| Comparison Group . | ADL Disability . | Instrumental ADL Disability . | Mobility Disability . | |||
|---|---|---|---|---|---|---|
| First author, Publication Year . | Statistical Measure (95% CI) . | First Author, Publication Year . | Statistical measure (95% CI) . | First Author, Publication Year . | Statistical Measure (95% CI) . | |
| Frailty without cognitive impairment (physical frailty) versus robust | Avila-Funes (2009) | OR 2.50 (1.14–5.49) | Avila-Funes (2009) | OR 2.30 (1.49–3.55) | Avila-Funes (2009) | OR 1.32 (0.70–2.52) |
| Chen (2020) | OR 2.31 (1.53–3.48) | Chen (2020) | OR 2.23 (1.43–3.47) | Chen (2020) | OR 1.29 (0.52–3.18) | |
| Ma (2021) | OR 5.47 (2.03–14.75) | |||||
| Aliberti (2019) | sHR 1.70 (1.40–2.00) | |||||
| Frailty with cognitive impairment (cognitive frailty) versus robust | Avila-Funes (2009) | OR 5.60 (2.13–14.70) | Avila-Funes (2009) | OR 3.17 (1.47–6.83) | Avila-Funes (2009) | OR 3.88 (0.78–19.41) |
| Chen (2020) | OR 2.22 (0.97–5.08) | Chen (2020) | OR 2.80 (1.00–7.87) | Chen (2020) | OR 1.00 | |
| Ma (2021) | OR 10.48 (2.98–36.80) | Shimada (2016) | OR 2.63 (1.74–3.97) | Liu (2018) | aRR 3.10 (2.60–3.60) | |
| Aliberti (2019) | sHR 2.00 (1.60–2.60) | Liu (2018) | aRR 2.30 (2.10–2.60) | |||
| Liu (2018) | aRR 20.60 (15.70–26.90) | |||||
| Prefrailty without cognitive impairment versus robust | Avila-Funes (2009) | OR 0.72 (0.38–1.36) | Avila-Funes (2009) | OR 1.49 (1.17–1.89) | Avila-Funes (2009) | OR 1.34 (1.13–1.59) |
| Ma (2021) | OR 2.34 (1.18–4.63) | |||||
| Prefrailty with cognitive impairment versus robust | Avila-Funes (2009) | OR 1.17 (0.45–3.04) | Avila-Funes (2009) | OR 2.83 (1.91–4.19) | Avila-Funes (2009) | OR 1.15 (0.76–1.73) |
| Ma (2021) | OR 3.28 (1.31–8.23) | |||||
| Comparison Group . | ADL Disability . | Instrumental ADL Disability . | Mobility Disability . | |||
|---|---|---|---|---|---|---|
| First author, Publication Year . | Statistical Measure (95% CI) . | First Author, Publication Year . | Statistical measure (95% CI) . | First Author, Publication Year . | Statistical Measure (95% CI) . | |
| Frailty without cognitive impairment (physical frailty) versus robust | Avila-Funes (2009) | OR 2.50 (1.14–5.49) | Avila-Funes (2009) | OR 2.30 (1.49–3.55) | Avila-Funes (2009) | OR 1.32 (0.70–2.52) |
| Chen (2020) | OR 2.31 (1.53–3.48) | Chen (2020) | OR 2.23 (1.43–3.47) | Chen (2020) | OR 1.29 (0.52–3.18) | |
| Ma (2021) | OR 5.47 (2.03–14.75) | |||||
| Aliberti (2019) | sHR 1.70 (1.40–2.00) | |||||
| Frailty with cognitive impairment (cognitive frailty) versus robust | Avila-Funes (2009) | OR 5.60 (2.13–14.70) | Avila-Funes (2009) | OR 3.17 (1.47–6.83) | Avila-Funes (2009) | OR 3.88 (0.78–19.41) |
| Chen (2020) | OR 2.22 (0.97–5.08) | Chen (2020) | OR 2.80 (1.00–7.87) | Chen (2020) | OR 1.00 | |
| Ma (2021) | OR 10.48 (2.98–36.80) | Shimada (2016) | OR 2.63 (1.74–3.97) | Liu (2018) | aRR 3.10 (2.60–3.60) | |
| Aliberti (2019) | sHR 2.00 (1.60–2.60) | Liu (2018) | aRR 2.30 (2.10–2.60) | |||
| Liu (2018) | aRR 20.60 (15.70–26.90) | |||||
| Prefrailty without cognitive impairment versus robust | Avila-Funes (2009) | OR 0.72 (0.38–1.36) | Avila-Funes (2009) | OR 1.49 (1.17–1.89) | Avila-Funes (2009) | OR 1.34 (1.13–1.59) |
| Ma (2021) | OR 2.34 (1.18–4.63) | |||||
| Prefrailty with cognitive impairment versus robust | Avila-Funes (2009) | OR 1.17 (0.45–3.04) | Avila-Funes (2009) | OR 2.83 (1.91–4.19) | Avila-Funes (2009) | OR 1.15 (0.76–1.73) |
| Ma (2021) | OR 3.28 (1.31–8.23) | |||||
Notes: ADL = activities of daily living; aRR = adjusted rate ratio; OR = odds ratio; sHR = sub-hazard ratio.
