Excess hazard ratio (EHR) of death in patients with malignant melanoma of the skin, by morphological type (reference category superficial spreading melanoma) in Germany, Spain and Norway
| . | Germany (Lower Saxony) . | Spanish registriesa . | Norwayb . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| . | n (%) . | Model 1, EHR (95% CI) . | Model 2, EHR (95% CI) . | n (%) . | Model 1, EHR (95% CI) . | Model 2, HR (95% CI) . | n (%) . | Model 1, EHR (95% CI) . | Model 2, EHR (95% CI) . |
| Superficial spreading | 9326 (58.9) | 1.0 | 1.0 | 1642 (39.8) | 1.0 | 1.0 | 8624 (54.0) | 1.0 | 1.0 |
| Lentigo maligna | 1305 (8.2) | 0.2 (0.0–35.1) | 0.1 (0.0–26.9) | 232 (5.6) | 0.4 (0.0–17.2) | 0.4 (0.1–2.1) | 478 (3.0) | 0.3 (0.1–6.4) | 0.5 (0.2–1.4) |
| Nodular | 1514 (9.6) | 21.8 (14.7–32.3) | 13.5 (9.6–18.9) | 627 (15.2) | 12.1 (8.1–18.1) | 6.7 (4.8–9.3) | 3234 (20.3) | 6.7 (5.7–7.9) | 4.1 (3.6–4.8) |
| Acral lentiginous | 341 (2.2) | 15.2 (9.0–25.5) | 10.8 (6.8–17.1) | 138 (3.4) | 9.0 (5.2–15.5) | 5.0 (3.1–8.1) | 91 (0.6) | 1.7 (0.5–5.1) | 2.2 (1.0–4.9) |
| Malignant melanoma, NOS | 2953 (18.7) | 6.5 (4.3–9.9) | 5.4 (3.8–7.6) | 1178 (28.6) | 4.2 (2.8–6.4) | 2.9 (2.0–4.0) | 3338 (20.9) | 3.9 (3.3–4.7) | 2.8 (2.4–3.3) |
| Other morphologies | 385 (2.4) | 8.6 (4.7–15.6) | 6.5 (3.8–11.0) | 307 (7.4) | 5.6 (3.4–9.2) | 3.7 (2.4–5.6) | 201 (1.2) | 4.5 (2.9–6.9) | 2.4 (1.6–3.7) |
| . | Germany (Lower Saxony) . | Spanish registriesa . | Norwayb . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| . | n (%) . | Model 1, EHR (95% CI) . | Model 2, EHR (95% CI) . | n (%) . | Model 1, EHR (95% CI) . | Model 2, HR (95% CI) . | n (%) . | Model 1, EHR (95% CI) . | Model 2, EHR (95% CI) . |
| Superficial spreading | 9326 (58.9) | 1.0 | 1.0 | 1642 (39.8) | 1.0 | 1.0 | 8624 (54.0) | 1.0 | 1.0 |
| Lentigo maligna | 1305 (8.2) | 0.2 (0.0–35.1) | 0.1 (0.0–26.9) | 232 (5.6) | 0.4 (0.0–17.2) | 0.4 (0.1–2.1) | 478 (3.0) | 0.3 (0.1–6.4) | 0.5 (0.2–1.4) |
| Nodular | 1514 (9.6) | 21.8 (14.7–32.3) | 13.5 (9.6–18.9) | 627 (15.2) | 12.1 (8.1–18.1) | 6.7 (4.8–9.3) | 3234 (20.3) | 6.7 (5.7–7.9) | 4.1 (3.6–4.8) |
| Acral lentiginous | 341 (2.2) | 15.2 (9.0–25.5) | 10.8 (6.8–17.1) | 138 (3.4) | 9.0 (5.2–15.5) | 5.0 (3.1–8.1) | 91 (0.6) | 1.7 (0.5–5.1) | 2.2 (1.0–4.9) |
| Malignant melanoma, NOS | 2953 (18.7) | 6.5 (4.3–9.9) | 5.4 (3.8–7.6) | 1178 (28.6) | 4.2 (2.8–6.4) | 2.9 (2.0–4.0) | 3338 (20.9) | 3.9 (3.3–4.7) | 2.8 (2.4–3.3) |
| Other morphologies | 385 (2.4) | 8.6 (4.7–15.6) | 6.5 (3.8–11.0) | 307 (7.4) | 5.6 (3.4–9.2) | 3.7 (2.4–5.6) | 201 (1.2) | 4.5 (2.9–6.9) | 2.4 (1.6–3.7) |
NOS, not otherwise specified. EHR, excess hazard ratio. aGranada and Basque Country. bNational coverage. Model 1 included only morphology. Model 2 included morphology, sex, age and stage at diagnosis.
