Demographic and perinatal data of patients with central congenital hypothyroidism
| . | All . | MPHD . | ICCH . | P value . |
|---|---|---|---|---|
| No. (%) | 94 (100) | 79 (84) | 15 (16) | |
| Male (%) | 54 (57) | 42 (53) | 12 (80) | .05 |
| Consanguinity (%) | 21 (22) | 19 (24.4) | 2 (12.3) | .3 |
| Other cases in the family (%) | 13 (14.5) | 5 (6.4) | 8 (53.3) | .001 |
| Gestational age, weeks | 38.8 ± 2.9 | 38.6 ± 3.1 | 36.6 ± 4.8 | NS |
| Birth weight, SDS | −0.49 ± 1.2 | −0.6 ± 1.2 | 0.1 ± 1.4 | NS |
| Age at diagnosis, days | 50 (1-8760) | 55.5 (2-8660) | 45.5 (1-2190) | NS |
| Early diagnosis before 14 days | 28 (30) | 24 (30) | 4 (27) | .80 |
| Late diagnosis after 14 days | 66 (70) | 55 (70) | 11 (73) | .81 |
| . | All . | MPHD . | ICCH . | P value . |
|---|---|---|---|---|
| No. (%) | 94 (100) | 79 (84) | 15 (16) | |
| Male (%) | 54 (57) | 42 (53) | 12 (80) | .05 |
| Consanguinity (%) | 21 (22) | 19 (24.4) | 2 (12.3) | .3 |
| Other cases in the family (%) | 13 (14.5) | 5 (6.4) | 8 (53.3) | .001 |
| Gestational age, weeks | 38.8 ± 2.9 | 38.6 ± 3.1 | 36.6 ± 4.8 | NS |
| Birth weight, SDS | −0.49 ± 1.2 | −0.6 ± 1.2 | 0.1 ± 1.4 | NS |
| Age at diagnosis, days | 50 (1-8760) | 55.5 (2-8660) | 45.5 (1-2190) | NS |
| Early diagnosis before 14 days | 28 (30) | 24 (30) | 4 (27) | .80 |
| Late diagnosis after 14 days | 66 (70) | 55 (70) | 11 (73) | .81 |
Numbers represent n (%), median (range), or mean (±SD). P values below .05 are shown in bold type.
Abbreviations: ICCH, isolated congenital central hypothyroidism; MPHD, multiple pituitary hormone deficiency; SDS, standard deviation score.
Demographic and perinatal data of patients with central congenital hypothyroidism
| . | All . | MPHD . | ICCH . | P value . |
|---|---|---|---|---|
| No. (%) | 94 (100) | 79 (84) | 15 (16) | |
| Male (%) | 54 (57) | 42 (53) | 12 (80) | .05 |
| Consanguinity (%) | 21 (22) | 19 (24.4) | 2 (12.3) | .3 |
| Other cases in the family (%) | 13 (14.5) | 5 (6.4) | 8 (53.3) | .001 |
| Gestational age, weeks | 38.8 ± 2.9 | 38.6 ± 3.1 | 36.6 ± 4.8 | NS |
| Birth weight, SDS | −0.49 ± 1.2 | −0.6 ± 1.2 | 0.1 ± 1.4 | NS |
| Age at diagnosis, days | 50 (1-8760) | 55.5 (2-8660) | 45.5 (1-2190) | NS |
| Early diagnosis before 14 days | 28 (30) | 24 (30) | 4 (27) | .80 |
| Late diagnosis after 14 days | 66 (70) | 55 (70) | 11 (73) | .81 |
| . | All . | MPHD . | ICCH . | P value . |
|---|---|---|---|---|
| No. (%) | 94 (100) | 79 (84) | 15 (16) | |
| Male (%) | 54 (57) | 42 (53) | 12 (80) | .05 |
| Consanguinity (%) | 21 (22) | 19 (24.4) | 2 (12.3) | .3 |
| Other cases in the family (%) | 13 (14.5) | 5 (6.4) | 8 (53.3) | .001 |
| Gestational age, weeks | 38.8 ± 2.9 | 38.6 ± 3.1 | 36.6 ± 4.8 | NS |
| Birth weight, SDS | −0.49 ± 1.2 | −0.6 ± 1.2 | 0.1 ± 1.4 | NS |
| Age at diagnosis, days | 50 (1-8760) | 55.5 (2-8660) | 45.5 (1-2190) | NS |
| Early diagnosis before 14 days | 28 (30) | 24 (30) | 4 (27) | .80 |
| Late diagnosis after 14 days | 66 (70) | 55 (70) | 11 (73) | .81 |
Numbers represent n (%), median (range), or mean (±SD). P values below .05 are shown in bold type.
Abbreviations: ICCH, isolated congenital central hypothyroidism; MPHD, multiple pituitary hormone deficiency; SDS, standard deviation score.
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