Table 2.

Summary of risk of bias and applicability based on QUADAS-2

Author (year)Risk of biasApplicability concerns
Patient selectionIndex testReference standardFlow and timingPatient selectionIndex testReference standard
 Dekker (2005)23HighHighLowHighHighHighLow
Fitzpatric (2022)24UnclearLowLowLowLowLowLow
 Lee (2015)25HighUnclearUnclearHighHighHighLow
 Lin (2017)6LowHighLowLowLowHighLow
 Liu (2021)26UnclearHighLowLowUnclearHighLow
 Nayak (2013)27UnclearLowUnclearLowUnclearLowLow
 Subira (2012)28LowLowUnclearLowLowLowLow
 Subira (2015)5UnclearLowUnclearLowUnclearLowLow
 Torre (2020)29LowLowLowLowLowLowLow
van Bussel (2020)30LowUnclearUnclearLowLowUnclearLow
Author (year)Risk of biasApplicability concerns
Patient selectionIndex testReference standardFlow and timingPatient selectionIndex testReference standard
 Dekker (2005)23HighHighLowHighHighHighLow
Fitzpatric (2022)24UnclearLowLowLowLowLowLow
 Lee (2015)25HighUnclearUnclearHighHighHighLow
 Lin (2017)6LowHighLowLowLowHighLow
 Liu (2021)26UnclearHighLowLowUnclearHighLow
 Nayak (2013)27UnclearLowUnclearLowUnclearLowLow
 Subira (2012)28LowLowUnclearLowLowLowLow
 Subira (2015)5UnclearLowUnclearLowUnclearLowLow
 Torre (2020)29LowLowLowLowLowLowLow
van Bussel (2020)30LowUnclearUnclearLowLowUnclearLow
Table 2.

Summary of risk of bias and applicability based on QUADAS-2

Author (year)Risk of biasApplicability concerns
Patient selectionIndex testReference standardFlow and timingPatient selectionIndex testReference standard
 Dekker (2005)23HighHighLowHighHighHighLow
Fitzpatric (2022)24UnclearLowLowLowLowLowLow
 Lee (2015)25HighUnclearUnclearHighHighHighLow
 Lin (2017)6LowHighLowLowLowHighLow
 Liu (2021)26UnclearHighLowLowUnclearHighLow
 Nayak (2013)27UnclearLowUnclearLowUnclearLowLow
 Subira (2012)28LowLowUnclearLowLowLowLow
 Subira (2015)5UnclearLowUnclearLowUnclearLowLow
 Torre (2020)29LowLowLowLowLowLowLow
van Bussel (2020)30LowUnclearUnclearLowLowUnclearLow
Author (year)Risk of biasApplicability concerns
Patient selectionIndex testReference standardFlow and timingPatient selectionIndex testReference standard
 Dekker (2005)23HighHighLowHighHighHighLow
Fitzpatric (2022)24UnclearLowLowLowLowLowLow
 Lee (2015)25HighUnclearUnclearHighHighHighLow
 Lin (2017)6LowHighLowLowLowHighLow
 Liu (2021)26UnclearHighLowLowUnclearHighLow
 Nayak (2013)27UnclearLowUnclearLowUnclearLowLow
 Subira (2012)28LowLowUnclearLowLowLowLow
 Subira (2015)5UnclearLowUnclearLowUnclearLowLow
 Torre (2020)29LowLowLowLowLowLowLow
van Bussel (2020)30LowUnclearUnclearLowLowUnclearLow
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