| . | Total, n = 952 . | SR, n = 751 . | AF, n = 201 . | P . |
|---|---|---|---|---|
| General features | ||||
| Age, median (mean ± SD) | 79 (79.2, 6.2) | 78 (78.7, 6.3) | 81 (81.0, 6.2) | <.001 |
| Female sex, n (%) | 445 (46.7) | 410 (54.6) | 97 (48.3) | .112 |
| Number of prescription drugs, mean (± SD) | 6 (4.2) | 5.8 (4.0) | 8.4 (4.1) | <.001 |
| Systolic bloodpressure, mean (± SD) in mmHg | 151.4 (22.9) | 152.5 (22.4) | 147.3 (24.3) | .006 |
| Diastolic bloodpressure, mean (± SD) in mmHg | 80.4 (11.5) | 81.2 (11.1) | 78.0 (12.3) | .001 |
| Polypharmacy, n (%) | 496 (52.1) | 347 (46.2) | 149 (74.1) | <.001 |
| Hypertension, n (%) | 523 (54.9) | 400 (53.5) | 123 (61.2) | .046 |
| Hypercholesterolemia, n (%) | 187 (19.6) | 148 (19.7) | 39 (19.4) | 1.0 |
| Diabetes mellitus, n (%) | 222 (23.3) | 161 (21.4) | 61 (30.3) | .011 |
| Stroke in medical history, n (%) | 194 (20.4) | 142 (18.9) | 52 (25.9) | .024 |
| Major bleeding in medical history, n (%) | 62 (8.8) | 45 (8.2) | 17 (10.8) | .337 |
| Heart failure, n (%) | 75 (7.9) | 23 (3.1) | 52 (25.9) | <.001 |
| Ischemic heart disease or angina pectoris, n (%) | 196 (20.6) | 139 (18.5) | 57 (28.4) | .003 |
| Peripheral arterial disease, n (%) | 70 (7.4) | 51 (6.8) | 19 (9.5) | .223 |
| Thyroid disease, n (%) | 132 (13.8) | 109 (14.5) | 24 (11.9) | .884 |
| Chronic obstructive pulmonary disease, n (%) | 104 (10.9) | 74 (9.9) | 30 (14.9) | .055 |
| Asthma, n (%) | 53 (5.6) | 39 (5.2) | 14 (7.0) | .385 |
| Obstructive sleep apnoe syndrome, n (%) | 56 (5.9) | 40 (5.3) | 16 (8.0) | .176 |
| Laboratory | ||||
| Hemoglobine level, mean (± SD) in mmol/l | 8.4 (1.0) | 8.5 (1.0) | 8.2 (1.2) | .004 |
| Anaemia, sex adjusted, n (%) | 255 (26.8) | 182 (24.2) | 73 (36.3) | .001 |
| Estimated glomerulal filtration rate, mean (± SD) in ml/min | 69.0 (16.9) | 70.4 (16.1) | 62.5 (19.3) | <.001 |
| Geriatric features | ||||
| FI, mean (± SD) | 0.16 (0.08) | 0.15 (0.08) | 0.19 (0.08) | <.001 |
| Frailty categories | ||||
| Robust, n (%) | 641 (67.3) | 538 (71.6) | 103 (51.2) | <.001 |
| Moderate frailty, n (%) | 175 (18.4) | 127 (16.9) | 48 (23.9) | <.001 |
| Severe frailty, n (%) | 136 (14.3) | 86 (11.5) | 50 (24.9) | <.001 |
| Cognitive function | ||||
| Normal, n (%) | 545 (57.2) | 424 (56.5) | 121 (60.1) | .229 |
| Mild cognitive impairment, n (%) | 272 (28.6) | 213 (28.4) | 59 (29.4) | .229 |
| Dementia, n (%) | 135 (14.2) | 114 (15.2) | 21 (10.4) | .229 |
| MMSE score, mean (± SD) | 26.5 (3.6) | 25.6 (4.1) | 25.9 (3.5) | .417 |
| MoCA score, mean (± SD) | 23.3 (3.8) | 23.7 (4.0) | 23.3 (3.5) | .307 |
