Table 2. Open in new tab Mean Fitness,...

	Exercise	Waitlist
VO₂max	33.92 (7.4)	38.2 (7.8)	0.54	31.48 (8.87)	32.97 (10.18)	0.16
BMI	25.5 (2.65)	25.11 (2.82)		25.01 (7.81)	25.73 (7.24)
RiSE task	2.75 (0.45)	3.00 (0.57)	0.49	3.73 (0.44)	3.13 (0.56)	−0.083
WRAT	105.83 (13.38)	114.83 (13.64)		114.8 (14.97)	110.4 (12.26)
Positive symptoms	12.08 (3.52)	8 (3.46)	1.12	13.50 (3.90)	11.38 (3.82)	0.55
Negative symptoms	5.54 (3.87)	4.38 (3.84)	0.31	7.33 (5.45)	6.67 (4.68)	0.13
Hippocampal subfields (mm³)
Total subiculum	889.184 (111.674)	889.868 (111.375)	0.006	772.823 (108.34)	762.393 (126.12)	−0.089
Head	393.723 (54.263)	394.896 (55.394)	0.021	346.718 (58.485)	342.567 (62.993)	−0.068
Left	196.268 (25.966)	197.508 (26.01)	0.048	177.011 (31.148)	173.907 (33.563)	−0.096
Right	197.456 (30.647)	197.388 (31.974)	0.048	169.707 (29.142)	168.659 (31.903)	−0.034
Body	495.461 (70.247)	494.972 (70.351)	0.007	426.105 (68.505)	419.826 (70.448)	−0.09
Left	251.337 (41.901)	253.196 (40.779)	0.045	221.768 (44.178)	223.293 (38.355)	−0.037
Right	241.776 (33.678)	244.123 (33.742)	0.07	204.336 (30.57)	196.534 (35.879)	−0.234
Hippocampal-occipital connectivity (b-values)	0.15 (0.11)	0.07 (0.12)	0.67	0.06 (0.15)	0.11 (0.18)	−0.29

Exercise

Waitlist

Pretrial

Posttrial

Change (d)

Pretrial

Posttrial

Change (d)

VO₂max

33.92 (7.4)

38.2 (7.8)

0.54

31.48 (8.87)

32.97 (10.18)

0.16

BMI

25.5 (2.65)

25.11 (2.82)

25.01 (7.81)

25.73 (7.24)

RiSE task

2.75 (0.45)

3.00 (0.57)

0.49

3.73 (0.44)

3.13 (0.56)

−0.083

WRAT

105.83 (13.38)

114.83 (13.64)

114.8 (14.97)

110.4 (12.26)

Positive symptoms

12.08 (3.52)

8 (3.46)

1.12

13.50 (3.90)

11.38 (3.82)

0.55

Negative symptoms

5.54 (3.87)

4.38 (3.84)

0.31

7.33 (5.45)

6.67 (4.68)

0.13

Hippocampal subfields (mm³)

Total subiculum

889.184 (111.674)

889.868 (111.375)

0.006

772.823 (108.34)

762.393 (126.12)

−0.089

Head

393.723 (54.263)

394.896 (55.394)

0.021

346.718 (58.485)

342.567 (62.993)

−0.068

Left

196.268 (25.966)

197.508 (26.01)

0.048

177.011 (31.148)

173.907 (33.563)

−0.096

Right

197.456 (30.647)

197.388 (31.974)

0.048

169.707 (29.142)

168.659 (31.903)

−0.034

Body

495.461 (70.247)

494.972 (70.351)

0.007

426.105 (68.505)

419.826 (70.448)

−0.09

Left

251.337 (41.901)

253.196 (40.779)

0.045

221.768 (44.178)

223.293 (38.355)

−0.037

Right

241.776 (33.678)

244.123 (33.742)

0.07

204.336 (30.57)

196.534 (35.879)

−0.234

Hippocampal-occipital connectivity (b-values)

0.15 (0.11)

0.07 (0.12)

0.67

0.06 (0.15)

0.11 (0.18)

−0.29

	Exercise	Waitlist
VO₂max	33.92 (7.4)	38.2 (7.8)	0.54	31.48 (8.87)	32.97 (10.18)	0.16
BMI	25.5 (2.65)	25.11 (2.82)		25.01 (7.81)	25.73 (7.24)
RiSE task	2.75 (0.45)	3.00 (0.57)	0.49	3.73 (0.44)	3.13 (0.56)	−0.083
WRAT	105.83 (13.38)	114.83 (13.64)		114.8 (14.97)	110.4 (12.26)
Positive symptoms	12.08 (3.52)	8 (3.46)	1.12	13.50 (3.90)	11.38 (3.82)	0.55
Negative symptoms	5.54 (3.87)	4.38 (3.84)	0.31	7.33 (5.45)	6.67 (4.68)	0.13
Hippocampal subfields (mm³)
Total subiculum	889.184 (111.674)	889.868 (111.375)	0.006	772.823 (108.34)	762.393 (126.12)	−0.089
Head	393.723 (54.263)	394.896 (55.394)	0.021	346.718 (58.485)	342.567 (62.993)	−0.068
Left	196.268 (25.966)	197.508 (26.01)	0.048	177.011 (31.148)	173.907 (33.563)	−0.096
Right	197.456 (30.647)	197.388 (31.974)	0.048	169.707 (29.142)	168.659 (31.903)	−0.034
Body	495.461 (70.247)	494.972 (70.351)	0.007	426.105 (68.505)	419.826 (70.448)	−0.09
Left	251.337 (41.901)	253.196 (40.779)	0.045	221.768 (44.178)	223.293 (38.355)	−0.037
Right	241.776 (33.678)	244.123 (33.742)	0.07	204.336 (30.57)	196.534 (35.879)	−0.234
Hippocampal-occipital connectivity (b-values)	0.15 (0.11)	0.07 (0.12)	0.67	0.06 (0.15)	0.11 (0.18)	−0.29

