Author, year . | Country . | Surgery type . | Cognitive test . | POCD assessment (day after surgery) . | POD assessment (%, day after surgery, tools) . | Age (years) . | Study size . | Outcomes . |
---|---|---|---|---|---|---|---|---|
Cardiac surgery | ||||||||
Boodhwani, 2006 [46] | Canada | Cardiac (on-pump CABG) | NP test | 7 | NA | 68.3 | 448 | LOS |
Hogue_1, 2008 [34] | USA | Cardiac (on-pump CABG and cardiac valve replacement) | NP test | 30 | NA | 70 | 174 | Function (180-day Modified Lawton’s Scale) |
Hogue, 2008 [48] | USA | Cardiac (on-pump CABG and cardiac valve replacement) | NP test | 30 | NA | 70 | 174 | LOS |
Liu, 2009 [45] | China | Cardiac (on-/off-pump CABG) | NP test | 7 | NA | 60 | 227 | LOS |
Norkiene, 2010 [49] | Lithuania | Cardiac (on-pump CABG) | NP test | 7 | 6.3%, NM, DSM IV | 60.9 | 127 | LOS |
Toeg, 2013 [41] | Canada | Cardiac (on-pump CABG) | NP test | 90 | NA | 64.4 | 696 | Mortality (90 days), LOS |
Benvenuti, 2014 [25] | Italy | Cardiac (on-pump CABG and cardiac valve replacement) | NP test | 7, 90 | NA | 63.8 | 79 | Function (90-day Adjusted Lawton Score) |
Evered, 2016 [6] | Australia | Cardiac (on-/off-pump CABG) | NP test | 90, 365 | NA | 68.0 | 326 | Mortality (7.5 years), dementia (7.5 years) |
Hayashi, 2018 [43] | Japan | Cardiac (on-pump CABG, cardiac valve replacement and thoracic aortic surgery) | MMSE | 14 | NA | 71.4 | 204 | LOS |
Momeni, 2019 [42] | Belgium | Cardiac (on-/off-pump CABG and TAVI) | MMSE | 5 | 20%, NM, Validated chart review method | 67.7 | 1513 | Mortality (180 days), LOS |
Tarasova, 2020 [32] | Russia | Cardiac (CABG) | NP test | 365 | NA | 57.3 | 100 | Function (1-year SF-36) |
Noncardiac surgery | ||||||||
Rodriguez, 2005 [47] | Canada | Noncardiac (TKA) | NP test | 7, 90 | 6.5%, NM, CAM | 69 | 31 | LOS |
Monk, 2008 [4] | USA | Noncardiac (47% abdominal or thoracic, 39% orthopaedic) | NP test | 7, 90 | 3.3%, Day 1–7, CAM | 50.6 | 1064 | Function (90-day IADL questionnaire), Mortality (1 year), LOS |
Steinmetz, 2009 [5] | Denmark | Noncardiac (56% abdominal, 20% orthopaedic) | NP test | 7, 90 | NA | 67.3 | 701 | Mortality (8.4 years) |
Steinmetz, 2013 [50] | Denmark | Noncardiac (56% abdominal, 20% orthopaedic) | NP test | 7, 90 | NA | 67.3 | 686 | Dementia (10 years) |
Krenk, 2014 [44] | Denmark | Noncardiac (THA and TKA) | NP test | 12 | -%, Day 1–3, DSM IV | 68.3 | 225 | LOS |
Franck, 2016 [40] | Germany | Noncardiac (38% abdominal or thoracic, 29% orthopaedic) | NP test | 7, 90 | 32.9%, Day 0–7, DSM IV-TR | 69.6 | 850 | Mortality (90 days), LOS |
Borges, 2017 [33] | Portugal | Noncardiac (49% abdominal, 15% plastic) | MoCA | 90 | NA | 63.7 | 41 | Function (90-day SF-36) |
Deiner, 2021 [7] | USA | Noncardiac (43% spine, 29% general) | NP test | 90 | 25.3%, NM, CAM-ICU | 70 | 167 | Function (90-day ADCS-ADL-MCI), LOS |
Mixed cardiac and noncardiac surgeries | ||||||||
Suraarunsumrit, 2022 [8] | Thailand | Cardiac (on-pump CABG and cardiac valve replacement) | MoCA | 7 | 20.4%, Day 1–7, DSM-5 | 69.9 | 119 | Function (90-day Lawton–Brody-IADL), mortality (90 days), LOS |
