Haemoptysis

Blood is coughed up, eg frothy, alkaline, and bright red, often in a context of known chest disease (vomited blood is acidic and dark).

Respiratory causes:

1 Infective

tb; bronchiectasis; bronchitis; pneumonia; lung abscess; copd; fungi (eg aspergillosis); viruses (from pneumonitis, cryoglobulinaemia, eg with hepatitis viruses, hiv-associated pneumocystosis, or mai, p411). Helminths: paragonimiasis (p445); hydatid (p444); schistosomiasis.

2 Neoplastic

Primary or secondary.

3 Vascular

Lung infarction (pe); vasculitis (anca-associated; ra; sle); hereditary haemorrhagic telangiectasia; av malformation; capillaritis.

4 Parenchymal

Diffuse interstitial fibrosis; sarcoidosis; haemosiderosis; Goodpasture's syndrome; cystic fibrosis.

5 Pulmonary hypertension

Idiopathic, thromboembolic, congenital cyanotic heart disease (p150), pulmonary fibrosis, bronchiectasis.

6 Coagulopathies

Any—eg thrombocytopenia, p338; dic; warfarin excess.

7 Trauma/foreign body

Eg post-intubation, or an eroding implanted defibrillator.

8 Pseudo-haemoptysis

Munchausen's (p720); aspirated haematemesis; red pigment (prodigiosin) from Serratia marcescens in sputum.

1 Infective

tb; bronchiectasis; bronchitis; pneumonia; lung abscess; copd; fungi (eg aspergillosis); viruses (from pneumonitis, cryoglobulinaemia, eg with hepatitis viruses, hiv-associated pneumocystosis, or mai, p411). Helminths: paragonimiasis (p445); hydatid (p444); schistosomiasis.

2 Neoplastic

Primary or secondary.

3 Vascular

Lung infarction (pe); vasculitis (anca-associated; ra; sle); hereditary haemorrhagic telangiectasia; av malformation; capillaritis.

4 Parenchymal

Diffuse interstitial fibrosis; sarcoidosis; haemosiderosis; Goodpasture's syndrome; cystic fibrosis.

5 Pulmonary hypertension

Idiopathic, thromboembolic, congenital cyanotic heart disease (p150), pulmonary fibrosis, bronchiectasis.

6 Coagulopathies

Any—eg thrombocytopenia, p338; dic; warfarin excess.

7 Trauma/foreign body

Eg post-intubation, or an eroding implanted defibrillator.

8 Pseudo-haemoptysis

Munchausen's (p720); aspirated haematemesis; red pigment (prodigiosin) from Serratia marcescens in sputum.
Rare causes refuse to be classified neatly: vascular causes may have infective origins, eg hydatid cyst may count as a foreign body, and infection, and vascular if it fistulates with the aorta; ditto for infected (mycotic) aneurysm rupture, or tb aortitis. Infective causes entailing coagulopathy: dengue; leptospirosis. In monthly haemoptysis, think of lung endometriosis.
Haemoptysis may need treating in its own right, if massive (eg trauma, tb, hydatid cyst, cancer, av malformation): call chest team, consider intervential radiology input (danger is drowning: lobe resection, endobronchial tamponade, or arterial embolization may be needed). Set up ivi, do cxr, blood gases, fbc, inr/aptt, crossmatch. If distressing, give prompt  iv morphine, eg if inoperable malignancy.
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