Table 2.6.2
Randomized trials of palliative care
Author, year, intervention typeOutcomes
SymptomsQuality of lifeMoodSatisfactionResource useSurvival

Pantilat et al., 2010

Study performed 2002–2003

Consultant MD modela

No difference

Not measured

Depression not reported, anxiety no difference

Not measured

Not measured

Not measured

Rabow et al., 2004

Consultant MD model

Less dyspnoea, P = 0.01, no change in pain

No difference

Less anxiety (P = 0.05), no change in depression (P = 0.28)

No difference

No difference

Not measured

Brumley et al., 2007

Interdisciplinary palliative care team (IPCT)

Not measured

Not measured

Not measured

Improved, P <0.05

Cost $12,670 vs $20,222, P = 0.03

Hospital days reduced by 4.36 (P <0.001)

No difference

Gade et al., 2008

IPCT

No difference

No difference

No difference

IPCS patients reported greater satisfaction with their care experience (P = 0.04)

and providers’ communication (P = 0.0004)

Total mean health costs $6766 lower (IPCS: $14,486; UC: $21,252, P <0.001). Net cost savings of $4855 (staffing costs) per patient (P <0.001).

No difference

Bakitas et al., 2009

Nursing education intervention

Improved

P = 0.06

Improved

P = 0.02

Improved

P = 0.02

Not measured

No difference

No difference

Temel et al., 2010

IPCT

Improved

P = 0.04

Improved

P = 0.03

Less depression

P = 0.01

Not measured

Less aggressive care

P = 0.05

Costs about $2200 less per patient with PC

11.6 vs 8.9 months

P = 0.02

Meyers et al., 2011

Three education sessions in the first month to learn problem-solving skills

Not measured

Patients: no difference.

Caregivers: declined at less than half the rate of control, P = 0.02

No difference

Not measured

Not measured

Not measured

Zimmerman et al., 2012

Cluster randomized trial of palliative care alongside usual oncology care

Improved

Improved

Improved

Not reported

Not yet reported

Equal

Author, year, intervention typeOutcomes
SymptomsQuality of lifeMoodSatisfactionResource useSurvival

Pantilat et al., 2010

Study performed 2002–2003

Consultant MD modela

No difference

Not measured

Depression not reported, anxiety no difference

Not measured

Not measured

Not measured

Rabow et al., 2004

Consultant MD model

Less dyspnoea, P = 0.01, no change in pain

No difference

Less anxiety (P = 0.05), no change in depression (P = 0.28)

No difference

No difference

Not measured

Brumley et al., 2007

Interdisciplinary palliative care team (IPCT)

Not measured

Not measured

Not measured

Improved, P <0.05

Cost $12,670 vs $20,222, P = 0.03

Hospital days reduced by 4.36 (P <0.001)

No difference

Gade et al., 2008

IPCT

No difference

No difference

No difference

IPCS patients reported greater satisfaction with their care experience (P = 0.04)

and providers’ communication (P = 0.0004)

Total mean health costs $6766 lower (IPCS: $14,486; UC: $21,252, P <0.001). Net cost savings of $4855 (staffing costs) per patient (P <0.001).

No difference

Bakitas et al., 2009

Nursing education intervention

Improved

P = 0.06

Improved

P = 0.02

Improved

P = 0.02

Not measured

No difference

No difference

Temel et al., 2010

IPCT

Improved

P = 0.04

Improved

P = 0.03

Less depression

P = 0.01

Not measured

Less aggressive care

P = 0.05

Costs about $2200 less per patient with PC

11.6 vs 8.9 months

P = 0.02

Meyers et al., 2011

Three education sessions in the first month to learn problem-solving skills

Not measured

Patients: no difference.

Caregivers: declined at less than half the rate of control, P = 0.02

No difference

Not measured

Not measured

Not measured

Zimmerman et al., 2012

Cluster randomized trial of palliative care alongside usual oncology care

Improved

Improved

Improved

Not reported

Not yet reported

Equal

a

The model was a consultant physician who was not a member of the team and made recommendations which were not followed the majority of the time. The primary care provider followed recommendations for opioid prescription in 8% of cases, and antidepressant prescription only 17% of cases. This may partly explain the lack of effect

AD, advance directive; ED, emergency department; IPCS, interdisciplinary palliative care service; IPCT, Interdisciplinary palliative care team; OR, odds ratio; PC, palliative care; UC, usual care.

Source: data from personal communication, Steve Pantilat MD, May 2, 2011.

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