| Diminished hand grip strength, n (%) | 152 (16.0) | 118 (15.7) | 35 (17.4) | .523 |
| Gait disorder, n (%) | 399 (41.9) | 299 (39.8) | 100 (49.8) | .013 |
| Walking aid, n (%) | 299 (31.4) | 211 (28.1) | 88 (43.8) | <.001 |
| Falls, n (%) | 394 (41.4) | 314 (41.8) | 80 (39.8) | .629 |
| Parkinsonism, n (%) | 61 (6.4) | 48 (6.4) | 13 (6.5) | 1.0 |
| Dependence in ADL, n (%) | 134 (14.1) | 101 (13.4) | 34 (16.9) | .317 |
| Dependence in iADL, n (%) | 376 (39.5) | 284 (37.8) | 93 (46.3) | .075 |
| Visual impairment, n (%) | 196 (20.6) | 155 (20.6) | 41 (20.4) | 1.0 |
| Hearing impairment, n (%) | 265 (27.8) | 212 (28.2) | 53 (26.4) | .658 |
| . | Total, n = 952 . | SR, n = 751 . | AF, n = 201 . | P . |
|---|---|---|---|---|
| General features | ||||
| Age, median (mean ± SD) | 79 (79.2, 6.2) | 78 (78.7, 6.3) | 81 (81.0, 6.2) | <.001 |
| Female sex, n (%) | 445 (46.7) | 410 (54.6) | 97 (48.3) | .112 |
| Number of prescription drugs, mean (± SD) | 6 (4.2) | 5.8 (4.0) | 8.4 (4.1) | <.001 |
| Systolic bloodpressure, mean (± SD) in mmHg | 151.4 (22.9) | 152.5 (22.4) | 147.3 (24.3) | .006 |
| Diastolic bloodpressure, mean (± SD) in mmHg | 80.4 (11.5) | 81.2 (11.1) | 78.0 (12.3) | .001 |
| Polypharmacy, n (%) | 496 (52.1) | 347 (46.2) | 149 (74.1) | <.001 |
| Hypertension, n (%) | 523 (54.9) | 400 (53.5) | 123 (61.2) | .046 |
| Hypercholesterolemia, n (%) | 187 (19.6) | 148 (19.7) | 39 (19.4) | 1.0 |
| Diabetes mellitus, n (%) | 222 (23.3) | 161 (21.4) | 61 (30.3) | .011 |
| Stroke in medical history, n (%) | 194 (20.4) | 142 (18.9) | 52 (25.9) | .024 |
| Major bleeding in medical history, n (%) | 62 (8.8) | 45 (8.2) | 17 (10.8) | .337 |
| Heart failure, n (%) | 75 (7.9) | 23 (3.1) | 52 (25.9) | <.001 |
| Ischemic heart disease or angina pectoris, n (%) | 196 (20.6) | 139 (18.5) | 57 (28.4) | .003 |
| Peripheral arterial disease, n (%) | 70 (7.4) | 51 (6.8) | 19 (9.5) | .223 |
| Thyroid disease, n (%) | 132 (13.8) | 109 (14.5) | 24 (11.9) | .884 |
| Chronic obstructive pulmonary disease, n (%) | 104 (10.9) | 74 (9.9) | 30 (14.9) | .055 |
| Asthma, n (%) | 53 (5.6) | 39 (5.2) | 14 (7.0) | .385 |
| Obstructive sleep apnoe syndrome, n (%) | 56 (5.9) | 40 (5.3) | 16 (8.0) | .176 |
| Laboratory | ||||
| Hemoglobine level, mean (± SD) in mmol/l | 8.4 (1.0) | 8.5 (1.0) | 8.2 (1.2) | .004 |
| Anaemia, sex adjusted, n (%) | 255 (26.8) | 182 (24.2) | 73 (36.3) | .001 |
| Estimated glomerulal filtration rate, mean (± SD) in ml/min | 69.0 (16.9) | 70.4 (16.1) | 62.5 (19.3) | <.001 |
| Geriatric features | ||||
| FI, mean (± SD) | 0.16 (0.08) | 0.15 (0.08) | 0.19 (0.08) | <.001 |
