Table 4.

Predictive factors of impaired response to COH (≤ 9 MII oocytes) for fertility preservation before lymphoma treatment.

Disease characteristicOR (95% CI)P-value
Lymphoma0.2
 HodgkinReference
 Non-Hodgkin1.2 (0.9–1.7)
Ann-Arbor stage0.9
 I–II (localized)Reference
 III–IV (disseminated)1.0 (0.7–1.4)
Adverse clinical symptoms0.7
 Yes0.9 (0.7–1.3)
 NoReference
Adverse biological parameters0.1
 Yes0.9 (0.7–1.3)
 NoReference
ECOG-PS0.9
 0Reference
 ≥10.9 (0.7–1.4)
Disease characteristicOR (95% CI)P-value
Lymphoma0.2
 HodgkinReference
 Non-Hodgkin1.2 (0.9–1.7)
Ann-Arbor stage0.9
 I–II (localized)Reference
 III–IV (disseminated)1.0 (0.7–1.4)
Adverse clinical symptoms0.7
 Yes0.9 (0.7–1.3)
 NoReference
Adverse biological parameters0.1
 Yes0.9 (0.7–1.3)
 NoReference
ECOG-PS0.9
 0Reference
 ≥10.9 (0.7–1.4)

COH, ovarian stimulation; MII, metaphase II; OR, odds ratio; ECOG-PS, Eastern Cooperative Oncology Group Performance Status.

All results were adjusted for POSEIDON criteria before ovarian stimulation (Groups 3 and 4).

Table 4.

Predictive factors of impaired response to COH (≤ 9 MII oocytes) for fertility preservation before lymphoma treatment.

Disease characteristicOR (95% CI)P-value
Lymphoma0.2
 HodgkinReference
 Non-Hodgkin1.2 (0.9–1.7)
Ann-Arbor stage0.9
 I–II (localized)Reference
 III–IV (disseminated)1.0 (0.7–1.4)
Adverse clinical symptoms0.7
 Yes0.9 (0.7–1.3)
 NoReference
Adverse biological parameters0.1
 Yes0.9 (0.7–1.3)
 NoReference
ECOG-PS0.9
 0Reference
 ≥10.9 (0.7–1.4)
Disease characteristicOR (95% CI)P-value
Lymphoma0.2
 HodgkinReference
 Non-Hodgkin1.2 (0.9–1.7)
Ann-Arbor stage0.9
 I–II (localized)Reference
 III–IV (disseminated)1.0 (0.7–1.4)
Adverse clinical symptoms0.7
 Yes0.9 (0.7–1.3)
 NoReference
Adverse biological parameters0.1
 Yes0.9 (0.7–1.3)
 NoReference
ECOG-PS0.9
 0Reference
 ≥10.9 (0.7–1.4)

COH, ovarian stimulation; MII, metaphase II; OR, odds ratio; ECOG-PS, Eastern Cooperative Oncology Group Performance Status.

All results were adjusted for POSEIDON criteria before ovarian stimulation (Groups 3 and 4).

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