Table 1 Open in new tab Demography and...

	CDRIE+LHIE− (1) (n = 280)	LHIE+CDRIE− (2) (n = 157)	CDRIE+LHIE+ (3) (n = 46)	P-value (1) vs. (2)	P-value (2) vs. (3)
Demographic
Age (years)
N	280	157	46
Mean ± SD	66.69 ± 14.31	71.08 ± 13.59	70.22 ± 10.11	0.0002	0.1
Females	75/280 (26.8%)	39/157 (24.8%)	19/46 (41.3%)	0.6	0.02
Body mass index (kg/m²)
N	257	142	40
Mean ± SD	27.48 ± 6.21	27.53 ± 5.58	28.32 ± 5.68	0.6	0.4
History of previous endocarditis
Previous endocarditis	16/280 (5.7%)	23/157 (14.6%)	4/46 (8.7%)	0.001	0.2
Type of microorganism
Staphylococcus aureus	6/12 (50.0%)	6/15 (40.0%)	2/3 (66.7%)	0.6	0.5
Methi-S Staphylococcus aureus	6/12 (50.0%)	5/15 (33.3%)	1/3 (33.3%)	0.4	>0.9
Chronic renal failure	71/280 (25.4%)	52/157 (33.1%)	14/46 (30.4%)	0.08	0.7
Diabetes mellitus	110/280 (39.3%)	51/157 (32.5%)	21/46 (45.7%)	0.1	0.1
Heart failure	114/245 (46.5%)	80/141 (56.7%)	14/43 (32.6%)	0.05	0.005
Charlson index
N	232	136	40
Mean ± SD	4.42 ± 3.16	5.41 ± 2.83	4.93 ± 2.04	<0.0001	0.3
Antithrombotic treatment on admission	206/274 (75.2%)	135/155 (87.1%)	40/45 (88.9%)	0.003	0.7
Device therapy
Pacemaker	150/280 (53.6%)	118/157 (75.2%)	28/46 (60.9%)	<0.0001	0.1
ICD (defibrillator)	84/280 (30.0%)	23/157 (14.6%)	8/46 (17.4%)
CRT-D (with ICD)	42/280 (15.0%)	11/157 (7.0%)	6/46 (13.0%)
CRT-P (pacing only)	4/280 (1.4%)	5/157 (3.2%)	4/46 (8.7%)

CDRIE+LHIE− (1)
(n = 280)

LHIE+CDRIE− (2)
(n = 157)

CDRIE+LHIE+ (3)
(n = 46)

P-value
(1) vs. (2)

P-value
(2) vs. (3)

Demographic

Age (years)

280

157

Mean ± SD

66.69 ± 14.31

71.08 ± 13.59

70.22 ± 10.11

0.0002

0.1

Females

75/280 (26.8%)

39/157 (24.8%)

19/46 (41.3%)

0.6

0.02

Body mass index (kg/m²)

257

142

Mean ± SD

27.48 ± 6.21

27.53 ± 5.58

28.32 ± 5.68

0.6

0.4

History of previous endocarditis

Previous endocarditis

16/280 (5.7%)

23/157 (14.6%)

4/46 (8.7%)

0.001

0.2

Type of microorganism

Staphylococcus aureus

6/12 (50.0%)

6/15 (40.0%)

2/3 (66.7%)

0.6

0.5

Methi-S Staphylococcus aureus

6/12 (50.0%)

5/15 (33.3%)

1/3 (33.3%)

0.4

>0.9

Chronic renal failure

71/280 (25.4%)

52/157 (33.1%)

14/46 (30.4%)

0.08

0.7

Diabetes mellitus

110/280 (39.3%)

51/157 (32.5%)

21/46 (45.7%)

0.1

Heart failure

114/245 (46.5%)

80/141 (56.7%)

14/43 (32.6%)

0.05

0.005

Charlson index

232

136

Mean ± SD

4.42 ± 3.16

5.41 ± 2.83

4.93 ± 2.04

<0.0001

0.3

Antithrombotic treatment on admission

206/274 (75.2%)

