| UC . | Crohn’s . |
|---|---|
Toxic megacolon Colon distends and may perforate Colonic cancer Risk ↑ if disease >8y, onset in childhood/adolescence, age >45y, FH of colon cancer, extensive colitis, sclerosing cholangitis. Prevention: screening with colonoscopy Frequency depends on severity of the disease and duration of symptoms Sclerosing cholangitis Fibrosis and stricture of intra- and extrahepatic bile ducts. Presents with obstructive jaundice | Intra-abdominal abscess Intestinal stricture Common—may require surgery Toxic megacolon Rare (see UC) Bowel obstruction Fistula formation Perianal disease Malignancy Large and small bowel cancer—5% 10y after diagnosis Osteoporosis |
Psychological effects Chronic, life-long conditions which have major impact on work and domestic life. Self-help groups can be useful | |
| UC . | Crohn’s . |
|---|---|
Toxic megacolon Colon distends and may perforate Colonic cancer Risk ↑ if disease >8y, onset in childhood/adolescence, age >45y, FH of colon cancer, extensive colitis, sclerosing cholangitis. Prevention: screening with colonoscopy Frequency depends on severity of the disease and duration of symptoms Sclerosing cholangitis Fibrosis and stricture of intra- and extrahepatic bile ducts. Presents with obstructive jaundice | Intra-abdominal abscess Intestinal stricture Common—may require surgery Toxic megacolon Rare (see UC) Bowel obstruction Fistula formation Perianal disease Malignancy Large and small bowel cancer—5% 10y after diagnosis Osteoporosis |
Psychological effects Chronic, life-long conditions which have major impact on work and domestic life. Self-help groups can be useful | |
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