Table 2. Open in new tab (a) Logistic...

(a)
% likely or very likely	51		64		38

(a)

Type

Clinical drug trial

Clinical drug trial with biospecimen collection research

Clinical drug trial research including colonoscopy

% likely or very likely

(a)
% likely or very likely	51		64		38

Predictors

OR (95% CI)

Age

1.01 (0.99-1.02)

.30

1.01 (0.99-1.03)

.31

1.00 (0.98-1.02)

.92

IBD

Other

0.95 (0.59-1.55)

.84

0.83 (0.49-1.4)

.48

0.85 (0.52-1.40)

.52

1.00 (0.75-1.34)

.99

0.78 (0.57-1.06)

.11

1.21 (0.90-1.63)

.21

ref

Education

1.00 (0.89-1.14)

.95

1.04 (0.91-1.18)

.61

1.06 (0.94-1.21)

.34

Income

0.98 (0.91-1.07)

.71

1.09 (0.99-1.19)

.068

0.99 (0.91-1.08)

.88

Awareness

Very

ref

Somewhat

0.72 (0.51-1.03)

.072

0.77 (0.52-1.13)

.19

0.69 (0.49-0.98)

.037

None

0.51 (0.33-0.77)

.0015

0.46 (0.3-0.72)

.0007

0.54 (0.35-0.82)

.0044

Previous trials (Y vs N)

1.65 (1.21-2.26)

.0018

1.58 (1.12-2.22)

.0097

1.32 (0.97-1.8)

.081

Reason

Access to experts

0.88 (0.43-1.81)

.72

0.62 (0.3-1.3)

.2066

0.47 (0.2-1.09)

.077

Doctor recommendation

0.51 (0.24-1.06)

.069

0.34 (0.16-0.7)

.0037

0.59 (0.27-1.28)

.18

Improve my life

1.21 (0.86-1.70)

.28

1 (0.7-1.45)

.99

1.01 (0.72-1.43)

.96

Newest therapies

1.14 (0.6-2.17)

.68

0.57 (0.29-1.1)

.0909

1.11 (0.59-2.1)

.75

New-to-me therapies

1.11 (0.53-2.33)

.79

1.11 (0.49-2.51)

.81

1.43 (0.69-2.96)

.33

More tests

1.00 (0.42-2.41)

1.00

1.72 (0.6-4.96)

.31

1.53 (0.63-3.71)

.35

Other

0.39 (0.20-0.76)

.0056

0.51 (0.26-0.97)

.042

0.65 (0.33-1.27)

.21

Increase knowledge

ref

Male

1.22 (0.91-1.62)

.18

0.81 (0.60-1.10)

.18

1.28 (0.96-1.71)

.10

Receiving results

Eventually

0.86 (0.62-1.19)

.37

0.68 (0.48-0.96)

.029

0.69 (0.5-0.96)

.027

within 6 months

0.67 (0.4-1.15)

.15

0.47 (0.27-0.82)

.0077

0.74 (0.43-1.28)

.27

within 1 year

0.8 (0.53-1.22)

.31

0.61 (0.39-0.94)

.026

0.6 (0.39-0.93)

.022

don’t care

ref

Comorbidities (Y vs N)

0.99 (0.73-1.34)

.95

0.86 (0.62-1.19)

.37

0.99 (0.73-1.35)

.97

Depression/anxiety (Y vs N)

0.92 (0.67-1.27)

.61

1.28 (0.9-1.81)

.17

1.07 (0.77-1.48)

.69

Employment

Other vs full-time

0.81 (0.54-1.22)

.32

1.13 (0.73-1.75)

.58

1.46 (0.97-2.19)

.072

Retired vs full-time

0.9 (0.58-1.38)

.63

1.07 (0.68-1.69)

.77

1.26 (0.81-1.94)

.30

(b)
% likely or very likely	85		71

(b)