135/155 (87.1%)

40/45 (88.9%)

0.003

0.7

Device therapy

Pacemaker

150/280 (53.6%)

118/157 (75.2%)

28/46 (60.9%)

<0.0001

0.1

ICD (defibrillator)

84/280 (30.0%)

23/157 (14.6%)

8/46 (17.4%)

CRT-D (with ICD)

42/280 (15.0%)

11/157 (7.0%)

6/46 (13.0%)

CRT-P (pacing only)

4/280 (1.4%)

5/157 (3.2%)

4/46 (8.7%)

	CDRIE+LHIE− (1) (n = 280)	LHIE+CDRIE− (2) (n = 157)	CDRIE+LHIE+ (3) (n = 46)	P-value (1) vs. (2)	P-value (2) vs. (3)
Demographic
Age (years)
N	280	157	46
Mean ± SD	66.69 ± 14.31	71.08 ± 13.59	70.22 ± 10.11	0.0002	0.1
Females	75/280 (26.8%)	39/157 (24.8%)	19/46 (41.3%)	0.6	0.02
Body mass index (kg/m²)
N	257	142	40
Mean ± SD	27.48 ± 6.21	27.53 ± 5.58	28.32 ± 5.68	0.6	0.4
History of previous endocarditis
Previous endocarditis	16/280 (5.7%)	23/157 (14.6%)	4/46 (8.7%)	0.001	0.2
Type of microorganism
Staphylococcus aureus	6/12 (50.0%)	6/15 (40.0%)	2/3 (66.7%)	0.6	0.5
Methi-S Staphylococcus aureus	6/12 (50.0%)	5/15 (33.3%)	1/3 (33.3%)	0.4	>0.9
Chronic renal failure	71/280 (25.4%)	52/157 (33.1%)	14/46 (30.4%)	0.08	0.7
Diabetes mellitus	110/280 (39.3%)	51/157 (32.5%)	21/46 (45.7%)	0.1	0.1
Heart failure	114/245 (46.5%)	80/141 (56.7%)	14/43 (32.6%)	0.05	0.005
Charlson index
N	232	136	40
Mean ± SD	4.42 ± 3.16	5.41 ± 2.83	4.93 ± 2.04	<0.0001	0.3
Antithrombotic treatment on admission	206/274 (75.2%)	135/155 (87.1%)	40/45 (88.9%)	0.003	0.7
Device therapy
Pacemaker	150/280 (53.6%)	118/157 (75.2%)	28/46 (60.9%)	<0.0001	0.1
ICD (defibrillator)	84/280 (30.0%)	23/157 (14.6%)	8/46 (17.4%)
CRT-D (with ICD)	42/280 (15.0%)	11/157 (7.0%)	6/46 (13.0%)
CRT-P (pacing only)	4/280 (1.4%)	5/157 (3.2%)	4/46 (8.7%)

