Functional outcomes at 6-month follow-up (overall and stratified by type of surgery)
. | Overall (n = 207) . | Surgical drainage procedures(n = 51) . | DPPHRs (n = 61) . | Formal pancreatic resections (n = 95) . | P . |
---|---|---|---|---|---|
Primary outcomes | |||||
Izbicki pain score at 6-month follow-up, median (i.q.r.)* | 19.0 (0.0–33.5) | 19.0 (0.0–31.0) | 15.0 (0.0–33.8) | 21.0 (1.5–34.0) | 0.428§ |
Pain relief at 6-month follow-up* | 82 (72.6) | 20 (74) | 26 (68) | 36 (75) | 0.502¶ |
Complete | 43 (38.1) | 10 (37) | 18 (47) | 15 (31) | 0.308¶ |
Partial | 39 (34.5) | 10 (59) | 8 (40) | 21 (64) | 0.248¶ |
Secondary outcomes | |||||
VAS score at 6-month follow-up, median (i.q.r.)* | 2.0 (0.0–26.0) | 10.0 (1.0–30.0) | 1.5 (0.0–30.0) | 1.0 (0.0–20.0) | 0.099§ |
Change from baseline to 6-month follow-up | |||||
VAS score, median (i.q.r.)* | 53.5 (30.0–77.0) | 50.0 (31.0–71.0) | 52.0 (21.0–78.0) | 60.0 (35.0–80.0) | 0.253§ |
PANQOLI score, mean(s.d.)† | 24.4 (22.3) | 25.4 (25.1) | 27.8 (21.6) | 21.7 (21.3) | 0.290# |
SF-12 score, mean(s.d.)‡ | |||||
Physical Component Summary score | 14.4 (14.8) | 14.9 (18.4) | 16.4 (15.8) | 13.0 (12.7) | 0.442# |
Mental Component Summary score | −4.6 (9.5) | 12.8 (15.3) | 12.4 (12.4) | 12.0 (12.7) | 0.951# |
. | Overall (n = 207) . | Surgical drainage procedures(n = 51) . | DPPHRs (n = 61) . | Formal pancreatic resections (n = 95) . | P . |
---|---|---|---|---|---|
Primary outcomes | |||||
Izbicki pain score at 6-month follow-up, median (i.q.r.)* | 19.0 (0.0–33.5) | 19.0 (0.0–31.0) | 15.0 (0.0–33.8) | 21.0 (1.5–34.0) | 0.428§ |
Pain relief at 6-month follow-up* | 82 (72.6) | 20 (74) | 26 (68) | 36 (75) | 0.502¶ |
Complete | 43 (38.1) | 10 (37) | 18 (47) | 15 (31) | 0.308¶ |
Partial | 39 (34.5) | 10 (59) | 8 (40) | 21 (64) | 0.248¶ |
Secondary outcomes | |||||
VAS score at 6-month follow-up, median (i.q.r.)* | 2.0 (0.0–26.0) | 10.0 (1.0–30.0) | 1.5 (0.0–30.0) | 1.0 (0.0–20.0) | 0.099§ |
Change from baseline to 6-month follow-up | |||||
VAS score, median (i.q.r.)* | 53.5 (30.0–77.0) | 50.0 (31.0–71.0) | 52.0 (21.0–78.0) | 60.0 (35.0–80.0) | 0.253§ |
PANQOLI score, mean(s.d.)† | 24.4 (22.3) | 25.4 (25.1) | 27.8 (21.6) | 21.7 (21.3) | 0.290# |
SF-12 score, mean(s.d.)‡ | |||||
Physical Component Summary score | 14.4 (14.8) | 14.9 (18.4) | 16.4 (15.8) | 13.0 (12.7) | 0.442# |
Mental Component Summary score | −4.6 (9.5) | 12.8 (15.3) | 12.4 (12.4) | 12.0 (12.7) | 0.951# |
Values are n (%) unless otherwise indicated. All percentages reflect the total number of patients per subgroup, including patients with missing information. *Only calculated for patients with pain as an indication for surgery and with complete questionnaires at baseline and 6-month follow-up (113 patients). †Only calculated for patients with complete questionnaires at baseline and 6-month follow-up (170 patients). ‡Only calculated for patients with complete questionnaires at baseline and 6-month follow-up (168 patients). §A Kruskall–Wallis test was used for data with a non-normal distribution. ¶A chi-squared test or Fisher’s exact test was used for categorical variables. #One-way ANOVA was used for data with a normal distribution. DPPHRs, duodenum-preserving pancreatic head resections; i.q.r., interquartile range; VAS, Visual Analogue Scale; PANQOLI, Pancreatitis Quality of Life Instrument; SF-12, 12-Item Short-Form.
