Table 4

Lipid metabolic processes disrupted in preterm placentas

Functionsp-valuez-scoreDifferentially expressed gene number
Black male preterm placentas
Release of lipid and fatty acid2.98E-071.0714
Synthesis of PAF3.17E-072.206
Concentration of eicosanoid1.22E-061.4611
Release of eicosanoid2.39E-061.6811
Fatty acid metabolism3.45E-060.9927
Concentration of lipid & fatty acid5.92E-061.0034
Binding of lipid1.37E-05−0.318
Synthesis of leukotriene3.35E-051.577
Concentration of ARA5.03E-051.505
Secretion of fatty acid5.29E-050.007
Synthesis of eicosanoid5.34E-051.7813
Synthesis of fatty acid7.04E-051.7616
Concentration of acylglycerol7.83E-050.5418
Black female preterm placentas
Synthesis of eicosanoid1.45E-051.0311
Quantity of polyunsaturated fatty acids3.09E-05−0.608
Concentration of eicosanoid1.09E-04−0.357
Release of lipid1.11E-041.259
Release of eicosanoid1.67E-041.427
Synthesis of prostaglandin2.72E-041.828
Concentration of prostaglandin4.87E-040.255
Release of ARA4.87E-041.545
Synthesis of lipid5.32E-040.4720
Fatty acid metabolism6.84E-040.3316
White male preterm placentas
Quantity of disaturated PC5.84E-03na1
Synthesis of eicosanoid6.04E-03−0.325
Phospholipid flip-flop of phosphatidylserine6.12E-03na2
White female preterm placentas
Synthesis of PAF2.32E-06na4
Quantity of leukotriene8.89E-06na4
Synthesis of thromboxane B22.53E-05na3
Production of prostaglandin F13.93E-05na2
Synthesis of eicosanoid1.61E-042.027
Synthesis of lipid1.88E-041.4914
Synthesis of leukotriene2.32E-04na4
Phospholipid flip-flop of phosphatidylserine2.36E-04na3
Concentration of eicosanoid2.61E-041.195
Synthesis of prostaglandin D23.33E-04na3
Release of lipid4.40E-041.956
Secretion of prostaglandin4.52E-04na3
Functionsp-valuez-scoreDifferentially expressed gene number
Black male preterm placentas
Release of lipid and fatty acid2.98E-071.0714
Synthesis of PAF3.17E-072.206
Concentration of eicosanoid1.22E-061.4611
Release of eicosanoid2.39E-061.6811
Fatty acid metabolism3.45E-060.9927
Concentration of lipid & fatty acid5.92E-061.0034
Binding of lipid1.37E-05−0.318
Synthesis of leukotriene3.35E-051.577
Concentration of ARA5.03E-051.505
Secretion of fatty acid5.29E-050.007
Synthesis of eicosanoid5.34E-051.7813
Synthesis of fatty acid7.04E-051.7616
Concentration of acylglycerol7.83E-050.5418
Black female preterm placentas
Synthesis of eicosanoid1.45E-051.0311
Quantity of polyunsaturated fatty acids3.09E-05−0.608
Concentration of eicosanoid1.09E-04−0.357
Release of lipid1.11E-041.259
Release of eicosanoid1.67E-041.427
Synthesis of prostaglandin2.72E-041.828
Concentration of prostaglandin4.87E-040.255
Release of ARA4.87E-041.545
Synthesis of lipid5.32E-040.4720
Fatty acid metabolism6.84E-040.3316
White male preterm placentas
Quantity of disaturated PC5.84E-03na1
Synthesis of eicosanoid6.04E-03−0.325
Phospholipid flip-flop of phosphatidylserine6.12E-03na2
White female preterm placentas
Synthesis of PAF2.32E-06na4
Quantity of leukotriene8.89E-06na4
Synthesis of thromboxane B22.53E-05na3
Production of prostaglandin F13.93E-05na2
Synthesis of eicosanoid1.61E-042.027
Synthesis of lipid1.88E-041.4914
Synthesis of leukotriene2.32E-04na4
Phospholipid flip-flop of phosphatidylserine2.36E-04na3
Concentration of eicosanoid2.61E-041.195
Synthesis of prostaglandin D23.33E-04na3
Release of lipid4.40E-041.956
Secretion of prostaglandin4.52E-04na3
Table 4