Table 1

Open in new tab

Demography and patient medical history in patients with device

	CDRIE+LHIE− (1) (n = 280)	LHIE+CDRIE− (2) (n = 157)	CDRIE+LHIE+ (3) (n = 46)	P-value (1) vs. (2)	P-value (2) vs. (3)
Demographic
Age (years)
N	280	157	46
Mean ± SD	66.69 ± 14.31	71.08 ± 13.59	70.22 ± 10.11	0.0002	0.1
Females	75/280 (26.8%)	39/157 (24.8%)	19/46 (41.3%)	0.6	0.02
Body mass index (kg/m²)
N	257	142	40
Mean ± SD	27.48 ± 6.21	27.53 ± 5.58	28.32 ± 5.68	0.6	0.4
History of previous endocarditis
Previous endocarditis	16/280 (5.7%)	23/157 (14.6%)	4/46 (8.7%)	0.001	0.2
Type of microorganism
Staphylococcus aureus	6/12 (50.0%)	6/15 (40.0%)	2/3 (66.7%)	0.6	0.5
Methi-S Staphylococcus aureus	6/12 (50.0%)	5/15 (33.3%)	1/3 (33.3%)	0.4	>0.9
Chronic renal failure	71/280 (25.4%)	52/157 (33.1%)	14/46 (30.4%)	0.08	0.7
Diabetes mellitus	110/280 (39.3%)	51/157 (32.5%)	21/46 (45.7%)	0.1	0.1
Heart failure	114/245 (46.5%)	80/141 (56.7%)	14/43 (32.6%)	0.05	0.005
Charlson index
N	232	136	40
Mean ± SD	4.42 ± 3.16	5.41 ± 2.83	4.93 ± 2.04	<0.0001	0.3
Antithrombotic treatment on admission	206/274 (75.2%)	135/155 (87.1%)	40/45 (88.9%)	0.003	0.7
Device therapy
Pacemaker	150/280 (53.6%)	118/157 (75.2%)	28/46 (60.9%)	<0.0001	0.1
ICD (defibrillator)	84/280 (30.0%)	23/157 (14.6%)	8/46 (17.4%)
CRT-D (with ICD)	42/280 (15.0%)	11/157 (7.0%)	6/46 (13.0%)
CRT-P (pacing only)	4/280 (1.4%)	5/157 (3.2%)	4/46 (8.7%)

	CDRIE+LHIE− (1) (n = 280)	LHIE+CDRIE− (2) (n = 157)	CDRIE+LHIE+ (3) (n = 46)	P-value (1) vs. (2)	P-value (2) vs. (3)
Demographic
Age (years)
N	280	157	46
Mean ± SD	66.69 ± 14.31	71.08 ± 13.59	70.22 ± 10.11	0.0002	0.1
Females	75/280 (26.8%)	39/157 (24.8%)	19/46 (41.3%)	0.6	0.02
Body mass index (kg/m²)
N	257	142	40
Mean ± SD	27.48 ± 6.21	27.53 ± 5.58	28.32 ± 5.68	0.6	0.4
History of previous endocarditis
Previous endocarditis	16/280 (5.7%)	23/157 (14.6%)	4/46 (8.7%)	0.001	0.2
Type of microorganism
Staphylococcus aureus	6/12 (50.0%)	6/15 (40.0%)	2/3 (66.7%)	0.6	0.5
Methi-S Staphylococcus aureus	6/12 (50.0%)	5/15 (33.3%)	1/3 (33.3%)	0.4	>0.9
Chronic renal failure	71/280 (25.4%)	52/157 (33.1%)	14/46 (30.4%)	0.08	0.7
Diabetes mellitus	110/280 (39.3%)	51/157 (32.5%)	21/46 (45.7%)	0.1	0.1
Heart failure	114/245 (46.5%)	80/141 (56.7%)	14/43 (32.6%)	0.05	0.005
Charlson index
N	232	136	40
Mean ± SD	4.42 ± 3.16	5.41 ± 2.83	4.93 ± 2.04	<0.0001	0.3
Antithrombotic treatment on admission	206/274 (75.2%)	135/155 (87.1%)	40/45 (88.9%)	0.003	0.7
Device therapy
Pacemaker	150/280 (53.6%)	118/157 (75.2%)	28/46 (60.9%)	<0.0001	0.1
ICD (defibrillator)	84/280 (30.0%)	23/157 (14.6%)	8/46 (17.4%)
CRT-D (with ICD)	42/280 (15.0%)	11/157 (7.0%)	6/46 (13.0%)
CRT-P (pacing only)	4/280 (1.4%)	5/157 (3.2%)	4/46 (8.7%)

CDRIE+ corresponds to patient with at least the infective endocarditis is on ICD/PM only or on ICD/PM+ (pulmonary or tricuspid). CDRIE− corresponds to patient with device and without CDRIE or pulmonary or tricuspid location of IE. Kruskal–Wallis test is used for quantitative data. χ² or Fisher’s exact test [a] is used for binary variables.

CRT, cardiac resynchronization therapy; ICD, implantable cardioverter-defibrillator; LHIE+, left heart infective endocarditis; LHIE−, no left heart infective endocarditis.

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