Table 6a.19
Comparison of the most frequently used local anaesthetics for spinal use
Lidocaine Bupivacaine Ropivacaine

Onset

Rapid

Slower

Similar to bupivacaine

Duration

Short (hours)

2–3 times longer than lidocaine

Slightly longer than bupivacaine

Typical dosage

2mL 2% over 24h

2mL 0.5% over 24h

2mL 0.75% over 24h

Advantages

Rapid onset and off-set

Synergism with opioids

May preferentially block sensory nerves

Synergism with opioids

Two-thirds as potent as bupivacaine

Synergism with opioids

Lidocaine Bupivacaine Ropivacaine

Onset

Rapid

Slower

Similar to bupivacaine

Duration

Short (hours)

2–3 times longer than lidocaine

Slightly longer than bupivacaine

Typical dosage

2mL 2% over 24h

2mL 0.5% over 24h

2mL 0.75% over 24h

Advantages

Rapid onset and off-set

Synergism with opioids

May preferentially block sensory nerves

Synergism with opioids

Two-thirds as potent as bupivacaine

Synergism with opioids

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