Noncardiac (42% orthopaedic, 27.3% abdominal) | MoCA | 7 | 6.6%, Day 1–7, DSM-5 | 75.7 | 88 | Function (90-day Lawton–Brody-IADL), mortality (90 days), LOS |
Author, year . | Country . | Surgery type . | Cognitive test . | POCD assessment (day after surgery) . | POD assessment (%, day after surgery, tools) . | Age (years) . | Study size . | Outcomes . |
---|---|---|---|---|---|---|---|---|
Cardiac surgery | ||||||||
Boodhwani, 2006 [46] | Canada | Cardiac (on-pump CABG) | NP test | 7 | NA | 68.3 | 448 | LOS |
Hogue_1, 2008 [34] | USA | Cardiac (on-pump CABG and cardiac valve replacement) | NP test | 30 | NA | 70 | 174 | Function (180-day Modified Lawton’s Scale) |
Hogue, 2008 [48] | USA | Cardiac (on-pump CABG and cardiac valve replacement) | NP test | 30 | NA | 70 | 174 | LOS |
Liu, 2009 [45] | China | Cardiac (on-/off-pump CABG) | NP test | 7 | NA | 60 | 227 | LOS |
Norkiene, 2010 [49] | Lithuania | Cardiac (on-pump CABG) | NP test | 7 | 6.3%, NM, DSM IV | 60.9 | 127 | LOS |
Toeg, 2013 [41] | Canada | Cardiac (on-pump CABG) | NP test | 90 | NA | 64.4 | 696 | Mortality (90 days), LOS |
Benvenuti, 2014 [25] | Italy | Cardiac (on-pump CABG and cardiac valve replacement) | NP test | 7, 90 | NA | 63.8 | 79 | Function (90-day Adjusted Lawton Score) |
Evered, 2016 [6] | Australia | Cardiac (on-/off-pump CABG) | NP test | 90, 365 | NA | 68.0 | 326 | Mortality (7.5 years), dementia (7.5 years) |
Hayashi, 2018 [43] | Japan | Cardiac (on-pump CABG, cardiac valve replacement and thoracic aortic surgery) | MMSE | 14 | NA | 71.4 | 204 | LOS |
Momeni, 2019 [42] | Belgium | Cardiac (on-/off-pump CABG and TAVI) | MMSE | 5 | 20%, NM, Validated chart review method | 67.7 | 1513 | Mortality (180 days), LOS |
Tarasova, 2020 [32] | Russia | Cardiac (CABG) | NP test | 365 | NA | 57.3 | 100 | Function (1-year SF-36) |
Noncardiac surgery | ||||||||
Rodriguez, 2005 [47] | Canada | Noncardiac (TKA) | NP test | 7, 90 | 6.5%, NM, CAM | 69 | 31 | LOS |
Monk, 2008 [4] | USA | Noncardiac (47% abdominal or thoracic, 39% orthopaedic) | NP test | 7, 90 | 3.3%, Day 1–7, CAM | 50.6 | 1064 | Function (90-day IADL questionnaire), Mortality (1 year), LOS |
Steinmetz, 2009 [5] | Denmark | Noncardiac (56% abdominal, 20% orthopaedic) | NP test | 7, 90 | NA | 67.3 | 701 | Mortality (8.4 years) |
Steinmetz, 2013 [50] | Denmark | Noncardiac (56% abdominal, 20% orthopaedic) | NP test | 7, 90 | NA | 67.3 | 686 | Dementia (10 years) |
Krenk, 2014 [44] | Denmark | Noncardiac (THA and TKA) | NP test | 12 | -%, Day 1–3, DSM IV | 68.3 | 225 | LOS |
Franck, 2016 [40] | Germany | Noncardiac (38% abdominal or thoracic, 29% orthopaedic) | NP test | 7, 90 | 32.9%, Day 0–7, DSM IV-TR | 69.6 | 850 | Mortality (90 days), LOS |
Borges, 2017 [33] | Portugal | Noncardiac (49% abdominal, 15% plastic) | MoCA | 90 | NA | 63.7 | 41 | Function (90-day SF-36) |
Deiner, 2021 [7] | USA | Noncardiac (43% spine, 29% general) | NP test | 90 | 25.3%, NM, CAM-ICU | 70 | 167 | Function (90-day ADCS-ADL-MCI), LOS |
