Table 12.3
PM/DM-associated antibodies and corresponding target antigens
Anti-synthetase syndrome antibodiesTarget antigen

Anti-Jo-1 (25%)

Histidyl-tRNA synthetase

Anti-PL-7 (rare)

Threonyl-tRNA synthetase

Anti-PL12 (rare)

Alanyl-tRNA synthetase

Anti-OJ (rare)

Isoleucyl-tRNA synthetase

Anti-EJ (rare)

Glycyl-tRNA synthetases

Anti-KS (rare)

Asparaginyl-tRNA synthetase

Anti-Zo (rare)

Phenylalanyl-tRNA synthetase

Anti-synthetase syndrome antibodiesTarget antigen

Anti-Jo-1 (25%)

Histidyl-tRNA synthetase

Anti-PL-7 (rare)

Threonyl-tRNA synthetase

Anti-PL12 (rare)

Alanyl-tRNA synthetase

Anti-OJ (rare)

Isoleucyl-tRNA synthetase

Anti-EJ (rare)

Glycyl-tRNA synthetases

Anti-KS (rare)

Asparaginyl-tRNA synthetase

Anti-Zo (rare)

Phenylalanyl-tRNA synthetase

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