Supplementary Table 8. Open in new tab...

	Original analysis			Sensitivity analysis
Treatment duration (months)	7	MD: –0.55 (–3.73, 2.63)	0.73	2	MD: 2.69 (–4.97, 10.35)	0.49
ABO-OGS total score	2	MD: 13.38 (9.45, 17.31)	<0.001^†	0	-
ABO-OGS failure (score>30)	2	RR: 1.63 (1.24, 2.13)	<0.001^†	0	-
ABO-OGS component: alignment	2	MD: 2.60 (–0.48, 5.69)	0.10	0	-
ABO-OGS component: marginal ridges	2	MD: 0.60 (–0.22, 1.43)	0.15	0	-
ABO-OGS component: buccolingual inclination	2	MD: 1.14 (0.21, 2.07)	0.02^†	0	-
ABO-OGS component: occlusal contacts	2	MD: 4.45 (2.72, 6.18)	<0.001^†	0	-
ABO-OGS component: occlusal relationship	2	MD: 1.39 (–0.12, 2.89)	0.07	0	-
ABO-OGS component: overjet	2	MD: 2.61 (1.29, 3.93)	<0.001^†	0	-
ABO-OGS component: interproximal contacts	2	MD: 0.02 (–0.17, 0.21)	0.83	0	-
ABO-OGS component: root angulation	2	MD: 0.87 (0.46, 1.28)	<0.001^†	0	-
PAR post-Tx	2	MD: –0.03 (–2.02, 1.96)	0.98	0	-
PAR reduction via Tx	3	MD: –1.76 (–3.62, 0.10)	0.06	0	-

Original analysis

Sensitivity analysis

Outcome

Effect (95% CI)

Treatment duration (months)

MD: –0.55 (–3.73, 2.63)

0.73

MD: 2.69 (–4.97, 10.35)

0.49

ABO-OGS total score

MD: 13.38 (9.45, 17.31)

<0.001^†

ABO-OGS failure (score>30)

RR: 1.63 (1.24, 2.13)

<0.001^†

ABO-OGS component: alignment

MD: 2.60 (–0.48, 5.69)

0.10

ABO-OGS component: marginal ridges

MD: 0.60 (–0.22, 1.43)

0.15

ABO-OGS component: buccolingual inclination

MD: 1.14 (0.21, 2.07)

0.02^†

ABO-OGS component: occlusal contacts

MD: 4.45 (2.72, 6.18)

<0.001^†

ABO-OGS component: occlusal relationship

MD: 1.39 (–0.12, 2.89)

0.07

ABO-OGS component: overjet

MD: 2.61 (1.29, 3.93)

<0.001^†

ABO-OGS component: interproximal contacts

MD: 0.02 (–0.17, 0.21)

0.83

ABO-OGS component: root angulation

MD: 0.87 (0.46, 1.28)

<0.001^†

PAR post-Tx

MD: –0.03 (–2.02, 1.96)

0.98

PAR reduction via Tx

MD: –1.76 (–3.62, 0.10)

0.06

	Original analysis			Sensitivity analysis
Treatment duration (months)	7	MD: –0.55 (–3.73, 2.63)	0.73	2	MD: 2.69 (–4.97, 10.35)	0.49
ABO-OGS total score	2	MD: 13.38 (9.45, 17.31)	<0.001^†	0	-
ABO-OGS failure (score>30)	2	RR: 1.63 (1.24, 2.13)	<0.001^†	0	-
ABO-OGS component: alignment	2	MD: 2.60 (–0.48, 5.69)	0.10	0	-
ABO-OGS component: marginal ridges	2	MD: 0.60 (–0.22, 1.43)	0.15	0	-
ABO-OGS component: buccolingual inclination	2	MD: 1.14 (0.21, 2.07)	0.02^†	0	-
ABO-OGS component: occlusal contacts	2	MD: 4.45 (2.72, 6.18)	<0.001^†	0	-
ABO-OGS component: occlusal relationship	2	MD: 1.39 (–0.12, 2.89)	0.07	0	-
ABO-OGS component: overjet	2	MD: 2.61 (1.29, 3.93)	<0.001^†	0	-
ABO-OGS component: interproximal contacts	2	MD: 0.02 (–0.17, 0.21)	0.83	0	-
ABO-OGS component: root angulation	2	MD: 0.87 (0.46, 1.28)	<0.001^†	0	-
PAR post-Tx	2	MD: –0.03 (–2.02, 1.96)	0.98	0	-
PAR reduction via Tx	3	MD: –1.76 (–3.62, 0.10)	0.06	0	-

Supplementary Table 8.