Mixed cardiac and noncardiac surgeries | ||||||||
Suraarunsumrit, 2022 [8] | Thailand | Cardiac (on-pump CABG and cardiac valve replacement) | MoCA | 7 | 20.4%, Day 1–7, DSM-5 | 69.9 | 119 | Function (90-day Lawton–Brody-IADL), mortality (90 days), LOS |
Noncardiac (42% orthopaedic, 27.3% abdominal) | MoCA | 7 | 6.6%, Day 1–7, DSM-5 | 75.7 | 88 | Function (90-day Lawton–Brody-IADL), mortality (90 days), LOS |
All are prospective cohort studies; ADCS-ADL-MCI, Alzheimer’s disease cooperative study/activities of daily living scale, adapted for patients with mild cognitive impairment; CABG, coronary artery bypass graft; CAM, Confusion Assessment Method; CAM-ICU, Confusion Assessment Method for the intensive care unit; DSM IV, Diagnostic and Statistical Manual of Mental Disorders, fourth edition; DSM IV-TR, Diagnostic and Statistical Manual of Mental Disorders, fourth edition, text revision; DSM-5, Diagnostic and Statistical Manual of Mental Disorders, fifth edition; IADL, Instrumental activities of daily living; LOS, length of hospital stay; MMSE, Mini-Mental State Examination score; MoCA, Montreal Cognitive Assessment Test; NA, not available data; NM, not mentioned postoperative day; NP test, neuropsychological test battery; POCD, postoperative cognitive dysfunction; RCI, reliable change index methods; SD, standard deviation; SF-36, 36-Item Short Form Survey; TAVI, transcatheter aortic valve implantation; THA, total hip arthroplasty; TKA, total knee arthroplasty.
Author, year . | Country . | Surgery type . | Cognitive test . | POCD assessment (day after surgery) . | POD assessment (%, day after surgery, tools) . | Age (years) . | Study size . | Outcomes . |
---|---|---|---|---|---|---|---|---|
Cardiac surgery | ||||||||
Boodhwani, 2006 [46] | Canada | Cardiac (on-pump CABG) | NP test | 7 | NA | 68.3 | 448 | LOS |
Hogue_1, 2008 [34] | USA | Cardiac (on-pump CABG and cardiac valve replacement) | NP test | 30 | NA | 70 | 174 | Function (180-day Modified Lawton’s Scale) |
Hogue, 2008 [48] | USA | Cardiac (on-pump CABG and cardiac valve replacement) | NP test | 30 | NA | 70 | 174 | LOS |
Liu, 2009 [45] | China | Cardiac (on-/off-pump CABG) | NP test | 7 | NA | 60 | 227 | LOS |
Norkiene, 2010 [49] | Lithuania | Cardiac (on-pump CABG) | NP test | 7 | 6.3%, NM, DSM IV | 60.9 | 127 | LOS |
Toeg, 2013 [41] | Canada | Cardiac (on-pump CABG) | NP test | 90 | NA | 64.4 | 696 | Mortality (90 days), LOS |
Benvenuti, 2014 [25] | Italy | Cardiac (on-pump CABG and cardiac valve replacement) | NP test | 7, 90 | NA | 63.8 | 79 | Function (90-day Adjusted Lawton Score) |
Evered, 2016 [6] | Australia | Cardiac (on-/off-pump CABG) | NP test | 90, 365 | NA | 68.0 | 326 | Mortality (7.5 years), dementia (7.5 years) |
Hayashi, 2018 [43] | Japan | Cardiac (on-pump CABG, cardiac valve replacement and thoracic aortic surgery) | MMSE | 14 | NA | 71.4 | 204 | LOS |
Momeni, 2019 [42] | Belgium | Cardiac (on-/off-pump CABG and TAVI) | MMSE | 5 | 20%, NM, Validated chart review method | 67.7 | 1513 | Mortality (180 days), LOS |