Table 2.

Open in new tab

Mean Fitness, Cognitive, Clinical Symptoms, Hippocampal Subfield Volumes, and Connectivity by Randomized Control Condition and Timepoint

	Exercise			Waitlist
	Pretrial	Posttrial	Change (d)	Pretrial	Posttrial	Change (d)
VO₂max	33.92 (7.4)	38.2 (7.8)	0.54	31.48 (8.87)	32.97 (10.18)	0.16
BMI	25.5 (2.65)	25.11 (2.82)		25.01 (7.81)	25.73 (7.24)
RiSE task	2.75 (0.45)	3.00 (0.57)	0.49	3.73 (0.44)	3.13 (0.56)	−0.083
WRAT	105.83 (13.38)	114.83 (13.64)		114.8 (14.97)	110.4 (12.26)
Positive symptoms	12.08 (3.52)	8 (3.46)	1.12	13.50 (3.90)	11.38 (3.82)	0.55
Negative symptoms	5.54 (3.87)	4.38 (3.84)	0.31	7.33 (5.45)	6.67 (4.68)	0.13
Hippocampal subfields (mm³)
Total subiculum	889.184 (111.674)	889.868 (111.375)	0.006	772.823 (108.34)	762.393 (126.12)	−0.089
Head	393.723 (54.263)	394.896 (55.394)	0.021	346.718 (58.485)	342.567 (62.993)	−0.068
Left	196.268 (25.966)	197.508 (26.01)	0.048	177.011 (31.148)	173.907 (33.563)	−0.096
Right	197.456 (30.647)	197.388 (31.974)	0.048	169.707 (29.142)	168.659 (31.903)	−0.034
Body	495.461 (70.247)	494.972 (70.351)	0.007	426.105 (68.505)	419.826 (70.448)	−0.09
Left	251.337 (41.901)	253.196 (40.779)	0.045	221.768 (44.178)	223.293 (38.355)	−0.037
Right	241.776 (33.678)	244.123 (33.742)	0.07	204.336 (30.57)	196.534 (35.879)	−0.234
Hippocampal-occipital connectivity (b-values)	0.15 (0.11)	0.07 (0.12)	0.67	0.06 (0.15)	0.11 (0.18)	−0.29

	Exercise			Waitlist
	Pretrial	Posttrial	Change (d)	Pretrial	Posttrial	Change (d)
VO₂max	33.92 (7.4)	38.2 (7.8)	0.54	31.48 (8.87)	32.97 (10.18)	0.16
BMI	25.5 (2.65)	25.11 (2.82)		25.01 (7.81)	25.73 (7.24)
RiSE task	2.75 (0.45)	3.00 (0.57)	0.49	3.73 (0.44)	3.13 (0.56)	−0.083
WRAT	105.83 (13.38)	114.83 (13.64)		114.8 (14.97)	110.4 (12.26)
Positive symptoms	12.08 (3.52)	8 (3.46)	1.12	13.50 (3.90)	11.38 (3.82)	0.55
Negative symptoms	5.54 (3.87)	4.38 (3.84)	0.31	7.33 (5.45)	6.67 (4.68)	0.13
Hippocampal subfields (mm³)
Total subiculum	889.184 (111.674)	889.868 (111.375)	0.006	772.823 (108.34)	762.393 (126.12)	−0.089
Head	393.723 (54.263)	394.896 (55.394)	0.021	346.718 (58.485)	342.567 (62.993)	−0.068
Left	196.268 (25.966)	197.508 (26.01)	0.048	177.011 (31.148)	173.907 (33.563)	−0.096
Right	197.456 (30.647)	197.388 (31.974)	0.048	169.707 (29.142)	168.659 (31.903)	−0.034
Body	495.461 (70.247)	494.972 (70.351)	0.007	426.105 (68.505)	419.826 (70.448)	−0.09
Left	251.337 (41.901)	253.196 (40.779)	0.045	221.768 (44.178)	223.293 (38.355)	−0.037
Right	241.776 (33.678)	244.123 (33.742)	0.07	204.336 (30.57)	196.534 (35.879)	−0.234
Hippocampal-occipital connectivity (b-values)	0.15 (0.11)	0.07 (0.12)	0.67	0.06 (0.15)	0.11 (0.18)	−0.29

This Feature Is Available To Subscribers Only