Excess hazard ratio (EHR) of death in patients with malignant melanoma of the skin, by morphological type (reference category superficial spreading melanoma) in Germany, Spain and Norway
| . | Germany (Lower Saxony) . | Spanish registriesa . | Norwayb . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| . | n (%) . | Model 1, EHR (95% CI) . | Model 2, EHR (95% CI) . | n (%) . | Model 1, EHR (95% CI) . | Model 2, HR (95% CI) . | n (%) . | Model 1, EHR (95% CI) . | Model 2, EHR (95% CI) . |
| Superficial spreading | 9326 (58.9) | 1.0 | 1.0 | 1642 (39.8) | 1.0 | 1.0 | 8624 (54.0) | 1.0 | 1.0 |
| Lentigo maligna | 1305 (8.2) | 0.2 (0.0–35.1) | 0.1 (0.0–26.9) | 232 (5.6) | 0.4 (0.0–17.2) | 0.4 (0.1–2.1) | 478 (3.0) | 0.3 (0.1–6.4) | 0.5 (0.2–1.4) |
| Nodular | 1514 (9.6) | 21.8 (14.7–32.3) | 13.5 (9.6–18.9) | 627 (15.2) | 12.1 (8.1–18.1) | 6.7 (4.8–9.3) | 3234 (20.3) | 6.7 (5.7–7.9) | 4.1 (3.6–4.8) |
| Acral lentiginous | 341 (2.2) | 15.2 (9.0–25.5) | 10.8 (6.8–17.1) | 138 (3.4) | 9.0 (5.2–15.5) | 5.0 (3.1–8.1) | 91 (0.6) | 1.7 (0.5–5.1) | 2.2 (1.0–4.9) |
| Malignant melanoma, NOS | 2953 (18.7) | 6.5 (4.3–9.9) | 5.4 (3.8–7.6) | 1178 (28.6) | 4.2 (2.8–6.4) | 2.9 (2.0–4.0) | 3338 (20.9) | 3.9 (3.3–4.7) | 2.8 (2.4–3.3) |
| Other morphologies | 385 (2.4) | 8.6 (4.7–15.6) | 6.5 (3.8–11.0) | 307 (7.4) | 5.6 (3.4–9.2) | 3.7 (2.4–5.6) | 201 (1.2) | 4.5 (2.9–6.9) | 2.4 (1.6–3.7) |
| . | Germany (Lower Saxony) . | Spanish registriesa . | Norwayb . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| . | n (%) . | Model 1, EHR (95% CI) . | Model 2, EHR (95% CI) . | n (%) . | Model 1, EHR (95% CI) . | Model 2, HR (95% CI) . | n (%) . | Model 1, EHR (95% CI) . | Model 2, EHR (95% CI) . |
| Superficial spreading | 9326 (58.9) | 1.0 | 1.0 | 1642 (39.8) | 1.0 | 1.0 | 8624 (54.0) | 1.0 | 1.0 |
| Lentigo maligna | 1305 (8.2) | 0.2 (0.0–35.1) | 0.1 (0.0–26.9) | 232 (5.6) | 0.4 (0.0–17.2) | 0.4 (0.1–2.1) | 478 (3.0) | 0.3 (0.1–6.4) | 0.5 (0.2–1.4) |
| Nodular | 1514 (9.6) | 21.8 (14.7–32.3) | 13.5 (9.6–18.9) | 627 (15.2) | 12.1 (8.1–18.1) | 6.7 (4.8–9.3) | 3234 (20.3) | 6.7 (5.7–7.9) | 4.1 (3.6–4.8) |
| Acral lentiginous | 341 (2.2) | 15.2 (9.0–25.5) | 10.8 (6.8–17.1) | 138 (3.4) | 9.0 (5.2–15.5) | 5.0 (3.1–8.1) | 91 (0.6) | 1.7 (0.5–5.1) | 2.2 (1.0–4.9) |
| Malignant melanoma, NOS | 2953 (18.7) | 6.5 (4.3–9.9) | 5.4 (3.8–7.6) | 1178 (28.6) | 4.2 (2.8–6.4) | 2.9 (2.0–4.0) | 3338 (20.9) | 3.9 (3.3–4.7) | 2.8 (2.4–3.3) |
| Other morphologies | 385 (2.4) | 8.6 (4.7–15.6) | 6.5 (3.8–11.0) | 307 (7.4) | 5.6 (3.4–9.2) | 3.7 (2.4–5.6) | 201 (1.2) | 4.5 (2.9–6.9) | 2.4 (1.6–3.7) |
NOS, not otherwise specified. EHR, excess hazard ratio. aGranada and Basque Country. bNational coverage. Model 1 included only morphology. Model 2 included morphology, sex, age and stage at diagnosis.
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