Different sodium channel blocker agents utilised in sodium channel blocker testing
Generic name . | Drug class . | Half-life . | Comments . | References . |
---|---|---|---|---|
Ajmaline | 1A | ∼5 min | Maximal dose 1 mg/kg up to 100 mg, infused continuously over 5–10 min or in boluses 10 mg/min | 5,17,61,65,66 |
Flecainide | 1C | ∼13–16 h | Maximal dose 2 mg/kg up to 150 mg, either continuously over 10 min or in boluses of 10 mg/min | 17,19,31,67 |
Pilsicainide | 1C | ∼3–6 h | Maximal dose 1 mg/kg, infused continuously over 5–10 min or in boluses 10 mg/min | 62,68–70 |
Procainamide | 1A | ∼3–5 h | Maximal dose 15–18 mg/kg or 1000 mg, either continuously over 5–20 min or in boluses achieving a rate of 100 mg/min | 20,63,65,71 |
Generic name . | Drug class . | Half-life . | Comments . | References . |
---|---|---|---|---|
Ajmaline | 1A | ∼5 min | Maximal dose 1 mg/kg up to 100 mg, infused continuously over 5–10 min or in boluses 10 mg/min | 5,17,61,65,66 |
Flecainide | 1C | ∼13–16 h | Maximal dose 2 mg/kg up to 150 mg, either continuously over 10 min or in boluses of 10 mg/min | 17,19,31,67 |
Pilsicainide | 1C | ∼3–6 h | Maximal dose 1 mg/kg, infused continuously over 5–10 min or in boluses 10 mg/min | 62,68–70 |
Procainamide | 1A | ∼3–5 h | Maximal dose 15–18 mg/kg or 1000 mg, either continuously over 5–20 min or in boluses achieving a rate of 100 mg/min | 20,63,65,71 |
Different sodium channel blocker agents utilised in sodium channel blocker testing
Generic name . | Drug class . | Half-life . | Comments . | References . |
---|---|---|---|---|
Ajmaline | 1A | ∼5 min | Maximal dose 1 mg/kg up to 100 mg, infused continuously over 5–10 min or in boluses 10 mg/min | 5,17,61,65,66 |
Flecainide | 1C | ∼13–16 h | Maximal dose 2 mg/kg up to 150 mg, either continuously over 10 min or in boluses of 10 mg/min | 17,19,31,67 |
Pilsicainide | 1C | ∼3–6 h | Maximal dose 1 mg/kg, infused continuously over 5–10 min or in boluses 10 mg/min | 62,68–70 |
Procainamide | 1A | ∼3–5 h | Maximal dose 15–18 mg/kg or 1000 mg, either continuously over 5–20 min or in boluses achieving a rate of 100 mg/min | 20,63,65,71 |
Generic name . | Drug class . | Half-life . | Comments . | References . |
---|---|---|---|---|
Ajmaline | 1A | ∼5 min | Maximal dose 1 mg/kg up to 100 mg, infused continuously over 5–10 min or in boluses 10 mg/min | 5,17,61,65,66 |
Flecainide | 1C | ∼13–16 h | Maximal dose 2 mg/kg up to 150 mg, either continuously over 10 min or in boluses of 10 mg/min | 17,19,31,67 |
Pilsicainide | 1C | ∼3–6 h | Maximal dose 1 mg/kg, infused continuously over 5–10 min or in boluses 10 mg/min | 62,68–70 |
Procainamide | 1A | ∼3–5 h | Maximal dose 15–18 mg/kg or 1000 mg, either continuously over 5–20 min or in boluses achieving a rate of 100 mg/min | 20,63,65,71 |
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