Table 2

Maternal outcomes at 6 months, stratified by bromocriptine treatment

 No bromocriptine
(n = 467)
Bromocriptine
(n = 85)
P-valuen
NYHA functional class at 6 months.830552
 I265 (60.6)50 (63.3)516
 II153 (35.0)27 (34.2)
 III16 (3.7)2 (2.5)
 IV3 (0.7)0 (0.0)
Systolic BP (mmHg) at 6 months110.0 (100.0–120.0)110.0 (104.0–120.0).700
Diastolic BP (mmHg) at 6 months70.0 (65.0–80.0)73.0 (70.0–80.0).062503
Heart rate (b.p.m.) at 6 months76.0 (65.0–84.0)78.0 (70.0–84.0).180503
LVEDD (mm) at 6 months54.0 (48.0–60.0)55.0 (50.0–58.5).660504
LVESD (mm) at 6 months41.5 (35.0–50.0)40.0 (33.0–46.0).140435
LVEF (%) at 6 months48.0 (36.0–56.0)47.0 (42.0–55.5).570381
LVEF categories at 6 months.031467
 ≤35%95 (24.5)12 (15.0)
 36%–49%111 (28.7)34 (42.5)
 ≥50%181 (46.8)34 (42.5)
Any thromboembolism26 (5.6)5 (6.0).900547
Venous thromboembolism18 (3.9)3 (3.6).890547
Arterial thromboembolism10 (2.2)2 (2.4).910548
Ischaemic stroke5 (1.1)2 (2.4).340549
Haemorrhagic stroke2 (0.4)0 (0.0).540550
Any stroke7 (1.5)2 (2.4).570549
Death within 6 months12 (2.6)2 (2.4).910552
Readmission within 6 months49 (10.5)8 (9.4).750550
Severe LV dysfunction at 6 months95 (24.6)12 (15.0).064467
Severe LV dysfunction or death at 6 months107 (26.8)14 (17.1).064481
Adverse maternal outcome at 6 months136 (33.3)18 (22.0).044491
 No bromocriptine
(n = 467)
Bromocriptine
(n = 85)
P-valuen
NYHA functional class at 6 months.830552
 I265 (60.6)50 (63.3)516
 II153 (35.0)27 (34.2)
 III16 (3.7)2 (2.5)
 IV3 (0.7)0 (0.0)
Systolic BP (mmHg) at 6 months110.0 (100.0–120.0)110.0 (104.0–120.0).700
Diastolic BP (mmHg) at 6 months70.0 (65.0–80.0)73.0 (70.0–80.0).062503
Heart rate (b.p.m.) at 6 months76.0 (65.0–84.0)78.0 (70.0–84.0).180503
LVEDD (mm) at 6 months54.0 (48.0–60.0)55.0 (50.0–58.5).660504
LVESD (mm) at 6 months41.5 (35.0–50.0)40.0 (33.0–46.0).140435
LVEF (%) at 6 months48.0 (36.0–56.0)47.0 (42.0–55.5).570381
LVEF categories at 6 months.031467
 ≤35%95 (24.5)12 (15.0)
 36%–49%111 (28.7)34 (42.5)
 ≥50%181 (46.8)34 (42.5)
Any thromboembolism26 (5.6)5 (6.0).900547
Venous thromboembolism18 (3.9)3 (3.6).890547
Arterial thromboembolism10 (2.2)2 (2.4).910548
Ischaemic stroke5 (1.1)2 (2.4).340549
Haemorrhagic stroke2 (0.4)0 (0.0).540550
Any stroke7 (1.5)2 (2.4).570549
Death within 6 months12 (2.6)2 (2.4).910552
Readmission within 6 months49 (10.5)8 (9.4).750550
Severe LV dysfunction at 6 months95 (24.6)12 (15.0).064467
Severe LV dysfunction or death at 6 months107 (26.8)14 (17.1).064481
Adverse maternal outcome at 6 months136 (33.3)18 (22.0).044491

BP, blood pressure; LVH, left ventricular hypertrophy; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association.