Functional outcomes at 6-month follow-up (overall and stratified by type of surgery)
. | Overall (n = 207) . | Surgical drainage procedures(n = 51) . | DPPHRs (n = 61) . | Formal pancreatic resections (n = 95) . | P . |
---|---|---|---|---|---|
Primary outcomes | |||||
Izbicki pain score at 6-month follow-up, median (i.q.r.)* | 19.0 (0.0–33.5) | 19.0 (0.0–31.0) | 15.0 (0.0–33.8) | 21.0 (1.5–34.0) | 0.428§ |
Pain relief at 6-month follow-up* | 82 (72.6) | 20 (74) | 26 (68) | 36 (75) | 0.502¶ |
Complete | 43 (38.1) | 10 (37) | 18 (47) | 15 (31) | 0.308¶ |
Partial | 39 (34.5) | 10 (59) | 8 (40) | 21 (64) | 0.248¶ |
Secondary outcomes | |||||
VAS score at 6-month follow-up, median (i.q.r.)* | 2.0 (0.0–26.0) | 10.0 (1.0–30.0) | 1.5 (0.0–30.0) | 1.0 (0.0–20.0) | 0.099§ |
Change from baseline to 6-month follow-up | |||||
VAS score, median (i.q.r.)* | 53.5 (30.0–77.0) | 50.0 (31.0–71.0) | 52.0 (21.0–78.0) | 60.0 (35.0–80.0) | 0.253§ |
PANQOLI score, mean(s.d.)† | 24.4 (22.3) | 25.4 (25.1) | 27.8 (21.6) | 21.7 (21.3) | 0.290# |
SF-12 score, mean(s.d.)‡ | |||||
Physical Component Summary score | 14.4 (14.8) | 14.9 (18.4) | 16.4 (15.8) | 13.0 (12.7) | 0.442# |
Mental Component Summary score | −4.6 (9.5) | 12.8 (15.3) | 12.4 (12.4) | 12.0 (12.7) | 0.951# |
. | Overall (n = 207) . | Surgical drainage procedures(n = 51) . | DPPHRs (n = 61) . | Formal pancreatic resections (n = 95) . | P . |
---|---|---|---|---|---|
Primary outcomes | |||||
Izbicki pain score at 6-month follow-up, median (i.q.r.)* | 19.0 (0.0–33.5) | 19.0 (0.0–31.0) | 15.0 (0.0–33.8) | 21.0 (1.5–34.0) | 0.428§ |
Pain relief at 6-month follow-up* | 82 (72.6) | 20 (74) | 26 (68) | 36 (75) | 0.502¶ |
Complete | 43 (38.1) | 10 (37) | 18 (47) | 15 (31) | 0.308¶ |
Partial | 39 (34.5) | 10 (59) | 8 (40) | 21 (64) | 0.248¶ |
Secondary outcomes | |||||
VAS score at 6-month follow-up, median (i.q.r.)* | 2.0 (0.0–26.0) | 10.0 (1.0–30.0) | 1.5 (0.0–30.0) | 1.0 (0.0–20.0) | 0.099§ |
Change from baseline to 6-month follow-up | |||||
VAS score, median (i.q.r.)* | 53.5 (30.0–77.0) | 50.0 (31.0–71.0) | 52.0 (21.0–78.0) | 60.0 (35.0–80.0) | 0.253§ |
PANQOLI score, mean(s.d.)† | 24.4 (22.3) | 25.4 (25.1) | 27.8 (21.6) | 21.7 (21.3) | 0.290# |
SF-12 score, mean(s.d.)‡ | |||||
Physical Component Summary score | 14.4 (14.8) | 14.9 (18.4) | 16.4 (15.8) | 13.0 (12.7) | 0.442# |
Mental Component Summary score | −4.6 (9.5) | 12.8 (15.3) | 12.4 (12.4) | 12.0 (12.7) | 0.951# |
Values are n (%) unless otherwise indicated. All percentages reflect the total number of patients per subgroup, including patients with missing information. *Only calculated for patients with pain as an indication for surgery and with complete questionnaires at baseline and 6-month follow-up (113 patients). †Only calculated for patients with complete questionnaires at baseline and 6-month follow-up (170 patients). ‡Only calculated for patients with complete questionnaires at baseline and 6-month follow-up (168 patients). §A Kruskall–Wallis test was used for data with a non-normal distribution. ¶A chi-squared test or Fisher’s exact test was used for categorical variables. #One-way ANOVA was used for data with a normal distribution. DPPHRs, duodenum-preserving pancreatic head resections; i.q.r., interquartile range; VAS, Visual Analogue Scale; PANQOLI, Pancreatitis Quality of Life Instrument; SF-12, 12-Item Short-Form.
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