Reference . | Number of patients . | Length of treatment . | Dose (mg/day) . | Results . |
---|---|---|---|---|
Buruma et al. (1982) | 12 | 2 weeks | 300 | Significant effect |
Murphy et al. (1982) | 8 | 6 weeks | 600–800 | No significant effect |
Rust (1983) | 37 | 4 weeks to > 3 months | 300–600 | 30 patients improved |
Auberger et al. (1985) | 21 | 12 weeks | 600 | Significant effect at weeks 6–8 of treatment |
Pollak et al. (1985) | 10 | 4 weeks | 510 + 120 | Three patients improved |
Perenyi et al. (1985) | 10 | 4 weeks | 300–600 | Reduced AIMS score, no significant effect |
Leblhuber et al. (1987) | 12 | 3 weeks | 300 | Significant effect |
Diedrich and Müller (1989) | 1 | 8 months | 150 | Complete improvement |
Reference . | Number of patients . | Length of treatment . | Dose (mg/day) . | Results . |
---|---|---|---|---|
Buruma et al. (1982) | 12 | 2 weeks | 300 | Significant effect |
Murphy et al. (1982) | 8 | 6 weeks | 600–800 | No significant effect |
Rust (1983) | 37 | 4 weeks to > 3 months | 300–600 | 30 patients improved |
Auberger et al. (1985) | 21 | 12 weeks | 600 | Significant effect at weeks 6–8 of treatment |
Pollak et al. (1985) | 10 | 4 weeks | 510 + 120 | Three patients improved |
Perenyi et al. (1985) | 10 | 4 weeks | 300–600 | Reduced AIMS score, no significant effect |
Leblhuber et al. (1987) | 12 | 3 weeks | 300 | Significant effect |
Diedrich and Müller (1989) | 1 | 8 months | 150 | Complete improvement |
Reproduced with permission from Ebel H. Therapy of neuroleptic-induced extrapyramidal movement disorders. Neurol Psych Brain Res 1994; 2:140–151. © Elsevier.
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