Table 3

Different sodium channel blocker agents utilised in sodium channel blocker testing

Generic nameDrug classHalf-lifeCommentsReferences
Ajmaline1A∼5 minMaximal dose 1 mg/kg up to 100 mg, infused continuously over 5–10 min or in boluses 10 mg/min5,17,61,65,66
Flecainide1C∼13–16 hMaximal dose 2 mg/kg up to 150 mg, either continuously over 10 min or in boluses of 10 mg/min17,19,31,67
Pilsicainide1C∼3–6 hMaximal dose 1 mg/kg, infused continuously over 5–10 min or in boluses 10 mg/min62,68–70
Procainamide1A∼3–5 hMaximal dose 15–18 mg/kg or 1000 mg, either continuously over 5–20 min or in boluses achieving a rate of 100 mg/min20,63,65,71
Generic nameDrug classHalf-lifeCommentsReferences
Ajmaline1A∼5 minMaximal dose 1 mg/kg up to 100 mg, infused continuously over 5–10 min or in boluses 10 mg/min5,17,61,65,66
Flecainide1C∼13–16 hMaximal dose 2 mg/kg up to 150 mg, either continuously over 10 min or in boluses of 10 mg/min17,19,31,67
Pilsicainide1C∼3–6 hMaximal dose 1 mg/kg, infused continuously over 5–10 min or in boluses 10 mg/min62,68–70
Procainamide1A∼3–5 hMaximal dose 15–18 mg/kg or 1000 mg, either continuously over 5–20 min or in boluses achieving a rate of 100 mg/min20,63,65,71
Table 3

Different sodium channel blocker agents utilised in sodium channel blocker testing

Generic nameDrug classHalf-lifeCommentsReferences
Ajmaline1A∼5 minMaximal dose 1 mg/kg up to 100 mg, infused continuously over 5–10 min or in boluses 10 mg/min5,17,61,65,66
Flecainide1C∼13–16 hMaximal dose 2 mg/kg up to 150 mg, either continuously over 10 min or in boluses of 10 mg/min17,19,31,67
Pilsicainide1C∼3–6 hMaximal dose 1 mg/kg, infused continuously over 5–10 min or in boluses 10 mg/min62,68–70
Procainamide1A∼3–5 hMaximal dose 15–18 mg/kg or 1000 mg, either continuously over 5–20 min or in boluses achieving a rate of 100 mg/min20,63,65,71
Generic nameDrug classHalf-lifeCommentsReferences
Ajmaline1A∼5 minMaximal dose 1 mg/kg up to 100 mg, infused continuously over 5–10 min or in boluses 10 mg/min5,17,61,65,66
Flecainide1C∼13–16 hMaximal dose 2 mg/kg up to 150 mg, either continuously over 10 min or in boluses of 10 mg/min17,19,31,67
Pilsicainide1C∼3–6 hMaximal dose 1 mg/kg, infused continuously over 5–10 min or in boluses 10 mg/min62,68–70
Procainamide1A∼3–5 hMaximal dose 15–18 mg/kg or 1000 mg, either continuously over 5–20 min or in boluses achieving a rate of 100 mg/min20,63,65,71
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