Table 2.
Open in new tab

Association Between ES-SCZ and the 5-Factor Model of Personality by Group

Biotype 1Biotype 2Biotype 3ControlsSchizophreniaSchizoaffectiveBipolar w psychosis
Openness0.141 [0.028, 0.254]0.074 [−0.059, 0.206]0.071 [−0.037, 0.181]0.092 [0.002, 0.187]0.077 [−0.04, 0.174]0.018 [−0.092, 0.126]0.169 [0.041, 0.298]*
Conscientiousness−0.141 [−0.299, −0.048]−0.101 [−0.238, −0.036]−0.107 [−0.247, −0.003]−0.272 [−0.366, −0.179]*−0.083 [−0.247, −0.014]−0.163 [−0.278, −0.048]*−0.045 [−0.189, 0.111]
Extraversion−0.073 [−0.216, 0.04]−0.050 [−0.216, 0.04]−0.015 [−0.149, 0.095]−0.149 [−0.246, −0.052]*−0.038 [−0.167, 0.062]−0.044 [−0.163, 0.073]−0.040 [−0.195, 0.11]
Agreeableness−0.222 [−0.350, −0.09]*−0.156 [−0.290, −0.02]*−0.12 [−0.241, 0.001]−0.248 [−0.337, −0.159]*−0.149 [−0.271, −0.027]*−0.195 [−0.314, −0.075]*−0.152 [−0.292, 0.006]
Neuroticism0.160 [0.033, 0.287]*0.138 [0.00, 0.277]0.149 [0.025, 0.273]*0.263 [0.169, 0.357]*0.124 [0.001, 0.248]0.170 [0.050, 0.290]*0.118 [−0.043, 0.264]
Biotype 1Biotype 2Biotype 3ControlsSchizophreniaSchizoaffectiveBipolar w psychosis
Openness0.141 [0.028, 0.254]0.074 [−0.059, 0.206]0.071 [−0.037, 0.181]0.092 [0.002, 0.187]0.077 [−0.04, 0.174]0.018 [−0.092, 0.126]0.169 [0.041, 0.298]*
Conscientiousness−0.141 [−0.299, −0.048]−0.101 [−0.238, −0.036]−0.107 [−0.247, −0.003]−0.272 [−0.366, −0.179]*−0.083 [−0.247, −0.014]−0.163 [−0.278, −0.048]*−0.045 [−0.189, 0.111]
Extraversion−0.073 [−0.216, 0.04]−0.050 [−0.216, 0.04]−0.015 [−0.149, 0.095]−0.149 [−0.246, −0.052]*−0.038 [−0.167, 0.062]−0.044 [−0.163, 0.073]−0.040 [−0.195, 0.11]
Agreeableness−0.222 [−0.350, −0.09]*−0.156 [−0.290, −0.02]*−0.12 [−0.241, 0.001]−0.248 [−0.337, −0.159]*−0.149 [−0.271, −0.027]*−0.195 [−0.314, −0.075]*−0.152 [−0.292, 0.006]
Neuroticism0.160 [0.033, 0.287]*0.138 [0.00, 0.277]0.149 [0.025, 0.273]*0.263 [0.169, 0.357]*0.124 [0.001, 0.248]0.170 [0.050, 0.290]*0.118 [−0.043, 0.264]

*p < 0.05 after correction for multiple comparisons.

Table 2.
Open in new tab

Association Between ES-SCZ and the 5-Factor Model of Personality by Group

Biotype 1Biotype 2Biotype 3ControlsSchizophreniaSchizoaffectiveBipolar w psychosis
Openness0.141 [0.028, 0.254]0.074 [−0.059, 0.206]0.071 [−0.037, 0.181]0.092 [0.002, 0.187]0.077 [−0.04, 0.174]0.018 [−0.092, 0.126]0.169 [0.041, 0.298]*
Conscientiousness−0.141 [−0.299, −0.048]−0.101 [−0.238, −0.036]−0.107 [−0.247, −0.003]−0.272 [−0.366, −0.179]*−0.083 [−0.247, −0.014]−0.163 [−0.278, −0.048]*−0.045 [−0.189, 0.111]
Extraversion−0.073 [−0.216, 0.04]−0.050 [−0.216, 0.04]−0.015 [−0.149, 0.095]−0.149 [−0.246, −0.052]*−0.038 [−0.167, 0.062]−0.044 [−0.163, 0.073]−0.040 [−0.195, 0.11]
Agreeableness−0.222 [−0.350, −0.09]*−0.156 [−0.290, −0.02]*−0.12 [−0.241, 0.001]−0.248 [−0.337, −0.159]*−0.149 [−0.271, −0.027]*−0.195 [−0.314, −0.075]*−0.152 [−0.292, 0.006]
Neuroticism0.160 [0.033, 0.287]*0.138 [0.00, 0.277]0.149 [0.025, 0.273]*0.263 [0.169, 0.357]*0.124 [0.001, 0.248]0.170 [0.050, 0.290]*0.118 [−0.043, 0.264]
Biotype 1Biotype 2Biotype 3ControlsSchizophreniaSchizoaffectiveBipolar w psychosis
Openness0.141 [0.028, 0.254]0.074 [−0.059, 0.206]0.071 [−0.037, 0.181]0.092 [0.002, 0.187]0.077 [−0.04, 0.174]0.018 [−0.092, 0.126]0.169 [0.041, 0.298]*
Conscientiousness−0.141 [−0.299, −0.048]−0.101 [−0.238, −0.036]−0.107 [−0.247, −0.003]−0.272 [−0.366, −0.179]*−0.083 [−0.247, −0.014]−0.163 [−0.278, −0.048]*−0.045 [−0.189, 0.111]
Extraversion−0.073 [−0.216, 0.04]−0.050 [−0.216, 0.04]−0.015 [−0.149, 0.095]−0.149 [−0.246, −0.052]*−0.038 [−0.167, 0.062]−0.044 [−0.163, 0.073]−0.040 [−0.195, 0.11]
Agreeableness−0.222 [−0.350, −0.09]*−0.156 [−0.290, −0.02]*−0.12 [−0.241, 0.001]−0.248 [−0.337, −0.159]*−0.149 [−0.271, −0.027]*−0.195 [−0.314, −0.075]*−0.152 [−0.292, 0.006]
Neuroticism0.160 [0.033, 0.287]*0.138 [0.00, 0.277]0.149 [0.025, 0.273]*0.263 [0.169, 0.357]*0.124 [0.001, 0.248]0.170 [0.050, 0.290]*0.118 [−0.043, 0.264]

*p < 0.05 after correction for multiple comparisons.

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