Type

Research using health records

Research using records & specimens

% likely or very likely

(b)
% likely or very likely	85		71

Predictors	OR (95% CI)	P	OR (95% CI)	P
Age	1.00 (0.97-1.02)	.68	1.00 (0.98-1.02)	.88
IBD
Other	1.11 (0.50-2.46)	.80	0.89 (0.51-1.54)
UC	0.81 (0.52-1.27)	.37	0.84 (0.61-1.17)	.30
CD	ref		ref
Education	1.05 (0.87-1.27)	.59	1.01 (0.88-1.16)	.87
Income	1.02 (0.90-1.16)	.74	1.02 (0.93-1.12)	.67
Awareness
Very	Ref		ref
Somewhat	0.47 (0.25-0.87)	.017	0.90 (0.60-1.35)	.61
None	0.31 (0.16-0.63)	.0011	0.62 (0.39-0.98)	.041
Previous trials (Y vs N)	0.60 (0.37-0.95)	.030	1.2 (0.84-1.71)	.33
Reason
Access to experts	0.53 (0.22-1.29)	.16	0.98 (0.45-2.12)	.96
Doctor recommendation	0.98 (0.35-2.76)	.96	0.49 (0.24-1)	.051
Improve my life	0.98 (0.57-1.67)	.94	1.13 (0.76-1.66)	.55
Newest therapies	0.76 (0.30-1.89)	.55	1.01 (0.49-2.07)	.98
New-to-me therapies	0.82 (0.26-2.51)	.72	1.10 (0.47-2.56)	.83
More tests	1.16 (0.25-5.34)	.85	1.01 (0.38-2.74)	.98
Other	0.54 (0.23-1.30)	.17	0.80 (0.40-1.60)	.53
Increase knowledge	ref		ref
Male	0.75 (0.49-1.16)	.20	0.84 (0.61-1.16)	.29
Receiving results
eventually	0.70 (0.41-1.18)	.18	0.73 (0.50-1.06)	.094
within 6 months	0.28 (0.15-0.54)	.0002	0.39 (0.23-0.68)	.0009
within 1 year	0.60 (0.32-1.13)	.11	0.57 (0.36-0.90)	.015
don’t care	ref		ref
Comorbidities (Y vs N)	0.93 (0.59-1.47)	.75	0.96 (0.68-1.34)	.79
Depression/anxiety (Y vs N)	0.70 (0.44-1.12)	.14	0.83 (0.58-1.18)	.30
Employment
Other vs full-time	1.62 (0.81-3.26)	.18	1.44 (0.90-2.30)	.13
Retired vs full-time	1.08 (0.56-2.1)	.81	1.17 (0.72-1.88)	.53

Predictors

OR (95% CI)

Age

1.00 (0.97-1.02)

.68

1.00 (0.98-1.02)

.88

IBD

Other

1.11 (0.50-2.46)

.80

0.89 (0.51-1.54)

0.81 (0.52-1.27)

.37

0.84 (0.61-1.17)

.30

ref

Education

1.05 (0.87-1.27)

.59

1.01 (0.88-1.16)

.87

Income

1.02 (0.90-1.16)

.74

1.02 (0.93-1.12)

.67

Awareness

Very

Ref

ref

Somewhat

0.47 (0.25-0.87)

.017

0.90 (0.60-1.35)

.61

None

0.31 (0.16-0.63)

.0011

0.62 (0.39-0.98)

.041

Previous trials (Y vs N)

0.60 (0.37-0.95)

.030

1.2 (0.84-1.71)

.33

Reason

Access to experts

0.53 (0.22-1.29)

.16

0.98 (0.45-2.12)

.96

Doctor recommendation

0.98 (0.35-2.76)

.96

0.49 (0.24-1)

.051

Improve my life

0.98 (0.57-1.67)

.94

1.13 (0.76-1.66)

.55

Newest therapies

0.76 (0.30-1.89)

.55

1.01 (0.49-2.07)

.98

New-to-me therapies

0.82 (0.26-2.51)

.72

1.10 (0.47-2.56)

.83

More tests

1.16 (0.25-5.34)

.85

1.01 (0.38-2.74)

.98

Other

0.54 (0.23-1.30)

.17

0.80 (0.40-1.60)

.53

Increase knowledge

ref

Male

0.75 (0.49-1.16)

