Benzylpenicillin

1.2g 6‐hourly (2‐hourly for pneumococcal pneumonia)

Flucloxacillin

500mg–2g 6‐hourly

Ampicillin

500mg–1g 6‐hourly

Piptazobactam

4.5g 6–8 hourly

Ceftazidime

2g 8‐hourly

Ceftriaxone

1–4g daily

Cefuroxime

750mg–1.5g 8‐hourly

Gentamicin

1.5mg/kg stat, then by levels (usually 80mg 8‐hourly)

Amikacin

7.5mg/kg stat, then by levels (usually 500mg 12‐hourly)

Tobramycin

5mg/kg stat, then by levels (usually 100mg 8‐hourly)

Erythromycin

500mg–1g 6–12hourly

Metronidazole

500mg 8‐hourly or 1g 12‐hourly PR

Clindamycin

300–600mg 6‐hourly

Ciprofloxacin

200–400mg 12‐hourly

Co‐trimoxazole

960mg 12‐hourly in Pneumocystis carinii pneumonia

Tigecycline

100mg initially, then 50mg 12‐hourly

Imipenem

1–2g 6–8 hourly

Meropenem

500mg–1g 8‐hourly

Rifampicin

600mg daily

Teicoplanin

400mg 12‐hourly for 3 doses, then 400mg daily

Vancomycin

500mg 6‐hourly (monitor levels)

Linezolid

600mg 12‐hourly

Chloramphenicol

1–2g 6‐hourly

Amphotericin

250mcg–1mg/kg daily

Flucytosine

25–50mg/kg 6‐hourly

Fluconazole

200–400mg daily

Caspofungin

70mg stat, then 50–70mg daily

Voriconazole

400mg 12‐hourly on first day, then 200–300mg 12‐hourly

Itraconazole

200mg 12‐hourly for 2 days, then 200mg daily

Aciclovir

10mg/kg 8‐hourly

Ganciclovir

5mg/kg 12‐hourly