Table 4
Open in new tab

 Protocols for epinephrine testing

Progressive protocol (‘Mayo’)
Baseline ECG—resting supine for 10 min in a quiet room
Intravenous epinephrine infusion:

  • Commence at 0.025 µg/(kg/min) for 10 min

  • Increased to 0.05, then 0.10, and finally 0.20 µg/(kg/min) at 5-min intervals

  • Cease infusion after 5 min of 0.20 µg/(kg/min) or earlier if SBP >200 mmHg, or occurrence of VT, 10 PVCs/min, T wave alternans or patient intolerance

Progressive protocol (‘Mayo’)
Baseline ECG—resting supine for 10 min in a quiet room
Intravenous epinephrine infusion:

  • Commence at 0.025 µg/(kg/min) for 10 min

  • Increased to 0.05, then 0.10, and finally 0.20 µg/(kg/min) at 5-min intervals

  • Cease infusion after 5 min of 0.20 µg/(kg/min) or earlier if SBP >200 mmHg, or occurrence of VT, 10 PVCs/min, T wave alternans or patient intolerance

Bolus protocol (‘Shimizu’)
Intravenous epinephrine infusion:

  • Bolus of 0.10 µg/kg intravenous epinephrine

  • Followed by 0.10 µg/(kg/min) infusion for 5 min

Bolus protocol (‘Shimizu’)
Intravenous epinephrine infusion:

  • Bolus of 0.10 µg/kg intravenous epinephrine

  • Followed by 0.10 µg/(kg/min) infusion for 5 min

VT, ventricular tachycardia.

Table 4
Open in new tab

 Protocols for epinephrine testing

Progressive protocol (‘Mayo’)
Baseline ECG—resting supine for 10 min in a quiet room
Intravenous epinephrine infusion:

  • Commence at 0.025 µg/(kg/min) for 10 min

  • Increased to 0.05, then 0.10, and finally 0.20 µg/(kg/min) at 5-min intervals

  • Cease infusion after 5 min of 0.20 µg/(kg/min) or earlier if SBP >200 mmHg, or occurrence of VT, 10 PVCs/min, T wave alternans or patient intolerance

Progressive protocol (‘Mayo’)
Baseline ECG—resting supine for 10 min in a quiet room
Intravenous epinephrine infusion:

  • Commence at 0.025 µg/(kg/min) for 10 min

  • Increased to 0.05, then 0.10, and finally 0.20 µg/(kg/min) at 5-min intervals

  • Cease infusion after 5 min of 0.20 µg/(kg/min) or earlier if SBP >200 mmHg, or occurrence of VT, 10 PVCs/min, T wave alternans or patient intolerance

Bolus protocol (‘Shimizu’)
Intravenous epinephrine infusion:

  • Bolus of 0.10 µg/kg intravenous epinephrine

  • Followed by 0.10 µg/(kg/min) infusion for 5 min

Bolus protocol (‘Shimizu’)
Intravenous epinephrine infusion:

  • Bolus of 0.10 µg/kg intravenous epinephrine

  • Followed by 0.10 µg/(kg/min) infusion for 5 min

VT, ventricular tachycardia.

Close
This Feature Is Available To Subscribers Only

Sign In or Create an Account

Close

This PDF is available to Subscribers Only

View Article Abstract & Purchase Options

For full access to this pdf, sign in to an existing account, or purchase an annual subscription.

Close