.20

0.84 (0.61-1.16)

.29

Receiving results

eventually

0.70 (0.41-1.18)

.18

0.73 (0.50-1.06)

.094

within 6 months

0.28 (0.15-0.54)

.0002

0.39 (0.23-0.68)

.0009

within 1 year

0.60 (0.32-1.13)

.11

0.57 (0.36-0.90)

.015

don’t care

ref

Comorbidities (Y vs N)

0.93 (0.59-1.47)

.75

0.96 (0.68-1.34)

.79

Depression/anxiety (Y vs N)

0.70 (0.44-1.12)

.14

0.83 (0.58-1.18)

.30

Employment

Other vs full-time

1.62 (0.81-3.26)

.18

1.44 (0.90-2.30)

.13

Retired vs full-time

1.08 (0.56-2.1)

.81

1.17 (0.72-1.88)

.53

Predictors	OR (95% CI)	P	OR (95% CI)	P
Age	1.00 (0.97-1.02)	.68	1.00 (0.98-1.02)	.88
IBD
Other	1.11 (0.50-2.46)	.80	0.89 (0.51-1.54)
UC	0.81 (0.52-1.27)	.37	0.84 (0.61-1.17)	.30
CD	ref		ref
Education	1.05 (0.87-1.27)	.59	1.01 (0.88-1.16)	.87
Income	1.02 (0.90-1.16)	.74	1.02 (0.93-1.12)	.67
Awareness
Very	Ref		ref
Somewhat	0.47 (0.25-0.87)	.017	0.90 (0.60-1.35)	.61
None	0.31 (0.16-0.63)	.0011	0.62 (0.39-0.98)	.041
Previous trials (Y vs N)	0.60 (0.37-0.95)	.030	1.2 (0.84-1.71)	.33
Reason
Access to experts	0.53 (0.22-1.29)	.16	0.98 (0.45-2.12)	.96
Doctor recommendation	0.98 (0.35-2.76)	.96	0.49 (0.24-1)	.051
Improve my life	0.98 (0.57-1.67)	.94	1.13 (0.76-1.66)	.55
Newest therapies	0.76 (0.30-1.89)	.55	1.01 (0.49-2.07)	.98
New-to-me therapies	0.82 (0.26-2.51)	.72	1.10 (0.47-2.56)	.83
More tests	1.16 (0.25-5.34)	.85	1.01 (0.38-2.74)	.98
Other	0.54 (0.23-1.30)	.17	0.80 (0.40-1.60)	.53
Increase knowledge	ref		ref
Male	0.75 (0.49-1.16)	.20	0.84 (0.61-1.16)	.29
Receiving results
eventually	0.70 (0.41-1.18)	.18	0.73 (0.50-1.06)	.094
within 6 months	0.28 (0.15-0.54)	.0002	0.39 (0.23-0.68)	.0009
within 1 year	0.60 (0.32-1.13)	.11	0.57 (0.36-0.90)	.015
don’t care	ref		ref
Comorbidities (Y vs N)	0.93 (0.59-1.47)	.75	0.96 (0.68-1.34)	.79
Depression/anxiety (Y vs N)	0.70 (0.44-1.12)	.14	0.83 (0.58-1.18)	.30
Employment
Other vs full-time	1.62 (0.81-3.26)	.18	1.44 (0.90-2.30)	.13
Retired vs full-time	1.08 (0.56-2.1)	.81	1.17 (0.72-1.88)	.53

Table 2.

Open in new tab

(a) Logistic analyses modeling responses of “likely” or “very likely” to participate in clinical trials; (b) logistic analyses modeling responses of “likely” or “very likely” to participate in observational research.

