age

50

50

50

Measurement Guidelines 1990 Guidelines 2002 Guidelines 2008

Serum calcium (above normal)

1–1.6 mg/dl

1.0 mg/dl

1.0 mg/dl

24-h urinary calcium

>400 mg

>400 mg

Creatinine clearance

Reduced by 30%

Reduced by 30%

< 60 cc/min

Bone mineral density

Z-score < −2.0 (forearm)

T-score < −2.5 (any site)

T-score < −2.5/ fragility fracture

Age

50

50

50

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