| Comparison Group . | ADL Disability . | Instrumental ADL Disability . | Mobility Disability . | |||
|---|---|---|---|---|---|---|
| First author, Publication Year . | Statistical Measure (95% CI) . | First Author, Publication Year . | Statistical measure (95% CI) . | First Author, Publication Year . | Statistical Measure (95% CI) . | |
| Frailty without cognitive impairment (physical frailty) versus robust | Avila-Funes (2009) | OR 2.50 (1.14–5.49) | Avila-Funes (2009) | OR 2.30 (1.49–3.55) | Avila-Funes (2009) | OR 1.32 (0.70–2.52) |
| Chen (2020) | OR 2.31 (1.53–3.48) | Chen (2020) | OR 2.23 (1.43–3.47) | Chen (2020) | OR 1.29 (0.52–3.18) | |
| Ma (2021) | OR 5.47 (2.03–14.75) | |||||
| Aliberti (2019) | sHR 1.70 (1.40–2.00) | |||||
| Frailty with cognitive impairment (cognitive frailty) versus robust | Avila-Funes (2009) | OR 5.60 (2.13–14.70) | Avila-Funes (2009) | OR 3.17 (1.47–6.83) | Avila-Funes (2009) | OR 3.88 (0.78–19.41) |
| Chen (2020) | OR 2.22 (0.97–5.08) | Chen (2020) | OR 2.80 (1.00–7.87) | Chen (2020) | OR 1.00 | |
| Ma (2021) | OR 10.48 (2.98–36.80) | Shimada (2016) | OR 2.63 (1.74–3.97) | Liu (2018) | aRR 3.10 (2.60–3.60) | |
| Aliberti (2019) | sHR 2.00 (1.60–2.60) | Liu (2018) | aRR 2.30 (2.10–2.60) | |||
| Liu (2018) | aRR 20.60 (15.70–26.90) | |||||
| Prefrailty without cognitive impairment versus robust | Avila-Funes (2009) | OR 0.72 (0.38–1.36) | Avila-Funes (2009) | OR 1.49 (1.17–1.89) | Avila-Funes (2009) | OR 1.34 (1.13–1.59) |
| Ma (2021) | OR 2.34 (1.18–4.63) | |||||
| Prefrailty with cognitive impairment versus robust | Avila-Funes (2009) | OR 1.17 (0.45–3.04) | Avila-Funes (2009) | OR 2.83 (1.91–4.19) | Avila-Funes (2009) | OR 1.15 (0.76–1.73) |
| Ma (2021) | OR 3.28 (1.31–8.23) | |||||
| Comparison Group . | ADL Disability . | Instrumental ADL Disability . | Mobility Disability . | |||
|---|---|---|---|---|---|---|
| First author, Publication Year . | Statistical Measure (95% CI) . | First Author, Publication Year . | Statistical measure (95% CI) . | First Author, Publication Year . | Statistical Measure (95% CI) . | |
| Frailty without cognitive impairment (physical frailty) versus robust | Avila-Funes (2009) | OR 2.50 (1.14–5.49) | Avila-Funes (2009) | OR 2.30 (1.49–3.55) | Avila-Funes (2009) | OR 1.32 (0.70–2.52) |
| Chen (2020) | OR 2.31 (1.53–3.48) | Chen (2020) | OR 2.23 (1.43–3.47) | Chen (2020) | OR 1.29 (0.52–3.18) | |
| Ma (2021) | OR 5.47 (2.03–14.75) | |||||
| Aliberti (2019) | sHR 1.70 (1.40–2.00) | |||||
| Frailty with cognitive impairment (cognitive frailty) versus robust | Avila-Funes (2009) | OR 5.60 (2.13–14.70) | Avila-Funes (2009) | OR 3.17 (1.47–6.83) | Avila-Funes (2009) | OR 3.88 (0.78–19.41) |
| Chen (2020) | OR 2.22 (0.97–5.08) | Chen (2020) | OR 2.80 (1.00–7.87) | Chen (2020) | OR 1.00 | |
| Ma (2021) | OR 10.48 (2.98–36.80) | Shimada (2016) | OR 2.63 (1.74–3.97) | Liu (2018) | aRR 3.10 (2.60–3.60) | |
| Aliberti (2019) | sHR 2.00 (1.60–2.60) | Liu (2018) | aRR 2.30 (2.10–2.60) | |||
| Liu (2018) | aRR 20.60 (15.70–26.90) | |||||
| Prefrailty without cognitive impairment versus robust | Avila-Funes (2009) | OR 0.72 (0.38–1.36) | Avila-Funes (2009) | OR 1.49 (1.17–1.89) | Avila-Funes (2009) | OR 1.34 (1.13–1.59) |
| Ma (2021) | OR 2.34 (1.18–4.63) | |||||
| Prefrailty with cognitive impairment versus robust | Avila-Funes (2009) | OR 1.17 (0.45–3.04) | Avila-Funes (2009) | OR 2.83 (1.91–4.19) | Avila-Funes (2009) | OR 1.15 (0.76–1.73) |
| Ma (2021) | OR 3.28 (1.31–8.23) | |||||
Notes: ADL = activities of daily living; aRR = adjusted rate ratio; OR = odds ratio; sHR = sub-hazard ratio.
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