(a)
Type	Clinical drug trial		Clinical drug trial with biospecimen collection research		Clinical drug trial research including colonoscopy
% likely or very likely	51		64		38

(a)
Type	Clinical drug trial		Clinical drug trial with biospecimen collection research		Clinical drug trial research including colonoscopy
% likely or very likely	51		64		38

Predictors	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Age	1.01 (0.99-1.02)	.30	1.01 (0.99-1.03)	.31	1.00 (0.98-1.02)	.92
IBD
Other	0.95 (0.59-1.55)	.84	0.83 (0.49-1.4)	.48	0.85 (0.52-1.40)	.52
UC	1.00 (0.75-1.34)	.99	0.78 (0.57-1.06)	.11	1.21 (0.90-1.63)	.21
CD	ref		ref		ref
Education	1.00 (0.89-1.14)	.95	1.04 (0.91-1.18)	.61	1.06 (0.94-1.21)	.34
Income	0.98 (0.91-1.07)	.71	1.09 (0.99-1.19)	.068	0.99 (0.91-1.08)	.88
Awareness
Very	ref		ref		ref
Somewhat	0.72 (0.51-1.03)	.072	0.77 (0.52-1.13)	.19	0.69 (0.49-0.98)	.037
None	0.51 (0.33-0.77)	.0015	0.46 (0.3-0.72)	.0007	0.54 (0.35-0.82)	.0044
Previous trials (Y vs N)	1.65 (1.21-2.26)	.0018	1.58 (1.12-2.22)	.0097	1.32 (0.97-1.8)	.081
Reason
Access to experts	0.88 (0.43-1.81)	.72	0.62 (0.3-1.3)	.2066	0.47 (0.2-1.09)	.077
Doctor recommendation	0.51 (0.24-1.06)	.069	0.34 (0.16-0.7)	.0037	0.59 (0.27-1.28)	.18
Improve my life	1.21 (0.86-1.70)	.28	1 (0.7-1.45)	.99	1.01 (0.72-1.43)	.96
Newest therapies	1.14 (0.6-2.17)	.68	0.57 (0.29-1.1)	.0909	1.11 (0.59-2.1)	.75
New-to-me therapies	1.11 (0.53-2.33)	.79	1.11 (0.49-2.51)	.81	1.43 (0.69-2.96)	.33
More tests	1.00 (0.42-2.41)	1.00	1.72 (0.6-4.96)	.31	1.53 (0.63-3.71)	.35
Other	0.39 (0.20-0.76)	.0056	0.51 (0.26-0.97)	.042	0.65 (0.33-1.27)	.21
Increase knowledge	ref		ref		ref
Male	1.22 (0.91-1.62)	.18	0.81 (0.60-1.10)	.18	1.28 (0.96-1.71)	.10
Receiving results
Eventually	0.86 (0.62-1.19)	.37	0.68 (0.48-0.96)	.029	0.69 (0.5-0.96)	.027
within 6 months	0.67 (0.4-1.15)	.15	0.47 (0.27-0.82)	.0077	0.74 (0.43-1.28)	.27
within 1 year	0.8 (0.53-1.22)	.31	0.61 (0.39-0.94)	.026	0.6 (0.39-0.93)	.022
don’t care	ref		ref		ref
Comorbidities (Y vs N)	0.99 (0.73-1.34)	.95	0.86 (0.62-1.19)	.37	0.99 (0.73-1.35)	.97
Depression/anxiety (Y vs N)	0.92 (0.67-1.27)	.61	1.28 (0.9-1.81)	.17	1.07 (0.77-1.48)	.69
Employment
Other vs full-time	0.81 (0.54-1.22)	.32	1.13 (0.73-1.75)	.58	1.46 (0.97-2.19)	.072
Retired vs full-time	0.9 (0.58-1.38)	.63	1.07 (0.68-1.69)	.77	1.26 (0.81-1.94)	.30

