Table 23.6
Treatment of tardive dyskinesia with tiapride
ReferenceNumber of patientsLength of treatmentDose
(mg/day)
Results

Buruma et al. (1982)

12

2 weeks

300

Significant effect

Murphy et al. (1982)

8

6 weeks

600–800

No significant effect

Rust (1983)

37

4 weeks to > 3 months

300–600

30 patients improved

Auberger et al. (1985)

21

12 weeks

600

Significant effect at weeks 6–8 of treatment

Pollak et al. (1985)

10

4 weeks

510 + 120

Three patients improved

Perenyi et al. (1985)

10

4 weeks

300–600

Reduced AIMS score, no significant effect

Leblhuber et al. (1987)

12

3 weeks

300

Significant effect

Diedrich and Müller (1989)

1

8 months

150

Complete improvement

ReferenceNumber of patientsLength of treatmentDose
(mg/day)
Results

Buruma et al. (1982)

12

2 weeks

300

Significant effect

Murphy et al. (1982)

8

6 weeks

600–800

No significant effect

Rust (1983)

37

4 weeks to > 3 months

300–600

30 patients improved

Auberger et al. (1985)

21

12 weeks

600

Significant effect at weeks 6–8 of treatment

Pollak et al. (1985)

10

4 weeks

510 + 120

Three patients improved

Perenyi et al. (1985)

10

4 weeks

300–600

Reduced AIMS score, no significant effect

Leblhuber et al. (1987)

12

3 weeks

300

Significant effect

Diedrich and Müller (1989)

1

8 months

150

Complete improvement

Reproduced with permission from Ebel H. Therapy of neuroleptic-induced extrapyramidal movement disorders. Neurol Psych Brain Res 1994; 2:140–151. © Elsevier.

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