Aortic valve stenosis and left ventricular characterization at pre-operative echo and CMR study
| Total study population: n = 158 . | |
|---|---|
| Aortic valve characterization—TTEa | |
| Mean aortic gradient, mmHg | 60.9 ± 17.4 |
| Aortic valve area, cm2 | 0.72 ± 0.17 |
| LV adaptation—TTE and CMR (patients with complete pre-operative CMR: n = 143) | |
| Stroke volume index, mL/m2 | 47.2 ± 10.7 |
| Relative wall thickness | 0.53 ± 0.12 |
| LV ejection fraction, % | 58.2 ± 9.2 |
| Maximum septal thickness (echo), mm | 16.0 ± 2.6 |
| Global longitudinal strain at echo, % | 14.9 ± 3.6 |
| LV mass by CMR, g | 145.2 ± 51.7 |
| LV indexed mass by CMR, g/m2 | 79.3 ± 25.9 |
| LV telediastolic indexed volume, mL/m2 | 65.9 ± 33.0 |
| Geometric remodelling, g/mL | 0.95 (0.82–1.06) |
| LV ejection fraction by CMR, % | 59.4 ± 10.3 |
| Tissue characterization (patients with complete pre-operative CMR: n = 143) | |
| Global native T1, ms | 1053 (1024–1071) |
| Septal native T1, ms | 1074 (1046–1103) |
| Global native T2, ms | 39.3 (37.3–42.0) |
| Septal native T2, ms | 41.4 (38.7–43.6) |
| T2*, ms | 30.6 (26.1–35.5) |
| Global ECV, % | 23.0 (20.0–27.0) |
| Septal ECV, % | 23.0 (19.0–26.0) |
| LGE, n | 106 (67.1%) |
| Junctional LGE, n | 26 (16.5%) |
| LGE mass, % | 5.0 (2.0–9.7) |
| Total study population: n = 158 . | |
|---|---|
| Aortic valve characterization—TTEa | |
| Mean aortic gradient, mmHg | 60.9 ± 17.4 |
| Aortic valve area, cm2 | 0.72 ± 0.17 |
| LV adaptation—TTE and CMR (patients with complete pre-operative CMR: n = 143) | |
| Stroke volume index, mL/m2 | 47.2 ± 10.7 |
| Relative wall thickness | 0.53 ± 0.12 |
| LV ejection fraction, % | 58.2 ± 9.2 |
| Maximum septal thickness (echo), mm | 16.0 ± 2.6 |
| Global longitudinal strain at echo, % | 14.9 ± 3.6 |
| LV mass by CMR, g | 145.2 ± 51.7 |
| LV indexed mass by CMR, g/m2 | 79.3 ± 25.9 |
| LV telediastolic indexed volume, mL/m2 | 65.9 ± 33.0 |
| Geometric remodelling, g/mL | 0.95 (0.82–1.06) |
| LV ejection fraction by CMR, % | 59.4 ± 10.3 |
| Tissue characterization (patients with complete pre-operative CMR: n = 143) | |
| Global native T1, ms | 1053 (1024–1071) |
| Septal native T1, ms | 1074 (1046–1103) |
| Global native T2, ms | 39.3 (37.3–42.0) |
| Septal native T2, ms | 41.4 (38.7–43.6) |
| T2*, ms | 30.6 (26.1–35.5) |
| Global ECV, % | 23.0 (20.0–27.0) |
| Septal ECV, % | 23.0 (19.0–26.0) |
| LGE, n | 106 (67.1%) |
| Junctional LGE, n | 26 (16.5%) |
| LGE mass, % | 5.0 (2.0–9.7) |
Values are median (interquartile range), mean ± standard deviation.
CMR, cardiac magnetic resonance; ECV, extracellular volume, geometric remodelling: LV mass/LV end-diastolic volume; LGE, late gadolinium enhancement; LV, left ventricle; TTE, transthoracic echocardiography.
aTrace or mild aortic valve regurgitation was present in 101 patients (63.9%).
