Predictive factors of impaired response to COH (≤ 9 MII oocytes) for fertility preservation before lymphoma treatment.
Disease characteristic . | OR (95% CI) . | P-value . |
---|---|---|
Lymphoma | 0.2 | |
Hodgkin | Reference | |
Non-Hodgkin | 1.2 (0.9–1.7) | |
Ann-Arbor stage | 0.9 | |
I–II (localized) | Reference | |
III–IV (disseminated) | 1.0 (0.7–1.4) | |
Adverse clinical symptoms | 0.7 | |
Yes | 0.9 (0.7–1.3) | |
No | Reference | |
Adverse biological parameters | 0.1 | |
Yes | 0.9 (0.7–1.3) | |
No | Reference | |
ECOG-PS | 0.9 | |
0 | Reference | |
≥1 | 0.9 (0.7–1.4) |
Disease characteristic . | OR (95% CI) . | P-value . |
---|---|---|
Lymphoma | 0.2 | |
Hodgkin | Reference | |
Non-Hodgkin | 1.2 (0.9–1.7) | |
Ann-Arbor stage | 0.9 | |
I–II (localized) | Reference | |
III–IV (disseminated) | 1.0 (0.7–1.4) | |
Adverse clinical symptoms | 0.7 | |
Yes | 0.9 (0.7–1.3) | |
No | Reference | |
Adverse biological parameters | 0.1 | |
Yes | 0.9 (0.7–1.3) | |
No | Reference | |
ECOG-PS | 0.9 | |
0 | Reference | |
≥1 | 0.9 (0.7–1.4) |
COH, ovarian stimulation; MII, metaphase II; OR, odds ratio; ECOG-PS, Eastern Cooperative Oncology Group Performance Status.
All results were adjusted for POSEIDON criteria before ovarian stimulation (Groups 3 and 4).
Predictive factors of impaired response to COH (≤ 9 MII oocytes) for fertility preservation before lymphoma treatment.
Disease characteristic . | OR (95% CI) . | P-value . |
---|---|---|
Lymphoma | 0.2 | |
Hodgkin | Reference | |
Non-Hodgkin | 1.2 (0.9–1.7) | |
Ann-Arbor stage | 0.9 | |
I–II (localized) | Reference | |
III–IV (disseminated) | 1.0 (0.7–1.4) | |
Adverse clinical symptoms | 0.7 | |
Yes | 0.9 (0.7–1.3) | |
No | Reference | |
Adverse biological parameters | 0.1 | |
Yes | 0.9 (0.7–1.3) | |
No | Reference | |
ECOG-PS | 0.9 | |
0 | Reference | |
≥1 | 0.9 (0.7–1.4) |
Disease characteristic . | OR (95% CI) . | P-value . |
---|---|---|
Lymphoma | 0.2 | |
Hodgkin | Reference | |
Non-Hodgkin | 1.2 (0.9–1.7) | |
Ann-Arbor stage | 0.9 | |
I–II (localized) | Reference | |
III–IV (disseminated) | 1.0 (0.7–1.4) | |
Adverse clinical symptoms | 0.7 | |
Yes | 0.9 (0.7–1.3) | |
No | Reference | |
Adverse biological parameters | 0.1 | |
Yes | 0.9 (0.7–1.3) | |
No | Reference | |
ECOG-PS | 0.9 | |
0 | Reference | |
≥1 | 0.9 (0.7–1.4) |
COH, ovarian stimulation; MII, metaphase II; OR, odds ratio; ECOG-PS, Eastern Cooperative Oncology Group Performance Status.
All results were adjusted for POSEIDON criteria before ovarian stimulation (Groups 3 and 4).
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