Table 5.

Middle-exclusion effect on a neural network trained to classify lncRNA. The network architecture was an MLP. The features were k-mer profiles of RNA sequences. The data, features and training regimes were as in previous tables. The middle exclusion filter was applied to (A) all the data, (B) none of the data, (C) the training subsets only or (D) the validation subsets only

ABCD
Train filter: validation filter:Middle excl. middle excl.None noneMiddle excl. noneNone middle excl.
Accuracy68.7 ± 262.2 ± 361.7 ± 170.9 ± 2
F163.0 ± 360.1 ± 461.3 ± 170.7 ± 2
MCC0.3900.2540.2360.419
AUPRC78.7 ± 168.0 ± 366.4 ± 278.4 ± 2
AUROC77.2 ± 167.8 ± 366.1 ± 177.6 ± 2
ABCD
Train filter: validation filter:Middle excl. middle excl.None noneMiddle excl. noneNone middle excl.
Accuracy68.7 ± 262.2 ± 361.7 ± 170.9 ± 2
F163.0 ± 360.1 ± 461.3 ± 170.7 ± 2
MCC0.3900.2540.2360.419
AUPRC78.7 ± 168.0 ± 366.4 ± 278.4 ± 2
AUROC77.2 ± 167.8 ± 366.1 ± 177.6 ± 2
Table 5.

Middle-exclusion effect on a neural network trained to classify lncRNA. The network architecture was an MLP. The features were k-mer profiles of RNA sequences. The data, features and training regimes were as in previous tables. The middle exclusion filter was applied to (A) all the data, (B) none of the data, (C) the training subsets only or (D) the validation subsets only

ABCD
Train filter: validation filter:Middle excl. middle excl.None noneMiddle excl. noneNone middle excl.
Accuracy68.7 ± 262.2 ± 361.7 ± 170.9 ± 2
F163.0 ± 360.1 ± 461.3 ± 170.7 ± 2
MCC0.3900.2540.2360.419
AUPRC78.7 ± 168.0 ± 366.4 ± 278.4 ± 2
AUROC77.2 ± 167.8 ± 366.1 ± 177.6 ± 2
ABCD
Train filter: validation filter:Middle excl. middle excl.None noneMiddle excl. noneNone middle excl.
Accuracy68.7 ± 262.2 ± 361.7 ± 170.9 ± 2
F163.0 ± 360.1 ± 461.3 ± 170.7 ± 2
MCC0.3900.2540.2360.419
AUPRC78.7 ± 168.0 ± 366.4 ± 278.4 ± 2
AUROC77.2 ± 167.8 ± 366.1 ± 177.6 ± 2
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