Lipid metabolic processes disrupted in preterm placentas

Functionsp-valuez-scoreDifferentially expressed gene number
Black male preterm placentas
Release of lipid and fatty acid2.98E-071.0714
Synthesis of PAF3.17E-072.206
Concentration of eicosanoid1.22E-061.4611
Release of eicosanoid2.39E-061.6811
Fatty acid metabolism3.45E-060.9927
Concentration of lipid & fatty acid5.92E-061.0034
Binding of lipid1.37E-05−0.318
Synthesis of leukotriene3.35E-051.577
Concentration of ARA5.03E-051.505
Secretion of fatty acid5.29E-050.007
Synthesis of eicosanoid5.34E-051.7813
Synthesis of fatty acid7.04E-051.7616
Concentration of acylglycerol7.83E-050.5418
Black female preterm placentas
Synthesis of eicosanoid1.45E-051.0311
Quantity of polyunsaturated fatty acids3.09E-05−0.608
Concentration of eicosanoid1.09E-04−0.357
Release of lipid1.11E-041.259
Release of eicosanoid1.67E-041.427
Synthesis of prostaglandin2.72E-041.828
Concentration of prostaglandin4.87E-040.255
Release of ARA4.87E-041.545
Synthesis of lipid5.32E-040.4720
Fatty acid metabolism6.84E-040.3316
White male preterm placentas
Quantity of disaturated PC5.84E-03na1
Synthesis of eicosanoid6.04E-03−0.325
Phospholipid flip-flop of phosphatidylserine6.12E-03na2
White female preterm placentas
Synthesis of PAF2.32E-06na4
Quantity of leukotriene8.89E-06na4
Synthesis of thromboxane B22.53E-05na3
Production of prostaglandin F13.93E-05na2
Synthesis of eicosanoid1.61E-042.027
Synthesis of lipid1.88E-041.4914
Synthesis of leukotriene2.32E-04na4
Phospholipid flip-flop of phosphatidylserine2.36E-04na3
Concentration of eicosanoid2.61E-041.195
Synthesis of prostaglandin D23.33E-04na3
Release of lipid4.40E-041.956
Secretion of prostaglandin4.52E-04na3
Functionsp-valuez-scoreDifferentially expressed gene number
Black male preterm placentas
Release of lipid and fatty acid2.98E-071.0714
Synthesis of PAF3.17E-072.206
Concentration of eicosanoid1.22E-061.4611
Release of eicosanoid2.39E-061.6811
Fatty acid metabolism3.45E-060.9927
Concentration of lipid & fatty acid5.92E-061.0034
Binding of lipid1.37E-05−0.318
Synthesis of leukotriene3.35E-051.577
Concentration of ARA5.03E-051.505
Secretion of fatty acid5.29E-050.007
Synthesis of eicosanoid5.34E-051.7813
Synthesis of fatty acid7.04E-051.7616
Concentration of acylglycerol7.83E-050.5418
Black female preterm placentas
Synthesis of eicosanoid1.45E-051.0311
Quantity of polyunsaturated fatty acids3.09E-05−0.608
Concentration of eicosanoid1.09E-04−0.357
Release of lipid1.11E-041.259
Release of eicosanoid1.67E-041.427
Synthesis of prostaglandin2.72E-041.828
Concentration of prostaglandin4.87E-040.255
Release of ARA4.87E-041.545
Synthesis of lipid5.32E-040.4720
Fatty acid metabolism6.84E-040.3316
White male preterm placentas
Quantity of disaturated PC5.84E-03na1
Synthesis of eicosanoid6.04E-03−0.325
Phospholipid flip-flop of phosphatidylserine6.12E-03na2
White female preterm placentas
Synthesis of PAF2.32E-06na4
Quantity of leukotriene8.89E-06na4
Synthesis of thromboxane B22.53E-05na3
Production of prostaglandin F13.93E-05na2
Synthesis of eicosanoid1.61E-042.027
Synthesis of lipid1.88E-041.4914
Synthesis of leukotriene2.32E-04na4
Phospholipid flip-flop of phosphatidylserine2.36E-04na3
Concentration of eicosanoid2.61E-041.195
Synthesis of prostaglandin D23.33E-04na3
Release of lipid4.40E-041.956
Secretion of prostaglandin4.52E-04na3
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