Aortic valve stenosis and left ventricular characterization at pre-operative echo and CMR study
| Total study population: n = 158 . | |
|---|---|
| Aortic valve characterization—TTEa | |
| Mean aortic gradient, mmHg | 60.9 ± 17.4 |
| Aortic valve area, cm2 | 0.72 ± 0.17 |
| LV adaptation—TTE and CMR (patients with complete pre-operative CMR: n = 143) | |
| Stroke volume index, mL/m2 | 47.2 ± 10.7 |
| Relative wall thickness | 0.53 ± 0.12 |
| LV ejection fraction, % | 58.2 ± 9.2 |
| Maximum septal thickness (echo), mm | 16.0 ± 2.6 |
| Global longitudinal strain at echo, % | 14.9 ± 3.6 |
| LV mass by CMR, g | 145.2 ± 51.7 |
| LV indexed mass by CMR, g/m2 | 79.3 ± 25.9 |
| LV telediastolic indexed volume, mL/m2 | 65.9 ± 33.0 |
| Geometric remodelling, g/mL | 0.95 (0.82–1.06) |
| LV ejection fraction by CMR, % | 59.4 ± 10.3 |
| Tissue characterization (patients with complete pre-operative CMR: n = 143) | |
| Global native T1, ms | 1053 (1024–1071) |
| Septal native T1, ms | 1074 (1046–1103) |
| Global native T2, ms | 39.3 (37.3–42.0) |
| Septal native T2, ms | 41.4 (38.7–43.6) |
| T2*, ms | 30.6 (26.1–35.5) |
| Global ECV, % | 23.0 (20.0–27.0) |
| Septal ECV, % | 23.0 (19.0–26.0) |
| LGE, n | 106 (67.1%) |
| Junctional LGE, n | 26 (16.5%) |
| LGE mass, % | 5.0 (2.0–9.7) |
| Total study population: n = 158 . | |
|---|---|
| Aortic valve characterization—TTEa | |
| Mean aortic gradient, mmHg | 60.9 ± 17.4 |
| Aortic valve area, cm2 | 0.72 ± 0.17 |
| LV adaptation—TTE and CMR (patients with complete pre-operative CMR: n = 143) | |
| Stroke volume index, mL/m2 | 47.2 ± 10.7 |
| Relative wall thickness | 0.53 ± 0.12 |
| LV ejection fraction, % | 58.2 ± 9.2 |
| Maximum septal thickness (echo), mm | 16.0 ± 2.6 |
| Global longitudinal strain at echo, % | 14.9 ± 3.6 |
| LV mass by CMR, g | 145.2 ± 51.7 |
| LV indexed mass by CMR, g/m2 | 79.3 ± 25.9 |
| LV telediastolic indexed volume, mL/m2 | 65.9 ± 33.0 |
| Geometric remodelling, g/mL | 0.95 (0.82–1.06) |
| LV ejection fraction by CMR, % | 59.4 ± 10.3 |
| Tissue characterization (patients with complete pre-operative CMR: n = 143) | |
| Global native T1, ms | 1053 (1024–1071) |
| Septal native T1, ms | 1074 (1046–1103) |
| Global native T2, ms | 39.3 (37.3–42.0) |
| Septal native T2, ms | 41.4 (38.7–43.6) |
| T2*, ms | 30.6 (26.1–35.5) |
| Global ECV, % | 23.0 (20.0–27.0) |
| Septal ECV, % | 23.0 (19.0–26.0) |
| LGE, n | 106 (67.1%) |
| Junctional LGE, n | 26 (16.5%) |
| LGE mass, % | 5.0 (2.0–9.7) |
Values are median (interquartile range), mean ± standard deviation.
CMR, cardiac magnetic resonance; ECV, extracellular volume, geometric remodelling: LV mass/LV end-diastolic volume; LGE, late gadolinium enhancement; LV, left ventricle; TTE, transthoracic echocardiography.
aTrace or mild aortic valve regurgitation was present in 101 patients (63.9%).
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