| Conversion factors for guidance when converting from one opioid to another . |
|---|
Oral Morphine to Subcutaneous (SC) Diamorphine – Divide by 3 Eg 30 mg Oral Morphine = 10 mg SC Diamorphine |
Oral Morphine to Oral Oxycodone – Divide by 2 Eg 30 mg Oral Morphine = 15 mg Oral Oxycodone |
Oral Morphine to Subcutaneous Morphine – Divide by 2 Eg 30 mg Oral Morphine = 15 mg SC Morphine |
Oral Morphine to Oral Hydromorphone – Divide by 7.5 Eg 30 mg Oral Morphine = 4 mg Oral Hydromorphone |
Oral Oxycodone to SC Oxycodone – Divide by 2 (Suggested safe practice) Eg 10 mg Oral Oxycodone = 5 mg SC Oxycodone |
Oral Hydromorphone to SC Hydromorphone – Divide by 2 Eg 4 mg Oral Hydromorphone = 2 mg SC Hydromorphone |
SC Diamorphine to SC Oxycodone – Treat as equivalent up to doses of 60 mg/24 hrs Caution should be used when converting higher doses (Suggested safe practice) Eg 10 mg SC Diamorphine = 10 mg SC Oxycodone |
SC Diamorphine to SC Alfentanil – Divide by 10 Eg 10 mg SC Diamorphine = 1 mg SC Alfentanil |
SC Diamorphine to SC Morphine – ratio is between 1:1.5 and 1:2 – Multiply by 1.5 Eg 10 mg SC Diamorphine = 15 mg SC Morphine |
Oral Tramadol to Oral Morphine– Divide by 10 (Suggested safe practice)* Eg 100 mg Oral Tramadol = 10 mg Oral Morphine |
Oral Codeine / Dihydrocodeine to Oral Morphine – Divide by 10 Eg 240 mg Oral Codeine / Dihydrocodeine = 24 mg Oral Morphine |
| Conversion factors for guidance when converting from one opioid to another . |
|---|
Oral Morphine to Subcutaneous (SC) Diamorphine – Divide by 3 Eg 30 mg Oral Morphine = 10 mg SC Diamorphine |
Oral Morphine to Oral Oxycodone – Divide by 2 Eg 30 mg Oral Morphine = 15 mg Oral Oxycodone |
Oral Morphine to Subcutaneous Morphine – Divide by 2 Eg 30 mg Oral Morphine = 15 mg SC Morphine |
Oral Morphine to Oral Hydromorphone – Divide by 7.5 Eg 30 mg Oral Morphine = 4 mg Oral Hydromorphone |
Oral Oxycodone to SC Oxycodone – Divide by 2 (Suggested safe practice) Eg 10 mg Oral Oxycodone = 5 mg SC Oxycodone |
Oral Hydromorphone to SC Hydromorphone – Divide by 2 Eg 4 mg Oral Hydromorphone = 2 mg SC Hydromorphone |
SC Diamorphine to SC Oxycodone – Treat as equivalent up to doses of 60 mg/24 hrs Caution should be used when converting higher doses (Suggested safe practice) Eg 10 mg SC Diamorphine = 10 mg SC Oxycodone |
SC Diamorphine to SC Alfentanil – Divide by 10 Eg 10 mg SC Diamorphine = 1 mg SC Alfentanil |
SC Diamorphine to SC Morphine – ratio is between 1:1.5 and 1:2 – Multiply by 1.5 Eg 10 mg SC Diamorphine = 15 mg SC Morphine |
Oral Tramadol to Oral Morphine– Divide by 10 (Suggested safe practice)* Eg 100 mg Oral Tramadol = 10 mg Oral Morphine |
Oral Codeine / Dihydrocodeine to Oral Morphine – Divide by 10 Eg 240 mg Oral Codeine / Dihydrocodeine = 24 mg Oral Morphine |
Limited evidence suggests that, when converting from Oral Tramadol to Oral Morphine, the dose should be divided by 5. However this may result in too high a dose for some patients hence locally agreed suggested safe practice is to divide by 10 and ensure appropriate breakthrough dose is available.
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