Section/topic#Checklist itemReported on page #
Title
Title1Identifies the report as a systematic review, meta-analysis, or both1
Abstract
Structured summary2Provides a structured summary including, as applicable: background, objectives, data sources, study eligibility criteria, methods, results, limitations, conclusions, and implications of key findings1
Introduction
Rationale3Describes the rationale for the review in the context of existing knowledge2
Objectives4Provide an explicit statement of questions and objectives being addressed with reference to outcomes and study design2–3
Methods
Protocol and registration5Indicate if a review protocol exists, if and where it can be accessed (e.g. Web address), and, if available, provide registration information including registration numberNA
Eligibility criteria6Specify study characteristics (e.g. the presence of theoretical framework) and report characteristics (e.g. years considered, language, and publication status) used as criteria for eligibility, giving rationale3–4;  Appendix C– D
Information sources7Describe all information sources (e.g. databases with dates of coverage) in the search and date last searched3
Search strategy8Presents full electronic search strategy for at least one database, including any limits used, such that it could be repeated3–4, 22;
 Appendix B
Study selection9States the process for selecting studies (i.e. screening, eligibility, and included in systematic review)3–4–5;  Appendix C– D
Data collection process10Describes method of data extraction from reports (e.g. piloted forms, independently, and in duplicate) and any processes for obtaining and confirming data from investigators3–4–5;
 Appendix D
Data items11List and define all variables for which data were sought and any assumptions and simplifications made3–4–5,  Appendix D
Risk of bias in individual studies12Describes methods used for assessing risk of bias of individual studiesNA
Summary measures13State the principal summary measures (e.g. risk ratio and difference in means)6
Synthesis of results14Describes the methods of handling data and combining results of studies5–6
Results
Study selection15Describes the results of the search and selection process, from the numbers of records identified in the search to the number of studies included6–16
Study characteristics16Present the characteristics of studies includedNA
Discussion
Discussion17Provides a general interpretation of the results16–21
Implications18Discuss implications of the results for practice, policy, and future research21–22
Other information
Protocol19Indicates where the review protocol can be accessed Appendix B
Section/topic#Checklist itemReported on page #
Title
Title1Identifies the report as a systematic review, meta-analysis, or both1
Abstract
Structured summary2Provides a structured summary including, as applicable: background, objectives, data sources, study eligibility criteria, methods, results, limitations, conclusions, and implications of key findings1
Introduction
Rationale3Describes the rationale for the review in the context of existing knowledge2
Objectives4Provide an explicit statement of questions and objectives being addressed with reference to outcomes and study design2–3
Methods
Protocol and registration5Indicate if a review protocol exists, if and where it can be accessed (e.g. Web address), and, if available, provide registration information including registration numberNA
Eligibility criteria6Specify study characteristics (e.g. the presence of theoretical framework) and report characteristics (e.g. years considered, language, and publication status) used as criteria for eligibility, giving rationale3–4;  Appendix C– D
Information sources7Describe all information sources (e.g. databases with dates of coverage) in the search and date last searched3
Search strategy8Presents full electronic search strategy for at least one database, including any limits used, such that it could be repeated3–4, 22;
 Appendix B
Study selection9States the process for selecting studies (i.e. screening, eligibility, and included in systematic review)3–4–5;  Appendix C– D
Data collection process10Describes method of data extraction from reports (e.g. piloted forms, independently, and in duplicate) and any processes for obtaining and confirming data from investigators3–4–5;
 Appendix D
Data items11List and define all variables for which data were sought and any assumptions and simplifications made3–4–5,  Appendix D
Risk of bias in individual studies12Describes methods used for assessing risk of bias of individual studiesNA
Summary measures13State the principal summary measures (e.g. risk ratio and difference in means)6
Synthesis of results14Describes the methods of handling data and combining results of studies5–6
Results
Study selection15Describes the results of the search and selection process, from the numbers of records identified in the search to the number of studies included6–16
Study characteristics16Present the characteristics of studies includedNA
Discussion
Discussion17Provides a general interpretation of the results16–21
Implications18Discuss implications of the results for practice, policy, and future research21–22
Other information
Protocol19Indicates where the review protocol can be accessed Appendix B
Section/topic#Checklist itemReported on page #
