Comparison of cardiac catheterization parameters at 5 years after Fontan procedure between groups F and N
| Cardiac catheterization at 5 years post-TCPC . | Group F (FIB-4 2 year >0.17) (n = 33) . | Group N (FIB-4 2 year ≤0.17) (n = 60) . | P-value . |
|---|---|---|---|
| Pulmonary artery pressure (mmHg) | 12 (9–14) | 9 (8–11) | 0.01 |
| Pressure gradient between PA and IVC | 0 (0–0) | 0 (0–0) | 0.43 |
| Systemic ventricular end-diastolic pressure (mmHg) | 7 (6–8) | 7 (5–7) | 0.47 |
| Ejection fraction of single ventricle (%) | 62 (58–64) | 63 (58–69) | 0.02 |
| Pulmonary artery vascular resistance (U/m2) | 1.4 (1.0–1.8) | 1.2 (0.8–1.7) | 0.27 |
| Pulmonary artery index (Nakata index) (mm2/m2) | 196 (143–232) | 217 (184–381) | 0.11 |
| Cardiac index (L/min/m2) | 3.3 (2.9–3.6) | 3.8 (3.2–4.5) | 0.03 |
| AVVR ≥moderate (%) | 6 (18.2) | 6 (10.0) | 0.34 |
| Cardiac catheterization at 5 years post-TCPC . | Group F (FIB-4 2 year >0.17) (n = 33) . | Group N (FIB-4 2 year ≤0.17) (n = 60) . | P-value . |
|---|---|---|---|
| Pulmonary artery pressure (mmHg) | 12 (9–14) | 9 (8–11) | 0.01 |
| Pressure gradient between PA and IVC | 0 (0–0) | 0 (0–0) | 0.43 |
| Systemic ventricular end-diastolic pressure (mmHg) | 7 (6–8) | 7 (5–7) | 0.47 |
| Ejection fraction of single ventricle (%) | 62 (58–64) | 63 (58–69) | 0.02 |
| Pulmonary artery vascular resistance (U/m2) | 1.4 (1.0–1.8) | 1.2 (0.8–1.7) | 0.27 |
| Pulmonary artery index (Nakata index) (mm2/m2) | 196 (143–232) | 217 (184–381) | 0.11 |
| Cardiac index (L/min/m2) | 3.3 (2.9–3.6) | 3.8 (3.2–4.5) | 0.03 |
| AVVR ≥moderate (%) | 6 (18.2) | 6 (10.0) | 0.34 |
Comparison between group F (FIB-4 index >0.17) and group N (FIB-4 index ≤0.17) at 2 years post-TCPC.
Data presented as median (interquartile range).
AVVR: atrioventricular valve regurgitation; FIB-4: Fibrosis-4 index; IVC: inferior vena cava; PA: pulmonary artery; TCPC: total cavopulmonary connection.
Comparison of cardiac catheterization parameters at 5 years after Fontan procedure between groups F and N
| Cardiac catheterization at 5 years post-TCPC . | Group F (FIB-4 2 year >0.17) (n = 33) . | Group N (FIB-4 2 year ≤0.17) (n = 60) . | P-value . |
|---|---|---|---|
| Pulmonary artery pressure (mmHg) | 12 (9–14) | 9 (8–11) | 0.01 |
| Pressure gradient between PA and IVC | 0 (0–0) | 0 (0–0) | 0.43 |
| Systemic ventricular end-diastolic pressure (mmHg) | 7 (6–8) | 7 (5–7) | 0.47 |
| Ejection fraction of single ventricle (%) | 62 (58–64) | 63 (58–69) | 0.02 |
| Pulmonary artery vascular resistance (U/m2) | 1.4 (1.0–1.8) | 1.2 (0.8–1.7) | 0.27 |
| Pulmonary artery index (Nakata index) (mm2/m2) | 196 (143–232) | 217 (184–381) | 0.11 |
| Cardiac index (L/min/m2) | 3.3 (2.9–3.6) | 3.8 (3.2–4.5) | 0.03 |
| AVVR ≥moderate (%) | 6 (18.2) | 6 (10.0) | 0.34 |
| Cardiac catheterization at 5 years post-TCPC . | Group F (FIB-4 2 year >0.17) (n = 33) . | Group N (FIB-4 2 year ≤0.17) (n = 60) . | P-value . |
|---|---|---|---|
| Pulmonary artery pressure (mmHg) | 12 (9–14) | 9 (8–11) | 0.01 |
| Pressure gradient between PA and IVC | 0 (0–0) | 0 (0–0) | 0.43 |
| Systemic ventricular end-diastolic pressure (mmHg) | 7 (6–8) | 7 (5–7) | 0.47 |
| Ejection fraction of single ventricle (%) | 62 (58–64) | 63 (58–69) | 0.02 |
| Pulmonary artery vascular resistance (U/m2) | 1.4 (1.0–1.8) | 1.2 (0.8–1.7) | 0.27 |
| Pulmonary artery index (Nakata index) (mm2/m2) | 196 (143–232) | 217 (184–381) | 0.11 |
| Cardiac index (L/min/m2) | 3.3 (2.9–3.6) | 3.8 (3.2–4.5) | 0.03 |
| AVVR ≥moderate (%) | 6 (18.2) | 6 (10.0) | 0.34 |
Comparison between group F (FIB-4 index >0.17) and group N (FIB-4 index ≤0.17) at 2 years post-TCPC.
Data presented as median (interquartile range).
AVVR: atrioventricular valve regurgitation; FIB-4: Fibrosis-4 index; IVC: inferior vena cava; PA: pulmonary artery; TCPC: total cavopulmonary connection.
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