Table 1.

Baseline characteristics (N = 481).

All patients (N = 481)CDP (n = 47)No CDP (n = 434)P valueMissing
Postoperative follow-up, y6.2 (2.3-13.5)22.9 (12.1-27.4)5.4 (2.0-11.9)<.01a0 (0)
Female236 (49)19 (40)217 (50).2120 (0)
Diagnosis before colectomy.7980 (0)
 UC468 (97)46 (98)422 (97)
 IBD-U13 (3)1 (2)12 (27)
Age at diagnosis, y28.7 (20.6-37.6)24.6 (18.8-32.3)29.5 (20.7-38.0).036a60 (12)
Disease duration at time of colectomy, y4.1 (1.5-8.0)3.3 (1.2-5.8)4.1 (1.5-8.3).12662 (13)
Histology report resection specimenb.05194 (19)
 Fitting UC289 (60)29 (62)260 (60)
 Indeterminate63 (13)5 (11)58 (13)
 Fitting CD35 (7)8 (17)27 (6)
Colectomy setting.96374 (15)
 Elective253 (53)25 (53)228 (53)
 (Semi)urgent154 (32)15 (32)139 (32)
Age at time of IPAA y35.9 (27.9-44.7)30.3 (23.3-38.4)36.7 (28.4-45.4)<.01a0 (0)
Stages IPAA surgery.7373 (1)
 1140 (29)15 (32)125 (29)
 280 (17)10 (21)70 (16)
 Modified 2213 (44)18 (38)195 (45)
 345 (9)4 (9)41 (9)
Smoking.345149 (31)
 No260 (54)14 (30)246 (57)
 Previously25 (5)3 (6)22 (5)
 Yes47 (10)4 (9)43 (10)
Pouch excision during follow-up18 (4)6 (13)12 (3)<.01a0 (0)
All patients (N = 481)CDP (n = 47)No CDP (n = 434)P valueMissing
Postoperative follow-up, y6.2 (2.3-13.5)22.9 (12.1-27.4)5.4 (2.0-11.9)<.01a0 (0)
Female236 (49)19 (40)217 (50).2120 (0)
Diagnosis before colectomy.7980 (0)
 UC468 (97)46 (98)422 (97)
 IBD-U13 (3)1 (2)12 (27)
Age at diagnosis, y28.7 (20.6-37.6)24.6 (18.8-32.3)29.5 (20.7-38.0).036a60 (12)
Disease duration at time of colectomy, y4.1 (1.5-8.0)3.3 (1.2-5.8)4.1 (1.5-8.3).12662 (13)
Histology report resection specimenb.05194 (19)
 Fitting UC289 (60)29 (62)260 (60)
 Indeterminate63 (13)5 (11)58 (13)
 Fitting CD35 (7)8 (17)27 (6)
Colectomy setting.96374 (15)
 Elective253 (53)25 (53)228 (53)
 (Semi)urgent154 (32)15 (32)139 (32)
Age at time of IPAA y35.9 (27.9-44.7)30.3 (23.3-38.4)36.7 (28.4-45.4)<.01a0 (0)
Stages IPAA surgery.7373 (1)
 1140 (29)15 (32)125 (29)
 280 (17)10 (21)70 (16)
 Modified 2213 (44)18 (38)195 (45)
 345 (9)4 (9)41 (9)
Smoking.345149 (31)
 No260 (54)14 (30)246 (57)
 Previously25 (5)3 (6)22 (5)
 Yes47 (10)4 (9)43 (10)
Pouch excision during follow-up18 (4)6 (13)12 (3)<.01a0 (0)

Values are median (interquartile range) or n (%).

Abbreviations: CD, Crohn’s disease; CDP, Crohn’s disease of the pouch; IBD-U, inflammatory bowel disease unclassified; IPAA, ileal pouch–anal anastomosis; UC, ulcerative colitis.

aDenotes that P value reaches statistical significance.

bDerived from colonic (n = 336) or rectal stump (n = 51) specimen histopathology reports.

