Table 14.1.10
Paraneoplastic neurological syndromes
Location of syndromeReference

Brain and cranial nerves

Limbic encephalitis

Gultekin et al., 2000

Brainstem encephalitis

Barnett et al., 2001

Cerebellar degeneration

Peterson et al., 1992; Cao et al., 1999

Opsoclonus—myoclonus

Bataller et al., 2001

Visual syndromes

     Cancer-associated retinopathy

Goldstein et al., 1999

     Optic neuritis

Lieberman et al., 1999

Chorea

Croteau et al., 2001

Parkinsonism

Golbe et a1., 1989

Spinal cord

     Necrotizing myelopathy

Rudnicki and Dalmau, 2000

     Inflammatory myelitis

Babikian et al., 1985; Hedges et al., 1988

     Motor neuron disease (amyotrophic lateral sclerosis)

Younger, 2000

     Subacute motor neuronopathy

Schold et al., 1979

     Stiff-person syndrome

Brown and Marsden, 1999; Silverman, 1999

Dorsal-root ganglia

Sensory neuronopathy

Graus et al., 2001

Peripheral nerves

Antoine et al., 1999; Rudnicki and Dalmau, 2000

     Autonomic neuropathy

Lee et al., 2001

     Acute sensorimotor neuropathy

     Polyradiculoneuropathy (Guillain–Barré syndrome)

Lisak et al., 1977

     Brachial neuritis

Lachance et al., 1977

     Chronic sensorimotor neuropathy

Antoine et al., 1999

     Vasculitic neuropathy

Blumenthal et al., 1998

     Neuromyotonia

Vincent, 2000; Lahrmann et al., 2001

Neuromuscular junction

     Lambert–Eaton myasthenic syndrome

Carpentier and Delattre

     Myasthenia gravis

Vernino et al., 1999

Muscle

     Polymyositis or dermatomyositis

Stockton et al., 2001

     Necrotizing myopathy

Levin et al., 1998

     Myotonia

Pascual et al., 1994

Location of syndromeReference

Brain and cranial nerves

Limbic encephalitis

Gultekin et al., 2000

Brainstem encephalitis

Barnett et al., 2001

Cerebellar degeneration

Peterson et al., 1992; Cao et al., 1999

Opsoclonus—myoclonus

Bataller et al., 2001

Visual syndromes

     Cancer-associated retinopathy

Goldstein et al., 1999

     Optic neuritis

Lieberman et al., 1999

Chorea

Croteau et al., 2001

Parkinsonism

Golbe et a1., 1989

Spinal cord

     Necrotizing myelopathy

Rudnicki and Dalmau, 2000

     Inflammatory myelitis

Babikian et al., 1985; Hedges et al., 1988

     Motor neuron disease (amyotrophic lateral sclerosis)

Younger, 2000

     Subacute motor neuronopathy

Schold et al., 1979

     Stiff-person syndrome

Brown and Marsden, 1999; Silverman, 1999

Dorsal-root ganglia

Sensory neuronopathy

Graus et al., 2001

Peripheral nerves

Antoine et al., 1999; Rudnicki and Dalmau, 2000

     Autonomic neuropathy

Lee et al., 2001

     Acute sensorimotor neuropathy

     Polyradiculoneuropathy (Guillain–Barré syndrome)

Lisak et al., 1977

     Brachial neuritis

Lachance et al., 1977

     Chronic sensorimotor neuropathy

Antoine et al., 1999

     Vasculitic neuropathy

Blumenthal et al., 1998

     Neuromyotonia

Vincent, 2000; Lahrmann et al., 2001

Neuromuscular junction

     Lambert–Eaton myasthenic syndrome

Carpentier and Delattre

     Myasthenia gravis

Vernino et al., 1999

Muscle

     Polymyositis or dermatomyositis

Stockton et al., 2001

     Necrotizing myopathy

Levin et al., 1998

     Myotonia

Pascual et al., 1994

Reproduced with permission from
Darnell, R. B., and Posner, J. B., Paraneoplastic syndromes involving the Nervous System, New England Journal of Medicine, Volume 349, Issue, pp.1543–54, Copyright © 2003 Massachusetts Medical Society. All rights reserved.reference
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