| Frailty categories | ||||
| Robust, n (%) | 641 (67.3) | 538 (71.6) | 103 (51.2) | <.001 |
| Moderate frailty, n (%) | 175 (18.4) | 127 (16.9) | 48 (23.9) | <.001 |
| Severe frailty, n (%) | 136 (14.3) | 86 (11.5) | 50 (24.9) | <.001 |
| Cognitive function | ||||
| Normal, n (%) | 545 (57.2) | 424 (56.5) | 121 (60.1) | .229 |
| Mild cognitive impairment, n (%) | 272 (28.6) | 213 (28.4) | 59 (29.4) | .229 |
| Dementia, n (%) | 135 (14.2) | 114 (15.2) | 21 (10.4) | .229 |
| MMSE score, mean (± SD) | 26.5 (3.6) | 25.6 (4.1) | 25.9 (3.5) | .417 |
| MoCA score, mean (± SD) | 23.3 (3.8) | 23.7 (4.0) | 23.3 (3.5) | .307 |
| Diminished hand grip strength, n (%) | 152 (16.0) | 118 (15.7) | 35 (17.4) | .523 |
| Gait disorder, n (%) | 399 (41.9) | 299 (39.8) | 100 (49.8) | .013 |
| Walking aid, n (%) | 299 (31.4) | 211 (28.1) | 88 (43.8) | <.001 |
| Falls, n (%) | 394 (41.4) | 314 (41.8) | 80 (39.8) | .629 |
| Parkinsonism, n (%) | 61 (6.4) | 48 (6.4) | 13 (6.5) | 1.0 |
| Dependence in ADL, n (%) | 134 (14.1) | 101 (13.4) | 34 (16.9) | .317 |
| Dependence in iADL, n (%) | 376 (39.5) | 284 (37.8) | 93 (46.3) | .075 |
| Visual impairment, n (%) | 196 (20.6) | 155 (20.6) | 41 (20.4) | 1.0 |
| Hearing impairment, n (%) | 265 (27.8) | 212 (28.2) | 53 (26.4) | .658 |
| . | Total, n = 952 . | SR, n = 751 . | AF, n = 201 . | P . |
|---|---|---|---|---|
| General features | ||||
| Age, median (mean ± SD) | 79 (79.2, 6.2) | 78 (78.7, 6.3) | 81 (81.0, 6.2) | <.001 |
| Female sex, n (%) | 445 (46.7) | 410 (54.6) | 97 (48.3) | .112 |
| Number of prescription drugs, mean (± SD) | 6 (4.2) | 5.8 (4.0) | 8.4 (4.1) | <.001 |
| Systolic bloodpressure, mean (± SD) in mmHg | 151.4 (22.9) | 152.5 (22.4) | 147.3 (24.3) | .006 |
| Diastolic bloodpressure, mean (± SD) in mmHg | 80.4 (11.5) | 81.2 (11.1) | 78.0 (12.3) | .001 |
| Polypharmacy, n (%) | 496 (52.1) | 347 (46.2) | 149 (74.1) | <.001 |
| Hypertension, n (%) | 523 (54.9) | 400 (53.5) | 123 (61.2) | .046 |
| Hypercholesterolemia, n (%) | 187 (19.6) | 148 (19.7) | 39 (19.4) | 1.0 |
| Diabetes mellitus, n (%) | 222 (23.3) | 161 (21.4) | 61 (30.3) | .011 |
| Stroke in medical history, n (%) | 194 (20.4) | 142 (18.9) | 52 (25.9) | .024 |
| Major bleeding in medical history, n (%) | 62 (8.8) | 45 (8.2) | 17 (10.8) | .337 |
| Heart failure, n (%) | 75 (7.9) | 23 (3.1) | 52 (25.9) | <.001 |
| Ischemic heart disease or angina pectoris, n (%) | 196 (20.6) | 139 (18.5) | 57 (28.4) | .003 |
| Peripheral arterial disease, n (%) | 70 (7.4) | 51 (6.8) | 19 (9.5) | .223 |
| Thyroid disease, n (%) | 132 (13.8) | 109 (14.5) | 24 (11.9) | .884 |