Table 2

Maternal outcomes at 6 months, stratified by bromocriptine treatment

 No bromocriptine
(n = 467)
Bromocriptine
(n = 85)
P-valuen
NYHA functional class at 6 months.830552
 I265 (60.6)50 (63.3)516
 II153 (35.0)27 (34.2)
 III16 (3.7)2 (2.5)
 IV3 (0.7)0 (0.0)
Systolic BP (mmHg) at 6 months110.0 (100.0–120.0)110.0 (104.0–120.0).700
Diastolic BP (mmHg) at 6 months70.0 (65.0–80.0)73.0 (70.0–80.0).062503
Heart rate (b.p.m.) at 6 months76.0 (65.0–84.0)78.0 (70.0–84.0).180503
LVEDD (mm) at 6 months54.0 (48.0–60.0)55.0 (50.0–58.5).660504
LVESD (mm) at 6 months41.5 (35.0–50.0)40.0 (33.0–46.0).140435
LVEF (%) at 6 months48.0 (36.0–56.0)47.0 (42.0–55.5).570381
LVEF categories at 6 months.031467
 ≤35%95 (24.5)12 (15.0)
 36%–49%111 (28.7)34 (42.5)
 ≥50%181 (46.8)34 (42.5)
Any thromboembolism26 (5.6)5 (6.0).900547
Venous thromboembolism18 (3.9)3 (3.6).890547
Arterial thromboembolism10 (2.2)2 (2.4).910548
Ischaemic stroke5 (1.1)2 (2.4).340549
Haemorrhagic stroke2 (0.4)0 (0.0).540550
Any stroke7 (1.5)2 (2.4).570549
Death within 6 months12 (2.6)2 (2.4).910552
Readmission within 6 months49 (10.5)8 (9.4).750550
Severe LV dysfunction at 6 months95 (24.6)12 (15.0).064467
Severe LV dysfunction or death at 6 months107 (26.8)14 (17.1).064481
Adverse maternal outcome at 6 months136 (33.3)18 (22.0).044491
 No bromocriptine
(n = 467)
Bromocriptine
(n = 85)
P-valuen
NYHA functional class at 6 months.830552
 I265 (60.6)50 (63.3)516
 II153 (35.0)27 (34.2)
 III16 (3.7)2 (2.5)
 IV3 (0.7)0 (0.0)
Systolic BP (mmHg) at 6 months110.0 (100.0–120.0)110.0 (104.0–120.0).700
Diastolic BP (mmHg) at 6 months70.0 (65.0–80.0)73.0 (70.0–80.0).062503
Heart rate (b.p.m.) at 6 months76.0 (65.0–84.0)78.0 (70.0–84.0).180503
LVEDD (mm) at 6 months54.0 (48.0–60.0)55.0 (50.0–58.5).660504
LVESD (mm) at 6 months41.5 (35.0–50.0)40.0 (33.0–46.0).140435
LVEF (%) at 6 months48.0 (36.0–56.0)47.0 (42.0–55.5).570381
LVEF categories at 6 months.031467
 ≤35%95 (24.5)12 (15.0)
 36%–49%111 (28.7)34 (42.5)
 ≥50%181 (46.8)34 (42.5)
Any thromboembolism26 (5.6)5 (6.0).900547
Venous thromboembolism18 (3.9)3 (3.6).890547
Arterial thromboembolism10 (2.2)2 (2.4).910548
Ischaemic stroke5 (1.1)2 (2.4).340549
Haemorrhagic stroke2 (0.4)0 (0.0).540550
Any stroke7 (1.5)2 (2.4).570549
Death within 6 months12 (2.6)2 (2.4).910552
Readmission within 6 months49 (10.5)8 (9.4).750550
Severe LV dysfunction at 6 months95 (24.6)12 (15.0).064467
Severe LV dysfunction or death at 6 months107 (26.8)14 (17.1).064481
Adverse maternal outcome at 6 months136 (33.3)18 (22.0).044491

BP, blood pressure; LVH, left ventricular hypertrophy; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association.

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