Predictors	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Age	1.01 (0.99-1.02)	.30	1.01 (0.99-1.03)	.31	1.00 (0.98-1.02)	.92
IBD
Other	0.95 (0.59-1.55)	.84	0.83 (0.49-1.4)	.48	0.85 (0.52-1.40)	.52
UC	1.00 (0.75-1.34)	.99	0.78 (0.57-1.06)	.11	1.21 (0.90-1.63)	.21
CD	ref		ref		ref
Education	1.00 (0.89-1.14)	.95	1.04 (0.91-1.18)	.61	1.06 (0.94-1.21)	.34
Income	0.98 (0.91-1.07)	.71	1.09 (0.99-1.19)	.068	0.99 (0.91-1.08)	.88
Awareness
Very	ref		ref		ref
Somewhat	0.72 (0.51-1.03)	.072	0.77 (0.52-1.13)	.19	0.69 (0.49-0.98)	.037
None	0.51 (0.33-0.77)	.0015	0.46 (0.3-0.72)	.0007	0.54 (0.35-0.82)	.0044
Previous trials (Y vs N)	1.65 (1.21-2.26)	.0018	1.58 (1.12-2.22)	.0097	1.32 (0.97-1.8)	.081
Reason
Access to experts	0.88 (0.43-1.81)	.72	0.62 (0.3-1.3)	.2066	0.47 (0.2-1.09)	.077
Doctor recommendation	0.51 (0.24-1.06)	.069	0.34 (0.16-0.7)	.0037	0.59 (0.27-1.28)	.18
Improve my life	1.21 (0.86-1.70)	.28	1 (0.7-1.45)	.99	1.01 (0.72-1.43)	.96
Newest therapies	1.14 (0.6-2.17)	.68	0.57 (0.29-1.1)	.0909	1.11 (0.59-2.1)	.75
New-to-me therapies	1.11 (0.53-2.33)	.79	1.11 (0.49-2.51)	.81	1.43 (0.69-2.96)	.33
More tests	1.00 (0.42-2.41)	1.00	1.72 (0.6-4.96)	.31	1.53 (0.63-3.71)	.35
Other	0.39 (0.20-0.76)	.0056	0.51 (0.26-0.97)	.042	0.65 (0.33-1.27)	.21
Increase knowledge	ref		ref		ref
Male	1.22 (0.91-1.62)	.18	0.81 (0.60-1.10)	.18	1.28 (0.96-1.71)	.10
Receiving results
Eventually	0.86 (0.62-1.19)	.37	0.68 (0.48-0.96)	.029	0.69 (0.5-0.96)	.027
within 6 months	0.67 (0.4-1.15)	.15	0.47 (0.27-0.82)	.0077	0.74 (0.43-1.28)	.27
within 1 year	0.8 (0.53-1.22)	.31	0.61 (0.39-0.94)	.026	0.6 (0.39-0.93)	.022
don’t care	ref		ref		ref
Comorbidities (Y vs N)	0.99 (0.73-1.34)	.95	0.86 (0.62-1.19)	.37	0.99 (0.73-1.35)	.97
Depression/anxiety (Y vs N)	0.92 (0.67-1.27)	.61	1.28 (0.9-1.81)	.17	1.07 (0.77-1.48)	.69
Employment
Other vs full-time	0.81 (0.54-1.22)	.32	1.13 (0.73-1.75)	.58	1.46 (0.97-2.19)	.072
Retired vs full-time	0.9 (0.58-1.38)	.63	1.07 (0.68-1.69)	.77	1.26 (0.81-1.94)	.30

(b)
Type	Research using health records		Research using records & specimens
% likely or very likely	85		71