Tarasova, 2020 [32] | Russia | Cardiac (CABG) | NP test | 365 | NA | 57.3 | 100 | Function (1-year SF-36) |
Noncardiac surgery | ||||||||
Rodriguez, 2005 [47] | Canada | Noncardiac (TKA) | NP test | 7, 90 | 6.5%, NM, CAM | 69 | 31 | LOS |
Monk, 2008 [4] | USA | Noncardiac (47% abdominal or thoracic, 39% orthopaedic) | NP test | 7, 90 | 3.3%, Day 1–7, CAM | 50.6 | 1064 | Function (90-day IADL questionnaire), Mortality (1 year), LOS |
Steinmetz, 2009 [5] | Denmark | Noncardiac (56% abdominal, 20% orthopaedic) | NP test | 7, 90 | NA | 67.3 | 701 | Mortality (8.4 years) |
Steinmetz, 2013 [50] | Denmark | Noncardiac (56% abdominal, 20% orthopaedic) | NP test | 7, 90 | NA | 67.3 | 686 | Dementia (10 years) |
Krenk, 2014 [44] | Denmark | Noncardiac (THA and TKA) | NP test | 12 | -%, Day 1–3, DSM IV | 68.3 | 225 | LOS |
Franck, 2016 [40] | Germany | Noncardiac (38% abdominal or thoracic, 29% orthopaedic) | NP test | 7, 90 | 32.9%, Day 0–7, DSM IV-TR | 69.6 | 850 | Mortality (90 days), LOS |
Borges, 2017 [33] | Portugal | Noncardiac (49% abdominal, 15% plastic) | MoCA | 90 | NA | 63.7 | 41 | Function (90-day SF-36) |
Deiner, 2021 [7] | USA | Noncardiac (43% spine, 29% general) | NP test | 90 | 25.3%, NM, CAM-ICU | 70 | 167 | Function (90-day ADCS-ADL-MCI), LOS |
Mixed cardiac and noncardiac surgeries | ||||||||
Suraarunsumrit, 2022 [8] | Thailand | Cardiac (on-pump CABG and cardiac valve replacement) | MoCA | 7 | 20.4%, Day 1–7, DSM-5 | 69.9 | 119 | Function (90-day Lawton–Brody-IADL), mortality (90 days), LOS |
Noncardiac (42% orthopaedic, 27.3% abdominal) | MoCA | 7 | 6.6%, Day 1–7, DSM-5 | 75.7 | 88 | Function (90-day Lawton–Brody-IADL), mortality (90 days), LOS |
Author, year . | Country . | Surgery type . | Cognitive test . | POCD assessment (day after surgery) . | POD assessment (%, day after surgery, tools) . | Age (years) . | Study size . | Outcomes . |
---|---|---|---|---|---|---|---|---|
Cardiac surgery | ||||||||
Boodhwani, 2006 [46] | Canada | Cardiac (on-pump CABG) | NP test | 7 | NA | 68.3 | 448 | LOS |
Hogue_1, 2008 [34] | USA | Cardiac (on-pump CABG and cardiac valve replacement) | NP test | 30 | NA | 70 | 174 | Function (180-day Modified Lawton’s Scale) |
Hogue, 2008 [48] | USA | Cardiac (on-pump CABG and cardiac valve replacement) | NP test | 30 | NA | 70 | 174 | LOS |
Liu, 2009 [45] | China | Cardiac (on-/off-pump CABG) | NP test | 7 | NA | 60 | 227 | LOS |
Norkiene, 2010 [49] | Lithuania | Cardiac (on-pump CABG) | NP test | 7 | 6.3%, NM, DSM IV | 60.9 | 127 | LOS |
Toeg, 2013 [41] | Canada | Cardiac (on-pump CABG) | NP test | 90 | NA | 64.4 | 696 | Mortality (90 days), LOS |
Benvenuti, 2014 [25] | Italy | Cardiac (on-pump CABG and cardiac valve replacement) | NP test | 7, 90 | NA | 63.8 | 79 | Function (90-day Adjusted Lawton Score) |
Evered, 2016 [6] | Australia | Cardiac (on-/off-pump CABG) | NP test | 90, 365 | NA | 68.0 | 326 | Mortality (7.5 years), dementia (7.5 years) |
Hayashi, 2018 [43] | Japan | Cardiac (on-pump CABG, cardiac valve replacement and thoracic aortic surgery) | MMSE | 14 | NA | 71.4 | 204 | LOS |
