Systemic iron status 24 weeks after MI or sham surgery and saline or FCM injections
| . | Sham . | MI . | ||
|---|---|---|---|---|
| Saline (n = 10) . | FCM (n = 10) . | Saline (n = 10) . | FCM (n = 10) . | |
| Haemoglobin (g/dL) | 16.1 (15.8–17.5) | 16.1 (15.6–17.2) | 16.8 (16.2–17.9) | 16.8 (15.7–18.2) |
| Plasma iron (µmol/L) | 17.9 (15.7–19.3) | 18.6 (13.4–19.6) | 15.5 (13.1–18.7) | 17.9 (12.8–21.3) |
| TSAT (%) | 31.4 (29.3–32.9) | 28.2 (22.7–36.2) | 27.8 (24.3–31.6) | 30.1 (21.6–43.4) |
| Plasma ferritin (µg/L) | 259 (204–302) | 1234 (1014–1415)*** | 277 (214–335) | 1303 (1085–1471)*** |
| . | Sham . | MI . | ||
|---|---|---|---|---|
| Saline (n = 10) . | FCM (n = 10) . | Saline (n = 10) . | FCM (n = 10) . | |
| Haemoglobin (g/dL) | 16.1 (15.8–17.5) | 16.1 (15.6–17.2) | 16.8 (16.2–17.9) | 16.8 (15.7–18.2) |
| Plasma iron (µmol/L) | 17.9 (15.7–19.3) | 18.6 (13.4–19.6) | 15.5 (13.1–18.7) | 17.9 (12.8–21.3) |
| TSAT (%) | 31.4 (29.3–32.9) | 28.2 (22.7–36.2) | 27.8 (24.3–31.6) | 30.1 (21.6–43.4) |
| Plasma ferritin (µg/L) | 259 (204–302) | 1234 (1014–1415)*** | 277 (214–335) | 1303 (1085–1471)*** |
Twelve weeks after sham or MI surgery, mice were randomized and treated with intravenous FCM (15 µg/g body weight) or saline at 12, 16, and 20 weeks. Blood analyses were performed at 24 weeks.
TSAT, transferrin saturation.
P < 0.001 (FCM vs. saline in sham and MI groups); Mann–Whitney U test.
Systemic iron status 24 weeks after MI or sham surgery and saline or FCM injections
| . | Sham . | MI . | ||
|---|---|---|---|---|
| Saline (n = 10) . | FCM (n = 10) . | Saline (n = 10) . | FCM (n = 10) . | |
| Haemoglobin (g/dL) | 16.1 (15.8–17.5) | 16.1 (15.6–17.2) | 16.8 (16.2–17.9) | 16.8 (15.7–18.2) |
| Plasma iron (µmol/L) | 17.9 (15.7–19.3) | 18.6 (13.4–19.6) | 15.5 (13.1–18.7) | 17.9 (12.8–21.3) |
| TSAT (%) | 31.4 (29.3–32.9) | 28.2 (22.7–36.2) | 27.8 (24.3–31.6) | 30.1 (21.6–43.4) |
| Plasma ferritin (µg/L) | 259 (204–302) | 1234 (1014–1415)*** | 277 (214–335) | 1303 (1085–1471)*** |
| . | Sham . | MI . | ||
|---|---|---|---|---|
| Saline (n = 10) . | FCM (n = 10) . | Saline (n = 10) . | FCM (n = 10) . | |
| Haemoglobin (g/dL) | 16.1 (15.8–17.5) | 16.1 (15.6–17.2) | 16.8 (16.2–17.9) | 16.8 (15.7–18.2) |
| Plasma iron (µmol/L) | 17.9 (15.7–19.3) | 18.6 (13.4–19.6) | 15.5 (13.1–18.7) | 17.9 (12.8–21.3) |
| TSAT (%) | 31.4 (29.3–32.9) | 28.2 (22.7–36.2) | 27.8 (24.3–31.6) | 30.1 (21.6–43.4) |
| Plasma ferritin (µg/L) | 259 (204–302) | 1234 (1014–1415)*** | 277 (214–335) | 1303 (1085–1471)*** |
Twelve weeks after sham or MI surgery, mice were randomized and treated with intravenous FCM (15 µg/g body weight) or saline at 12, 16, and 20 weeks. Blood analyses were performed at 24 weeks.
TSAT, transferrin saturation.
P < 0.001 (FCM vs. saline in sham and MI groups); Mann–Whitney U test.
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