| Chronic obstructive pulmonary disease, n (%) | 104 (10.9) | 74 (9.9) | 30 (14.9) | .055 |
| Asthma, n (%) | 53 (5.6) | 39 (5.2) | 14 (7.0) | .385 |
| Obstructive sleep apnoe syndrome, n (%) | 56 (5.9) | 40 (5.3) | 16 (8.0) | .176 |
| Laboratory | ||||
| Hemoglobine level, mean (± SD) in mmol/l | 8.4 (1.0) | 8.5 (1.0) | 8.2 (1.2) | .004 |
| Anaemia, sex adjusted, n (%) | 255 (26.8) | 182 (24.2) | 73 (36.3) | .001 |
| Estimated glomerulal filtration rate, mean (± SD) in ml/min | 69.0 (16.9) | 70.4 (16.1) | 62.5 (19.3) | <.001 |
| Geriatric features | ||||
| FI, mean (± SD) | 0.16 (0.08) | 0.15 (0.08) | 0.19 (0.08) | <.001 |
| Frailty categories | ||||
| Robust, n (%) | 641 (67.3) | 538 (71.6) | 103 (51.2) | <.001 |
| Moderate frailty, n (%) | 175 (18.4) | 127 (16.9) | 48 (23.9) | <.001 |
| Severe frailty, n (%) | 136 (14.3) | 86 (11.5) | 50 (24.9) | <.001 |
| Cognitive function | ||||
| Normal, n (%) | 545 (57.2) | 424 (56.5) | 121 (60.1) | .229 |
| Mild cognitive impairment, n (%) | 272 (28.6) | 213 (28.4) | 59 (29.4) | .229 |
| Dementia, n (%) | 135 (14.2) | 114 (15.2) | 21 (10.4) | .229 |
| MMSE score, mean (± SD) | 26.5 (3.6) | 25.6 (4.1) | 25.9 (3.5) | .417 |
| MoCA score, mean (± SD) | 23.3 (3.8) | 23.7 (4.0) | 23.3 (3.5) | .307 |
| Diminished hand grip strength, n (%) | 152 (16.0) | 118 (15.7) | 35 (17.4) | .523 |
| Gait disorder, n (%) | 399 (41.9) | 299 (39.8) | 100 (49.8) | .013 |
| Walking aid, n (%) | 299 (31.4) | 211 (28.1) | 88 (43.8) | <.001 |
| Falls, n (%) | 394 (41.4) | 314 (41.8) | 80 (39.8) | .629 |
| Parkinsonism, n (%) | 61 (6.4) | 48 (6.4) | 13 (6.5) | 1.0 |
| Dependence in ADL, n (%) | 134 (14.1) | 101 (13.4) | 34 (16.9) | .317 |
| Dependence in iADL, n (%) | 376 (39.5) | 284 (37.8) | 93 (46.3) | .075 |
| Visual impairment, n (%) | 196 (20.6) | 155 (20.6) | 41 (20.4) | 1.0 |
| Hearing impairment, n (%) | 265 (27.8) | 212 (28.2) | 53 (26.4) | .658 |
| . | Total, n = 952 . | SR, n = 751 . | AF, n = 201 . | P . |
|---|---|---|---|---|
| General features | ||||
| Age, median (mean ± SD) | 79 (79.2, 6.2) | 78 (78.7, 6.3) | 81 (81.0, 6.2) | <.001 |
| Female sex, n (%) | 445 (46.7) | 410 (54.6) | 97 (48.3) | .112 |
| Number of prescription drugs, mean (± SD) | 6 (4.2) | 5.8 (4.0) | 8.4 (4.1) | <.001 |
| Systolic bloodpressure, mean (± SD) in mmHg | 151.4 (22.9) | 152.5 (22.4) | 147.3 (24.3) | .006 |
| Diastolic bloodpressure, mean (± SD) in mmHg | 80.4 (11.5) | 81.2 (11.1) | 78.0 (12.3) | .001 |
| Polypharmacy, n (%) | 496 (52.1) | 347 (46.2) | 149 (74.1) | <.001 |
| Hypertension, n (%) | 523 (54.9) | 400 (53.5) | 123 (61.2) | .046 |