(b)
% likely or very likely	85		71

Predictors	OR (95% CI)	P	OR (95% CI)	P
Age	1.00 (0.97-1.02)	.68	1.00 (0.98-1.02)	.88
IBD
Other	1.11 (0.50-2.46)	.80	0.89 (0.51-1.54)
UC	0.81 (0.52-1.27)	.37	0.84 (0.61-1.17)	.30
CD	ref		ref
Education	1.05 (0.87-1.27)	.59	1.01 (0.88-1.16)	.87
Income	1.02 (0.90-1.16)	.74	1.02 (0.93-1.12)	.67
Awareness
Very	Ref		ref
Somewhat	0.47 (0.25-0.87)	.017	0.90 (0.60-1.35)	.61
None	0.31 (0.16-0.63)	.0011	0.62 (0.39-0.98)	.041
Previous trials (Y vs N)	0.60 (0.37-0.95)	.030	1.2 (0.84-1.71)	.33
Reason
Access to experts	0.53 (0.22-1.29)	.16	0.98 (0.45-2.12)	.96
Doctor recommendation	0.98 (0.35-2.76)	.96	0.49 (0.24-1)	.051
Improve my life	0.98 (0.57-1.67)	.94	1.13 (0.76-1.66)	.55
Newest therapies	0.76 (0.30-1.89)	.55	1.01 (0.49-2.07)	.98
New-to-me therapies	0.82 (0.26-2.51)	.72	1.10 (0.47-2.56)	.83
More tests	1.16 (0.25-5.34)	.85	1.01 (0.38-2.74)	.98
Other	0.54 (0.23-1.30)	.17	0.80 (0.40-1.60)	.53
Increase knowledge	ref		ref
Male	0.75 (0.49-1.16)	.20	0.84 (0.61-1.16)	.29
Receiving results
eventually	0.70 (0.41-1.18)	.18	0.73 (0.50-1.06)	.094
within 6 months	0.28 (0.15-0.54)	.0002	0.39 (0.23-0.68)	.0009
within 1 year	0.60 (0.32-1.13)	.11	0.57 (0.36-0.90)	.015
don’t care	ref		ref
Comorbidities (Y vs N)	0.93 (0.59-1.47)	.75	0.96 (0.68-1.34)	.79
Depression/anxiety (Y vs N)	0.70 (0.44-1.12)	.14	0.83 (0.58-1.18)	.30
Employment
Other vs full-time	1.62 (0.81-3.26)	.18	1.44 (0.90-2.30)	.13
Retired vs full-time	1.08 (0.56-2.1)	.81	1.17 (0.72-1.88)	.53

Predictors	OR (95% CI)	P	OR (95% CI)	P
Age	1.00 (0.97-1.02)	.68	1.00 (0.98-1.02)	.88
IBD
Other	1.11 (0.50-2.46)	.80	0.89 (0.51-1.54)
UC	0.81 (0.52-1.27)	.37	0.84 (0.61-1.17)	.30
CD	ref		ref
Education	1.05 (0.87-1.27)	.59	1.01 (0.88-1.16)	.87
Income	1.02 (0.90-1.16)	.74	1.02 (0.93-1.12)	.67
Awareness
Very	Ref		ref
Somewhat	0.47 (0.25-0.87)	.017	0.90 (0.60-1.35)	.61
None	0.31 (0.16-0.63)	.0011	0.62 (0.39-0.98)	.041
Previous trials (Y vs N)	0.60 (0.37-0.95)	.030	1.2 (0.84-1.71)	.33
Reason
Access to experts	0.53 (0.22-1.29)	.16	0.98 (0.45-2.12)	.96
Doctor recommendation	0.98 (0.35-2.76)	.96	0.49 (0.24-1)	.051
Improve my life	0.98 (0.57-1.67)	.94	1.13 (0.76-1.66)	.55
Newest therapies	0.76 (0.30-1.89)	.55	1.01 (0.49-2.07)	.98
New-to-me therapies	0.82 (0.26-2.51)	.72	1.10 (0.47-2.56)	.83
More tests	1.16 (0.25-5.34)	.85	1.01 (0.38-2.74)	.98
Other	0.54 (0.23-1.30)	.17	0.80 (0.40-1.60)	.53
Increase knowledge	ref		ref
Male	0.75 (0.49-1.16)	.20	0.84 (0.61-1.16)	.29
Receiving results
eventually	0.70 (0.41-1.18)	.18	0.73 (0.50-1.06)	.094
within 6 months	0.28 (0.15-0.54)	.0002	0.39 (0.23-0.68)	.0009
within 1 year	0.60 (0.32-1.13)	.11	0.57 (0.36-0.90)	.015
don’t care	ref		ref
Comorbidities (Y vs N)	0.93 (0.59-1.47)	.75	0.96 (0.68-1.34)	.79
Depression/anxiety (Y vs N)	0.70 (0.44-1.12)	.14	0.83 (0.58-1.18)	.30
Employment
Other vs full-time	1.62 (0.81-3.26)	.18	1.44 (0.90-2.30)	.13
Retired vs full-time	1.08 (0.56-2.1)	.81	1.17 (0.72-1.88)	.53

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