Table 14.1.9
Clinical findings in lumbosacral plexopathy due to cancer
Upper plexopathyLower plexopathyPanplexopathy

Local pain

Lower abdomen

Buttock, perineum

Lumbosacral

Referred pain

Flank, iliac crest

Hip and ankle

Variable

Radicular pain

Anterolateral thigh

Posterolateral thigh, leg

Variable

Paraesthesiae

Anterior thigh

Perineum, thigh, sole

Anterior thigh, leg, foot

Motor and reflex changes

L2–L4

L5–S1

L2–S2

Proximal leg weakness

Distal leg weakness

Weakness can affect different muscle groups and reflexes

Patella reflex

Ankle reflex

Sensory loss

Anterolateral thigh

Posterior thigh, sole

Anterior thigh, leg

Tenderness

Lumbar

Sciatic notch, sacrum

Lumbosacral

Positive SLRT

    Direct

50%

50%

83%

    Reverse

15%

50%

83%

Leg oedema

41%

37%

83%

Rectal mass

25%

43%

15%

Anal sphincter weakness

0

50%

0

Upper plexopathyLower plexopathyPanplexopathy

Local pain

Lower abdomen

Buttock, perineum

Lumbosacral

Referred pain

Flank, iliac crest

Hip and ankle

Variable

Radicular pain

Anterolateral thigh

Posterolateral thigh, leg

Variable

Paraesthesiae

Anterior thigh

Perineum, thigh, sole

Anterior thigh, leg, foot

Motor and reflex changes

L2–L4

L5–S1

L2–S2

Proximal leg weakness

Distal leg weakness

Weakness can affect different muscle groups and reflexes

Patella reflex

Ankle reflex

Sensory loss

Anterolateral thigh

Posterior thigh, sole

Anterior thigh, leg

Tenderness

Lumbar

Sciatic notch, sacrum

Lumbosacral

Positive SLRT

    Direct

50%

50%

83%

    Reverse

15%

50%

83%

Leg oedema

41%

37%

83%

Rectal mass

25%

43%

15%

Anal sphincter weakness

0

50%

0

SLRT, straight leg raising test or Lasegue manoeuvre.

Adapted with permission from
Jaeckle et al., The natural history of lumbosacral plexopathy in cancer, Neurology, Volume 35, Issue 1, pp.8–15, Copyright © 1985 American Academy of Neurology.reference
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