| Hypercholesterolemia, n (%) | 187 (19.6) | 148 (19.7) | 39 (19.4) | 1.0 |
| Diabetes mellitus, n (%) | 222 (23.3) | 161 (21.4) | 61 (30.3) | .011 |
| Stroke in medical history, n (%) | 194 (20.4) | 142 (18.9) | 52 (25.9) | .024 |
| Major bleeding in medical history, n (%) | 62 (8.8) | 45 (8.2) | 17 (10.8) | .337 |
| Heart failure, n (%) | 75 (7.9) | 23 (3.1) | 52 (25.9) | <.001 |
| Ischemic heart disease or angina pectoris, n (%) | 196 (20.6) | 139 (18.5) | 57 (28.4) | .003 |
| Peripheral arterial disease, n (%) | 70 (7.4) | 51 (6.8) | 19 (9.5) | .223 |
| Thyroid disease, n (%) | 132 (13.8) | 109 (14.5) | 24 (11.9) | .884 |
| Chronic obstructive pulmonary disease, n (%) | 104 (10.9) | 74 (9.9) | 30 (14.9) | .055 |
| Asthma, n (%) | 53 (5.6) | 39 (5.2) | 14 (7.0) | .385 |
| Obstructive sleep apnoe syndrome, n (%) | 56 (5.9) | 40 (5.3) | 16 (8.0) | .176 |
| Laboratory | ||||
| Hemoglobine level, mean (± SD) in mmol/l | 8.4 (1.0) | 8.5 (1.0) | 8.2 (1.2) | .004 |
| Anaemia, sex adjusted, n (%) | 255 (26.8) | 182 (24.2) | 73 (36.3) | .001 |
| Estimated glomerulal filtration rate, mean (± SD) in ml/min | 69.0 (16.9) | 70.4 (16.1) | 62.5 (19.3) | <.001 |
| Geriatric features | ||||
| FI, mean (± SD) | 0.16 (0.08) | 0.15 (0.08) | 0.19 (0.08) | <.001 |
| Frailty categories | ||||
| Robust, n (%) | 641 (67.3) | 538 (71.6) | 103 (51.2) | <.001 |
| Moderate frailty, n (%) | 175 (18.4) | 127 (16.9) | 48 (23.9) | <.001 |
| Severe frailty, n (%) | 136 (14.3) | 86 (11.5) | 50 (24.9) | <.001 |
| Cognitive function | ||||
| Normal, n (%) | 545 (57.2) | 424 (56.5) | 121 (60.1) | .229 |
| Mild cognitive impairment, n (%) | 272 (28.6) | 213 (28.4) | 59 (29.4) | .229 |
| Dementia, n (%) | 135 (14.2) | 114 (15.2) | 21 (10.4) | .229 |
| MMSE score, mean (± SD) | 26.5 (3.6) | 25.6 (4.1) | 25.9 (3.5) | .417 |
| MoCA score, mean (± SD) | 23.3 (3.8) | 23.7 (4.0) | 23.3 (3.5) | .307 |
| Diminished hand grip strength, n (%) | 152 (16.0) | 118 (15.7) | 35 (17.4) | .523 |
| Gait disorder, n (%) | 399 (41.9) | 299 (39.8) | 100 (49.8) | .013 |
| Walking aid, n (%) | 299 (31.4) | 211 (28.1) | 88 (43.8) | <.001 |
| Falls, n (%) | 394 (41.4) | 314 (41.8) | 80 (39.8) | .629 |
| Parkinsonism, n (%) | 61 (6.4) | 48 (6.4) | 13 (6.5) | 1.0 |
| Dependence in ADL, n (%) | 134 (14.1) | 101 (13.4) | 34 (16.9) | .317 |
| Dependence in iADL, n (%) | 376 (39.5) | 284 (37.8) | 93 (46.3) | .075 |
| Visual impairment, n (%) | 196 (20.6) | 155 (20.6) | 41 (20.4) | 1.0 |
| Hearing impairment, n (%) | 265 (27.8) | 212 (28.2) | 53 (26.4) | .658 |
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