Dose Equivalence for Transdermal Fentanyl (Durogesic ®DTrans ®) and Oral Morphine
24 hourly Oral Morphine Dose (mg) Fentanyl Patch Strength (mcg/hr) 4 Hourly Oral Morphine (mg) (also breakthrough medication dose)

<90

25

<15

90–134

37

15–20

135–189

50

25–30

190–224

62

35

225–314

75

40–50

315–404

100

55–65

405–494

125

70–80

495–584

150

85–95

585–674

175

100–110

675–764

200

115–125

765–854

225

130–140

855–944

250

145–155

945–1034

275

160–170

1035–1124

300

175–185

24 hourly Oral Morphine Dose (mg) Fentanyl Patch Strength (mcg/hr) 4 Hourly Oral Morphine (mg) (also breakthrough medication dose)

<90

25

<15

90–134

37

15–20

135–189

50

25–30

190–224

62

35

225–314

75

40–50

315–404

100

55–65

405–494

125

70–80

495–584

150

85–95

585–674

175

100–110

675–764

200

115–125

765–854

225

130–140

855–944

250

145–155

945–1034

275

160–170

1035–1124

300

175–185

Please note conversion factors may change depending on direction of conversionNOTE: Transdermal Fentanyl Patch has 72 hour duration of action i.e. changed every 3 days

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