Table 1.

Reported Indications for Breast-Specific Gamma Imaging

IndicationN = 440 (%)
Developing asymmetry or global asymmetry without prior comparison, intermediate risk, and inconclusive findings on diagnostic mammography and US209 (47.5)
Multiple low-suspicion masses with variable features (often in the setting of dense breast tissue, intermediate risk, and inconclusive findings on diagnostic mammography and US)105 (23.9)
Multiple bilateral low-suspicion regional calcifications without definite mass or dominant suspicious grouping to optimize targeting for biopsy40 (9.1)
Dense breast tissue, high anxiety, intermediate risk, complex baseline25 (5.7)
Suspicion following nonconcordant biopsy13 (3.0)
Outside referral, high clinical concern despite negative imaging findings14 (3.2)
Concern for radiologic-pathologic discordance and/or possible sampling error11 (2.5)
Extent of disease in the setting of a new cancer, MRI contraindicated7 (1.6)
Family history of breast cancer, high risk6 (1.4)
Known breast cancer, follow-up to therapy4 (0.9)
Concerning changes too close to an implant to enable image-guided biopsy3 (0.7)
Unusually high risk of bleeding from biopsy3 (0.7)
IndicationN = 440 (%)
Developing asymmetry or global asymmetry without prior comparison, intermediate risk, and inconclusive findings on diagnostic mammography and US209 (47.5)
Multiple low-suspicion masses with variable features (often in the setting of dense breast tissue, intermediate risk, and inconclusive findings on diagnostic mammography and US)105 (23.9)
Multiple bilateral low-suspicion regional calcifications without definite mass or dominant suspicious grouping to optimize targeting for biopsy40 (9.1)
Dense breast tissue, high anxiety, intermediate risk, complex baseline25 (5.7)
Suspicion following nonconcordant biopsy13 (3.0)
Outside referral, high clinical concern despite negative imaging findings14 (3.2)
Concern for radiologic-pathologic discordance and/or possible sampling error11 (2.5)
Extent of disease in the setting of a new cancer, MRI contraindicated7 (1.6)
Family history of breast cancer, high risk6 (1.4)
Known breast cancer, follow-up to therapy4 (0.9)
Concerning changes too close to an implant to enable image-guided biopsy3 (0.7)
Unusually high risk of bleeding from biopsy3 (0.7)
Table 1.

Reported Indications for Breast-Specific Gamma Imaging

IndicationN = 440 (%)
Developing asymmetry or global asymmetry without prior comparison, intermediate risk, and inconclusive findings on diagnostic mammography and US209 (47.5)
Multiple low-suspicion masses with variable features (often in the setting of dense breast tissue, intermediate risk, and inconclusive findings on diagnostic mammography and US)105 (23.9)
Multiple bilateral low-suspicion regional calcifications without definite mass or dominant suspicious grouping to optimize targeting for biopsy40 (9.1)
Dense breast tissue, high anxiety, intermediate risk, complex baseline25 (5.7)
Suspicion following nonconcordant biopsy13 (3.0)
Outside referral, high clinical concern despite negative imaging findings14 (3.2)
Concern for radiologic-pathologic discordance and/or possible sampling error11 (2.5)
Extent of disease in the setting of a new cancer, MRI contraindicated7 (1.6)
Family history of breast cancer, high risk6 (1.4)
Known breast cancer, follow-up to therapy4 (0.9)
Concerning changes too close to an implant to enable image-guided biopsy3 (0.7)
Unusually high risk of bleeding from biopsy3 (0.7)
IndicationN = 440 (%)
Developing asymmetry or global asymmetry without prior comparison, intermediate risk, and inconclusive findings on diagnostic mammography and US209 (47.5)
Multiple low-suspicion masses with variable features (often in the setting of dense breast tissue, intermediate risk, and inconclusive findings on diagnostic mammography and US)105 (23.9)
Multiple bilateral low-suspicion regional calcifications without definite mass or dominant suspicious grouping to optimize targeting for biopsy40 (9.1)
Dense breast tissue, high anxiety, intermediate risk, complex baseline25 (5.7)
Suspicion following nonconcordant biopsy13 (3.0)
Outside referral, high clinical concern despite negative imaging findings14 (3.2)
Concern for radiologic-pathologic discordance and/or possible sampling error11 (2.5)
Extent of disease in the setting of a new cancer, MRI contraindicated7 (1.6)
Family history of breast cancer, high risk6 (1.4)
Known breast cancer, follow-up to therapy4 (0.9)
Concerning changes too close to an implant to enable image-guided biopsy3 (0.7)
Unusually high risk of bleeding from biopsy3 (0.7)
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