Table 2.

Univariate meta-analysis of the risk factor for CDI in IBD flare.

Population characteristicsNo of studiesOR (95% Confidence interval)P-valueR2, %
Mean age (per 1-y increase from mean of 34 y)171.06 (0.99– 1.13).091.2
Proportion exposed to antibiotics (per 5-percentage point increase)201.01 (0.92–1.11).790.0
Proportion PPI use (per 5-percentage point increase)80.83 (0.68–1.01).0626.3
Proportion male (per 5-percentage point increase)251.18 (1.00 –1.40).05649
White (per 5- percentage point increase) US and Canada studies)50.87 (0.60–1.27).360.0
Year of study (per 5- y increase)281.19 (0.78–1.81).450.0
Proportion ulcerative colitis (per 5-percentage point increase)281.02 (0.95–1.10).610.0
Method of test used.0417
PCR44.70 (01.39–15.90)
Multiple methods30.89 (0.36 –2.19)
EIA16Reference (EIA)
Population characteristicsNo of studiesOR (95% Confidence interval)P-valueR2, %
Mean age (per 1-y increase from mean of 34 y)171.06 (0.99– 1.13).091.2
Proportion exposed to antibiotics (per 5-percentage point increase)201.01 (0.92–1.11).790.0
Proportion PPI use (per 5-percentage point increase)80.83 (0.68–1.01).0626.3
Proportion male (per 5-percentage point increase)251.18 (1.00 –1.40).05649
White (per 5- percentage point increase) US and Canada studies)50.87 (0.60–1.27).360.0
Year of study (per 5- y increase)281.19 (0.78–1.81).450.0
Proportion ulcerative colitis (per 5-percentage point increase)281.02 (0.95–1.10).610.0
Method of test used.0417
PCR44.70 (01.39–15.90)
Multiple methods30.89 (0.36 –2.19)
EIA16Reference (EIA)
Table 2.

Univariate meta-analysis of the risk factor for CDI in IBD flare.

Population characteristicsNo of studiesOR (95% Confidence interval)P-valueR2, %
Mean age (per 1-y increase from mean of 34 y)171.06 (0.99– 1.13).091.2
Proportion exposed to antibiotics (per 5-percentage point increase)201.01 (0.92–1.11).790.0
Proportion PPI use (per 5-percentage point increase)80.83 (0.68–1.01).0626.3
Proportion male (per 5-percentage point increase)251.18 (1.00 –1.40).05649
White (per 5- percentage point increase) US and Canada studies)50.87 (0.60–1.27).360.0
Year of study (per 5- y increase)281.19 (0.78–1.81).450.0
Proportion ulcerative colitis (per 5-percentage point increase)281.02 (0.95–1.10).610.0
Method of test used.0417
PCR44.70 (01.39–15.90)
Multiple methods30.89 (0.36 –2.19)
EIA16Reference (EIA)
Population characteristicsNo of studiesOR (95% Confidence interval)P-valueR2, %
Mean age (per 1-y increase from mean of 34 y)171.06 (0.99– 1.13).091.2
Proportion exposed to antibiotics (per 5-percentage point increase)201.01 (0.92–1.11).790.0
Proportion PPI use (per 5-percentage point increase)80.83 (0.68–1.01).0626.3
Proportion male (per 5-percentage point increase)251.18 (1.00 –1.40).05649
White (per 5- percentage point increase) US and Canada studies)50.87 (0.60–1.27).360.0
Year of study (per 5- y increase)281.19 (0.78–1.81).450.0
Proportion ulcerative colitis (per 5-percentage point increase)281.02 (0.95–1.10).610.0
Method of test used.0417
PCR44.70 (01.39–15.90)
Multiple methods30.89 (0.36 –2.19)
EIA16Reference (EIA)
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