Momeni, 2019 [42] | Belgium | Cardiac (on-/off-pump CABG and TAVI) | MMSE | 5 | 20%, NM, Validated chart review method | 67.7 | 1513 | Mortality (180 days), LOS |
Tarasova, 2020 [32] | Russia | Cardiac (CABG) | NP test | 365 | NA | 57.3 | 100 | Function (1-year SF-36) |
Noncardiac surgery | ||||||||
Rodriguez, 2005 [47] | Canada | Noncardiac (TKA) | NP test | 7, 90 | 6.5%, NM, CAM | 69 | 31 | LOS |
Monk, 2008 [4] | USA | Noncardiac (47% abdominal or thoracic, 39% orthopaedic) | NP test | 7, 90 | 3.3%, Day 1–7, CAM | 50.6 | 1064 | Function (90-day IADL questionnaire), Mortality (1 year), LOS |
Steinmetz, 2009 [5] | Denmark | Noncardiac (56% abdominal, 20% orthopaedic) | NP test | 7, 90 | NA | 67.3 | 701 | Mortality (8.4 years) |
Steinmetz, 2013 [50] | Denmark | Noncardiac (56% abdominal, 20% orthopaedic) | NP test | 7, 90 | NA | 67.3 | 686 | Dementia (10 years) |
Krenk, 2014 [44] | Denmark | Noncardiac (THA and TKA) | NP test | 12 | -%, Day 1–3, DSM IV | 68.3 | 225 | LOS |
Franck, 2016 [40] | Germany | Noncardiac (38% abdominal or thoracic, 29% orthopaedic) | NP test | 7, 90 | 32.9%, Day 0–7, DSM IV-TR | 69.6 | 850 | Mortality (90 days), LOS |
Borges, 2017 [33] | Portugal | Noncardiac (49% abdominal, 15% plastic) | MoCA | 90 | NA | 63.7 | 41 | Function (90-day SF-36) |
Deiner, 2021 [7] | USA | Noncardiac (43% spine, 29% general) | NP test | 90 | 25.3%, NM, CAM-ICU | 70 | 167 | Function (90-day ADCS-ADL-MCI), LOS |
Mixed cardiac and noncardiac surgeries | ||||||||
Suraarunsumrit, 2022 [8] | Thailand | Cardiac (on-pump CABG and cardiac valve replacement) | MoCA | 7 | 20.4%, Day 1–7, DSM-5 | 69.9 | 119 | Function (90-day Lawton–Brody-IADL), mortality (90 days), LOS |
Noncardiac (42% orthopaedic, 27.3% abdominal) | MoCA | 7 | 6.6%, Day 1–7, DSM-5 | 75.7 | 88 | Function (90-day Lawton–Brody-IADL), mortality (90 days), LOS |
All are prospective cohort studies; ADCS-ADL-MCI, Alzheimer’s disease cooperative study/activities of daily living scale, adapted for patients with mild cognitive impairment; CABG, coronary artery bypass graft; CAM, Confusion Assessment Method; CAM-ICU, Confusion Assessment Method for the intensive care unit; DSM IV, Diagnostic and Statistical Manual of Mental Disorders, fourth edition; DSM IV-TR, Diagnostic and Statistical Manual of Mental Disorders, fourth edition, text revision; DSM-5, Diagnostic and Statistical Manual of Mental Disorders, fifth edition; IADL, Instrumental activities of daily living; LOS, length of hospital stay; MMSE, Mini-Mental State Examination score; MoCA, Montreal Cognitive Assessment Test; NA, not available data; NM, not mentioned postoperative day; NP test, neuropsychological test battery; POCD, postoperative cognitive dysfunction; RCI, reliable change index methods; SD, standard deviation; SF-36, 36-Item Short Form Survey; TAVI, transcatheter aortic valve implantation; THA, total hip arthroplasty; TKA, total knee arthroplasty.
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