Table 23.3
Results from cardiopulmonary exercise testing in patients with differential diagnoses
VariableChronic heart failureChronic obstructive airways diseaseObesityHyperventilationPoor effort

pVo2

AT

↔/↓

Often impossible to determine or normal

RER at peak

↓ at peak

Ve/Vco2

↑/↔

↑/↔

↑/↔

Breathing reserve

↔/↑

Vital capacity

P  et  co  2

Comments

Reduced ΔVo2/ΔWR, oscillatory breathing

Increased dead space, FEV1 low

Physical examination confirms obesity

RER and ventilation ↑ prior to exercise, abrupt further increase in ventilation at onset of exercise

VariableChronic heart failureChronic obstructive airways diseaseObesityHyperventilationPoor effort

pVo2

AT

↔/↓

Often impossible to determine or normal

RER at peak

↓ at peak

Ve/Vco2

↑/↔

↑/↔

↑/↔

Breathing reserve

↔/↑

Vital capacity

P  et  co  2

Comments

Reduced ΔVo2/ΔWR, oscillatory breathing

Increased dead space, FEV1 low

Physical examination confirms obesity

RER and ventilation ↑ prior to exercise, abrupt further increase in ventilation at onset of exercise

pVo2; peak O2 consumption, RER; respiratory exchange ratio, Ve/Vco2; relationship between ventilation and CO2 production, Petco2; end-tidal CO2, ΔVo2/ΔWR; ratio between change in O2 consumption and change in work rate

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