Open in new tab

Sensitivity analysis by omitting non-randomized studies (without the Li et al., 2015 study).

	Original analysis			Sensitivity analysis
Outcome	n	Effect (95% CI)	P	n	Effect (95% CI)	P
Treatment duration (months)	7	MD: –0.55 (–3.73, 2.63)	0.73	2	MD: 2.69 (–4.97, 10.35)	0.49
ABO-OGS total score	2	MD: 13.38 (9.45, 17.31)	<0.001^†	0	-
ABO-OGS failure (score>30)	2	RR: 1.63 (1.24, 2.13)	<0.001^†	0	-
ABO-OGS component: alignment	2	MD: 2.60 (–0.48, 5.69)	0.10	0	-
ABO-OGS component: marginal ridges	2	MD: 0.60 (–0.22, 1.43)	0.15	0	-
ABO-OGS component: buccolingual inclination	2	MD: 1.14 (0.21, 2.07)	0.02^†	0	-
ABO-OGS component: occlusal contacts	2	MD: 4.45 (2.72, 6.18)	<0.001^†	0	-
ABO-OGS component: occlusal relationship	2	MD: 1.39 (–0.12, 2.89)	0.07	0	-
ABO-OGS component: overjet	2	MD: 2.61 (1.29, 3.93)	<0.001^†	0	-
ABO-OGS component: interproximal contacts	2	MD: 0.02 (–0.17, 0.21)	0.83	0	-
ABO-OGS component: root angulation	2	MD: 0.87 (0.46, 1.28)	<0.001^†	0	-
PAR post-Tx	2	MD: –0.03 (–2.02, 1.96)	0.98	0	-
PAR reduction via Tx	3	MD: –1.76 (–3.62, 0.10)	0.06	0	-

	Original analysis			Sensitivity analysis
Outcome	n	Effect (95% CI)	P	n	Effect (95% CI)	P
Treatment duration (months)	7	MD: –0.55 (–3.73, 2.63)	0.73	2	MD: 2.69 (–4.97, 10.35)	0.49
ABO-OGS total score	2	MD: 13.38 (9.45, 17.31)	<0.001^†	0	-
ABO-OGS failure (score>30)	2	RR: 1.63 (1.24, 2.13)	<0.001^†	0	-
ABO-OGS component: alignment	2	MD: 2.60 (–0.48, 5.69)	0.10	0	-
ABO-OGS component: marginal ridges	2	MD: 0.60 (–0.22, 1.43)	0.15	0	-
ABO-OGS component: buccolingual inclination	2	MD: 1.14 (0.21, 2.07)	0.02^†	0	-
ABO-OGS component: occlusal contacts	2	MD: 4.45 (2.72, 6.18)	<0.001^†	0	-
ABO-OGS component: occlusal relationship	2	MD: 1.39 (–0.12, 2.89)	0.07	0	-
ABO-OGS component: overjet	2	MD: 2.61 (1.29, 3.93)	<0.001^†	0	-
ABO-OGS component: interproximal contacts	2	MD: 0.02 (–0.17, 0.21)	0.83	0	-
ABO-OGS component: root angulation	2	MD: 0.87 (0.46, 1.28)	<0.001^†	0	-
PAR post-Tx	2	MD: –0.03 (–2.02, 1.96)	0.98	0	-
PAR reduction via Tx	3	MD: –1.76 (–3.62, 0.10)	0.06	0	-

ABO-OGS, objective grading system of the American Board of Orthodontics; CI, confidence interval; MD, mean difference; PAR, peer assessment rating; RR, relative risk; Tx, treatment.

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