Table 15.10
Specific features of rheumatoid arthritis

Hands

Ulnar deviation of the fingers

‘z’ deformity of the thumb

Swan neck (hyperextended PIP and flexed DIP joints) and boutonnière (flexed PIP and extended MCP joints, hyperextended DIP joint) deformities of the fingers (see Figure 15.4)

↓ grip strength and ↓ hand function causes disability

Legs and feet

Subluxation of the metatarsal heads in feet and claw toes → pain on walking

Baker’s cysts (graphic p. 494) at the knee may rupture mimicking DVT

Spine

Especially cervical spine—causing neck pain, cervical subluxation, and atlanto-axial instability leading to a risk of cord compression. X-rays are required prior to general anaesthesia

Non-articular features

Common. Weight ↓, fever, malaise

Rheumatoid nodules (especially extensor surfaces of forearms)

Vasculitis—digital infarction, skin ulcers, mononeuritis

Eye—Sjögren’s syndrome, episcleritis, scleritits

Lungs—pleural effusions, fibrosing alveolitis, nodules

Heart—pericarditis, mitral valve disease, conduction defects

Skin—palmar erythema, vasculitis, rashes

Neurological—nerve entrapment, e.g. carpal tunnel syndrome, mononeuritis, and peripheral neuropathy

Felty’s syndrome Combination of RA, splenomegaly, and leucopenia. Occurs in patients with long-standing RA. Recurrent infections are common. Hypersplenism → anaemia and thrombocytopenia. Associated with lymphadenopathy, pigmentation, and persistent skin ulcers. Splenectomy may improve the neutropenia

Hands

Ulnar deviation of the fingers

‘z’ deformity of the thumb

Swan neck (hyperextended PIP and flexed DIP joints) and boutonnière (flexed PIP and extended MCP joints, hyperextended DIP joint) deformities of the fingers (see Figure 15.4)

↓ grip strength and ↓ hand function causes disability

Legs and feet

Subluxation of the metatarsal heads in feet and claw toes → pain on walking

Baker’s cysts (graphic p. 494) at the knee may rupture mimicking DVT

Spine

Especially cervical spine—causing neck pain, cervical subluxation, and atlanto-axial instability leading to a risk of cord compression. X-rays are required prior to general anaesthesia

Non-articular features

Common. Weight ↓, fever, malaise

Rheumatoid nodules (especially extensor surfaces of forearms)

Vasculitis—digital infarction, skin ulcers, mononeuritis

Eye—Sjögren’s syndrome, episcleritis, scleritits

Lungs—pleural effusions, fibrosing alveolitis, nodules

Heart—pericarditis, mitral valve disease, conduction defects

Skin—palmar erythema, vasculitis, rashes

Neurological—nerve entrapment, e.g. carpal tunnel syndrome, mononeuritis, and peripheral neuropathy

Felty’s syndrome Combination of RA, splenomegaly, and leucopenia. Occurs in patients with long-standing RA. Recurrent infections are common. Hypersplenism → anaemia and thrombocytopenia. Associated with lymphadenopathy, pigmentation, and persistent skin ulcers. Splenectomy may improve the neutropenia

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