Table 3

Dose-response regression values and statistical testing results for 31 meV thermal neutrons for the DCA and the micronucleus assay.

Dicentric chromosome assay
RadiationRegression(A = c + αD + βD2)α  
[±SE] (Gy−1)
β  
[±SE] (Gy−2)
c  
[±SE]
χ2-test
sig.
α z-test sig.β z-test sig.Pearson’s R2 value
31 meV neutronLinearA = 0.0008 + 0.467D0.467 ± 0.0150.0008 ± 0.00120.668< 0.0011.0
Linear-quadraticA = 0.0009 + 0.387D + 0.259D20.387 ± 0.0420.259 ± 0.1310.0009 ± 0.00060.8650.0030.141.0
Micronucleus assay
RadiationRegression(A = c + αD + βD2)α  
[±SE] (Gy−1)
β  
[±SE] (Gy−2)
c  
[±SE]
χ2-test
sig.
α z-test sig.β z-test sig.Pearson’s R2 value
31 meV neutronLinearA = 0.014 + 0.298D0.298 ± 0.0430.014 ± 0.0110.0020.96
Linear-quadraticA = 0.018 + 0.111D -0.555D20.111 ± 0.1230.555 ± 0.3610.018 ± 0.0060.4350.2220.98
Dicentric chromosome assay
RadiationRegression(A = c + αD + βD2)α  
[±SE] (Gy−1)
β  
[±SE] (Gy−2)
c  
[±SE]
χ2-test
sig.
α z-test sig.β z-test sig.Pearson’s R2 value
31 meV neutronLinearA = 0.0008 + 0.467D0.467 ± 0.0150.0008 ± 0.00120.668< 0.0011.0
Linear-quadraticA = 0.0009 + 0.387D + 0.259D20.387 ± 0.0420.259 ± 0.1310.0009 ± 0.00060.8650.0030.141.0
Micronucleus assay
RadiationRegression(A = c + αD + βD2)α  
[±SE] (Gy−1)
β  
[±SE] (Gy−2)
c  
[±SE]
χ2-test
sig.
α z-test sig.β z-test sig.Pearson’s R2 value
31 meV neutronLinearA = 0.014 + 0.298D0.298 ± 0.0430.014 ± 0.0110.0020.96
Linear-quadraticA = 0.018 + 0.111D -0.555D20.111 ± 0.1230.555 ± 0.3610.018 ± 0.0060.4350.2220.98

A, aberrations per cell; α, β, c, regression coefficients; D, dose (Gy); R2, coefficient of determination; Sig., significance.

Table 3

Dose-response regression values and statistical testing results for 31 meV thermal neutrons for the DCA and the micronucleus assay.

Dicentric chromosome assay
RadiationRegression(A = c + αD + βD2)α  
[±SE] (Gy−1)
β  
[±SE] (Gy−2)
c  
[±SE]
χ2-test
sig.
α z-test sig.β z-test sig.Pearson’s R2 value
31 meV neutronLinearA = 0.0008 + 0.467D0.467 ± 0.0150.0008 ± 0.00120.668< 0.0011.0
Linear-quadraticA = 0.0009 + 0.387D + 0.259D20.387 ± 0.0420.259 ± 0.1310.0009 ± 0.00060.8650.0030.141.0
Micronucleus assay
RadiationRegression(A = c + αD + βD2)α  
[±SE] (Gy−1)
β  
[±SE] (Gy−2)
c  
[±SE]
χ2-test
sig.
α z-test sig.β z-test sig.Pearson’s R2 value
31 meV neutronLinearA = 0.014 + 0.298D0.298 ± 0.0430.014 ± 0.0110.0020.96
Linear-quadraticA = 0.018 + 0.111D -0.555D20.111 ± 0.1230.555 ± 0.3610.018 ± 0.0060.4350.2220.98
Dicentric chromosome assay
RadiationRegression(A = c + αD + βD2)α  
[±SE] (Gy−1)
β  
[±SE] (Gy−2)
c  
[±SE]
χ2-test
sig.
α z-test sig.β z-test sig.Pearson’s R2 value
31 meV neutronLinearA = 0.0008 + 0.467D0.467 ± 0.0150.0008 ± 0.00120.668< 0.0011.0
Linear-quadraticA = 0.0009 + 0.387D + 0.259D20.387 ± 0.0420.259 ± 0.1310.0009 ± 0.00060.8650.0030.141.0
Micronucleus assay
RadiationRegression(A = c + αD + βD2)α  
[±SE] (Gy−1)
β  
[±SE] (Gy−2)
c  
[±SE]
χ2-test
sig.
α z-test sig.β z-test sig.Pearson’s R2 value
31 meV neutronLinearA = 0.014 + 0.298D0.298 ± 0.0430.014 ± 0.0110.0020.96
Linear-quadraticA = 0.018 + 0.111D -0.555D20.111 ± 0.1230.555 ± 0.3610.018 ± 0.0060.4350.2220.98

A, aberrations per cell; α, β, c, regression coefficients; D, dose (Gy); R2, coefficient of determination; Sig., significance.

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