Table 1.

Baseline characteristics (N = 481).

All patients (N = 481)CDP (n = 47)No CDP (n = 434)P valueMissing
Postoperative follow-up, y6.2 (2.3-13.5)22.9 (12.1-27.4)5.4 (2.0-11.9)<.01a0 (0)
Female236 (49)19 (40)217 (50).2120 (0)
Diagnosis before colectomy.7980 (0)
 UC468 (97)46 (98)422 (97)
 IBD-U13 (3)1 (2)12 (27)
Age at diagnosis, y28.7 (20.6-37.6)24.6 (18.8-32.3)29.5 (20.7-38.0).036a60 (12)
Disease duration at time of colectomy, y4.1 (1.5-8.0)3.3 (1.2-5.8)4.1 (1.5-8.3).12662 (13)
Histology report resection specimenb.05194 (19)
 Fitting UC289 (60)29 (62)260 (60)
 Indeterminate63 (13)5 (11)58 (13)
 Fitting CD35 (7)8 (17)27 (6)
Colectomy setting.96374 (15)
 Elective253 (53)25 (53)228 (53)
 (Semi)urgent154 (32)15 (32)139 (32)
Age at time of IPAA y35.9 (27.9-44.7)30.3 (23.3-38.4)36.7 (28.4-45.4)<.01a0 (0)
Stages IPAA surgery.7373 (1)
 1140 (29)15 (32)125 (29)
 280 (17)10 (21)70 (16)
 Modified 2213 (44)18 (38)195 (45)
 345 (9)4 (9)41 (9)
Smoking.345149 (31)
 No260 (54)14 (30)246 (57)
 Previously25 (5)3 (6)22 (5)
 Yes47 (10)4 (9)43 (10)
Pouch excision during follow-up18 (4)6 (13)12 (3)<.01a0 (0)
All patients (N = 481)CDP (n = 47)No CDP (n = 434)P valueMissing
Postoperative follow-up, y6.2 (2.3-13.5)22.9 (12.1-27.4)5.4 (2.0-11.9)<.01a0 (0)
Female236 (49)19 (40)217 (50).2120 (0)
Diagnosis before colectomy.7980 (0)
 UC468 (97)46 (98)422 (97)
 IBD-U13 (3)1 (2)12 (27)
Age at diagnosis, y28.7 (20.6-37.6)24.6 (18.8-32.3)29.5 (20.7-38.0).036a60 (12)
Disease duration at time of colectomy, y4.1 (1.5-8.0)3.3 (1.2-5.8)4.1 (1.5-8.3).12662 (13)
Histology report resection specimenb.05194 (19)
 Fitting UC289 (60)29 (62)260 (60)
 Indeterminate63 (13)5 (11)58 (13)
 Fitting CD35 (7)8 (17)27 (6)
Colectomy setting.96374 (15)
 Elective253 (53)25 (53)228 (53)
 (Semi)urgent154 (32)15 (32)139 (32)
Age at time of IPAA y35.9 (27.9-44.7)30.3 (23.3-38.4)36.7 (28.4-45.4)<.01a0 (0)
Stages IPAA surgery.7373 (1)
 1140 (29)15 (32)125 (29)
 280 (17)10 (21)70 (16)
 Modified 2213 (44)18 (38)195 (45)
 345 (9)4 (9)41 (9)
Smoking.345149 (31)
 No260 (54)14 (30)246 (57)
 Previously25 (5)3 (6)22 (5)
 Yes47 (10)4 (9)43 (10)
Pouch excision during follow-up18 (4)6 (13)12 (3)<.01a0 (0)

Values are median (interquartile range) or n (%).

Abbreviations: CD, Crohn’s disease; CDP, Crohn’s disease of the pouch; IBD-U, inflammatory bowel disease unclassified; IPAA, ileal pouch–anal anastomosis; UC, ulcerative colitis.

aDenotes that P value reaches statistical significance.

bDerived from colonic (n = 336) or rectal stump (n = 51) specimen histopathology reports.

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