Title
Title1Identifies the report as a systematic review, meta-analysis, or both1
Abstract
Structured summary2Provides a structured summary including, as applicable: background, objectives, data sources, study eligibility criteria, methods, results, limitations, conclusions, and implications of key findings1
Introduction
Rationale3Describes the rationale for the review in the context of existing knowledge2
Objectives4Provide an explicit statement of questions and objectives being addressed with reference to outcomes and study design2–3
Methods
Protocol and registration5Indicate if a review protocol exists, if and where it can be accessed (e.g. Web address), and, if available, provide registration information including registration numberNA
Eligibility criteria6Specify study characteristics (e.g. the presence of theoretical framework) and report characteristics (e.g. years considered, language, and publication status) used as criteria for eligibility, giving rationale3–4;  Appendix C– D
Information sources7Describe all information sources (e.g. databases with dates of coverage) in the search and date last searched3
Search strategy8Presents full electronic search strategy for at least one database, including any limits used, such that it could be repeated3–4, 22;
 Appendix B
Study selection9States the process for selecting studies (i.e. screening, eligibility, and included in systematic review)3–4–5;  Appendix C– D
Data collection process10Describes method of data extraction from reports (e.g. piloted forms, independently, and in duplicate) and any processes for obtaining and confirming data from investigators3–4–5;
 Appendix D
Data items11List and define all variables for which data were sought and any assumptions and simplifications made3–4–5,  Appendix D
Risk of bias in individual studies12Describes methods used for assessing risk of bias of individual studiesNA
Summary measures13State the principal summary measures (e.g. risk ratio and difference in means)6
Synthesis of results14Describes the methods of handling data and combining results of studies5–6
Results
Study selection15Describes the results of the search and selection process, from the numbers of records identified in the search to the number of studies included6–16
Study characteristics16Present the characteristics of studies includedNA
Discussion
Discussion17Provides a general interpretation of the results16–21
Implications18Discuss implications of the results for practice, policy, and future research21–22
Other information
Protocol19Indicates where the review protocol can be accessed Appendix B
Section/topic#Checklist itemReported on page #
Title
Title1Identifies the report as a systematic review, meta-analysis, or both1
Abstract
Structured summary2Provides a structured summary including, as applicable: background, objectives, data sources, study eligibility criteria, methods, results, limitations, conclusions, and implications of key findings1
Introduction
Rationale3Describes the rationale for the review in the context of existing knowledge2
Objectives4Provide an explicit statement of questions and objectives being addressed with reference to outcomes and study design2–3
Methods
Protocol and registration5Indicate if a review protocol exists, if and where it can be accessed (e.g. Web address), and, if available, provide registration information including registration numberNA
Eligibility criteria6Specify study characteristics (e.g. the presence of theoretical framework) and report characteristics (e.g. years considered, language, and publication status) used as criteria for eligibility, giving rationale3–4;  Appendix C– D
Information sources7Describe all information sources (e.g. databases with dates of coverage) in the search and date last searched3
Search strategy8Presents full electronic search strategy for at least one database, including any limits used, such that it could be repeated3–4, 22;
 Appendix B
Study selection9States the process for selecting studies (i.e. screening, eligibility, and included in systematic review)3–4–5;  Appendix C– D
Data collection process10Describes method of data extraction from reports (e.g. piloted forms, independently, and in duplicate) and any processes for obtaining and confirming data from investigators3–4–5;
 Appendix D
Data items11List and define all variables for which data were sought and any assumptions and simplifications made3–4–5,  Appendix D
Risk of bias in individual studies12Describes methods used for assessing risk of bias of individual studiesNA
Summary measures13State the principal summary measures (e.g. risk ratio and difference in means)6
Synthesis of results14Describes the methods of handling data and combining results of studies5–6
Results
Study selection15Describes the results of the search and selection process, from the numbers of records identified in the search to the number of studies included6–16
Study characteristics16Present the characteristics of studies includedNA
Discussion
Discussion17Provides a general interpretation of the results16–21
Implications18Discuss implications of the results for practice, policy, and future research21–22
Other information
Protocol19Indicates where the review protocol can be accessed Appendix B
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