| Centers . | Conclusions . |
|---|---|
Korea and Rhodesia | Ambulant outpatient chemotherapy treatment with isoniazid and PAS for 18 months was highly successful |
Daily addition of streptomycin not necessary | |
Korea | No extra benefit from rest in hospital for 6 months |
Masan | No benefit from plaster jacket for first few months |
Pusan | |
Rhodesia | Debridement as a surgical procedure offered no advantage over ambulant chemotherapy |
Rhodesia versus Hong Kong | Radical surgery had no advantage over ambulant chemotherapy in preservation of life and health and in achievement of favorable status |
Radical surgery may achieve favorable status quickly with earlier fusion and decreased tendency for progress in deformity | |
Madras, India | Short-course chemotherapy with daily isoniazid and rifampin for 9 months achieved higher rate (98 per cent) of favorable status than radical surgery (88 per cent) at 5 years |
| Centers . | Conclusions . |
|---|---|
Korea and Rhodesia | Ambulant outpatient chemotherapy treatment with isoniazid and PAS for 18 months was highly successful |
Daily addition of streptomycin not necessary | |
Korea | No extra benefit from rest in hospital for 6 months |
Masan | No benefit from plaster jacket for first few months |
Pusan | |
Rhodesia | Debridement as a surgical procedure offered no advantage over ambulant chemotherapy |
Rhodesia versus Hong Kong | Radical surgery had no advantage over ambulant chemotherapy in preservation of life and health and in achievement of favorable status |
Radical surgery may achieve favorable status quickly with earlier fusion and decreased tendency for progress in deformity | |
Madras, India | Short-course chemotherapy with daily isoniazid and rifampin for 9 months achieved higher rate (98 per cent) of favorable status than radical surgery (88 per cent) at 5 years |
Inclusion criteria: patients with clinical and radiologic evidence of tuberculosis involving any vertebra from the first dorsal to the first sacrum and without neurologic involvement.
Exclusion criteria: presence of severe extraspinal disease (tuberculous or nontuberculous) or a previous history of antituberculous chemotherapy or surgical intervention.
Favorable status: no residual neurologic impairment, sinuses, clinically evident abscess, or impairment of physical activities due to the spinal lesion, and with radiologically quiescent disease. (NB Bony fusion and the severity of deformity were not considered in the assessment for favorable status.)
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