Table 46.3 Open in new tab Physical... | Oxford Academic

Table 46.3

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Physical characteristics and key features of the complete nuclear genomes for Cryptosporidium parvum (see Abrahamsen et al. 2004) and Cryptosporidium hominis (see Xu et al. 2004)

Nuclear Genomes
	C. parvum	C. hominis
Size (Mbp)	∼ 9.1	∼ 9.2
Genes	∼ 4,000	∼ 4,000
Introns (%)	∼ 5%	∼ 5-20%
Non-coding (%)	∼ 25–30%	∼ 25–30%
Key features
No organellar genomes.
ATP production heavily reliant upon glycolysis.
Scavenges amino acids from host (limited or no amino acid synthesis pathways).
Has enzymes necessary to convert from one amino acid to another.
Scavenges nucleotides from the host (limited or no nucleotide synthesis pathways).
Can convert purines to pyrimidines and vice versa.
Has a single enzyme (inosine monophosphate dehydrogenase) for converting AMP to GMP.

Nuclear Genomes
	C. parvum	C. hominis
Size (Mbp)	∼ 9.1	∼ 9.2
Genes	∼ 4,000	∼ 4,000
Introns (%)	∼ 5%	∼ 5-20%
Non-coding (%)	∼ 25–30%	∼ 25–30%
Key features
No organellar genomes.
ATP production heavily reliant upon glycolysis.
Scavenges amino acids from host (limited or no amino acid synthesis pathways).
Has enzymes necessary to convert from one amino acid to another.
Scavenges nucleotides from the host (limited or no nucleotide synthesis pathways).
Can convert purines to pyrimidines and vice versa.
Has a single enzyme (inosine monophosphate dehydrogenase) for converting AMP to GMP.