Main Findings on the Relationship Between Vitamin D Receptor Gene Polymorphisms and Metabolic Markers
| Genotype . | Author (year) . | Main finding . |
|---|---|---|
| Fokl rs 2228570 | ||
| ff | Hossein-nezhad et al. (2009)31 | Associated with higher %HbA1c and HOMA-IR |
| Mackway and Badawi, (2014)32 | Associated with higher TAG, LDL-C, IL-6, and lower HDL-C | |
| Ff | Hossein-nezhad et al. (2009)31 | Associated with higher %HbA1c |
| Angel et al. (2016)30 | Associated with higher TAG and HOMA-IR | |
| Mackway and Badawi, (2014)32 | Associated with higher TC | |
| Bsml rs1544410 | ||
| Bb | Safar et al. (2017)33 | Associated with higher LDL-C |
| Taql rs731236 | ||
| TT | Safar et al. (2017)33 | Associated with higher TC and LDL-C |
| Tt | Safar et al. (2017)33 | Associated with TC and LDL-C |
| Genotype . | Author (year) . | Main finding . |
|---|---|---|
| Fokl rs 2228570 | ||
| ff | Hossein-nezhad et al. (2009)31 | Associated with higher %HbA1c and HOMA-IR |
| Mackway and Badawi, (2014)32 | Associated with higher TAG, LDL-C, IL-6, and lower HDL-C | |
| Ff | Hossein-nezhad et al. (2009)31 | Associated with higher %HbA1c |
| Angel et al. (2016)30 | Associated with higher TAG and HOMA-IR | |
| Mackway and Badawi, (2014)32 | Associated with higher TC | |
| Bsml rs1544410 | ||
| Bb | Safar et al. (2017)33 | Associated with higher LDL-C |
| Taql rs731236 | ||
| TT | Safar et al. (2017)33 | Associated with higher TC and LDL-C |
| Tt | Safar et al. (2017)33 | Associated with TC and LDL-C |
Abbreviations: ff and TT, homozygote polymorphic; Ff, Bb, and Tt, heterozygote polymorphic; HDL, high-density lipoprotein; HOMA-IR, homeostatic model asessment for insulin resistance; IL-6, interleukin 6; LDL-C, low-density lipoprotein cholesterol; TAG, triacylglycerol; TC, total cholesterol; %HbA1c, hemoglobin A1c percentage.
Main Findings on the Relationship Between Vitamin D Receptor Gene Polymorphisms and Metabolic Markers
| Genotype . | Author (year) . | Main finding . |
|---|---|---|
| Fokl rs 2228570 | ||
| ff | Hossein-nezhad et al. (2009)31 | Associated with higher %HbA1c and HOMA-IR |
| Mackway and Badawi, (2014)32 | Associated with higher TAG, LDL-C, IL-6, and lower HDL-C | |
| Ff | Hossein-nezhad et al. (2009)31 | Associated with higher %HbA1c |
| Angel et al. (2016)30 | Associated with higher TAG and HOMA-IR | |
| Mackway and Badawi, (2014)32 | Associated with higher TC | |
| Bsml rs1544410 | ||
| Bb | Safar et al. (2017)33 | Associated with higher LDL-C |
| Taql rs731236 | ||
| TT | Safar et al. (2017)33 | Associated with higher TC and LDL-C |
| Tt | Safar et al. (2017)33 | Associated with TC and LDL-C |
| Genotype . | Author (year) . | Main finding . |
|---|---|---|
| Fokl rs 2228570 | ||
| ff | Hossein-nezhad et al. (2009)31 | Associated with higher %HbA1c and HOMA-IR |
| Mackway and Badawi, (2014)32 | Associated with higher TAG, LDL-C, IL-6, and lower HDL-C | |
| Ff | Hossein-nezhad et al. (2009)31 | Associated with higher %HbA1c |
| Angel et al. (2016)30 | Associated with higher TAG and HOMA-IR | |
| Mackway and Badawi, (2014)32 | Associated with higher TC | |
| Bsml rs1544410 | ||
| Bb | Safar et al. (2017)33 | Associated with higher LDL-C |
| Taql rs731236 | ||
| TT | Safar et al. (2017)33 | Associated with higher TC and LDL-C |
| Tt | Safar et al. (2017)33 | Associated with TC and LDL-C |
Abbreviations: ff and TT, homozygote polymorphic; Ff, Bb, and Tt, heterozygote polymorphic; HDL, high-density lipoprotein; HOMA-IR, homeostatic model asessment for insulin resistance; IL-6, interleukin 6; LDL-C, low-density lipoprotein cholesterol; TAG, triacylglycerol; TC, total cholesterol; %HbA1c, hemoglobin A1c percentage.
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