Diagnostic performance of Coronary Magnetic Resonance Angiography (CMRA) and Coronary Computed Tomography Angiography (CCTA) using a threshold of CAD-RADS ≥4 (severe stenosis) to determine threshold to invasive coronary angiography and coronary revascularization
| Referral to invasive coronary angiography (CAD-RADS ≥ 4) . | ||||||
|---|---|---|---|---|---|---|
| . | Sensitivity . | Specificity . | PPV . | NPV . | Diagnostic accuracy . | AUC . |
| CMRA | 0.76 (0.55–0.91) | 0.74* (0.62–0.84) | 0.51 (0.34–0.68) | 0.90 (0.79–0.96) | 0.75 (0.65–0.83) | 0.75 (0.66–0.84) |
| CCTA | 0.56 (0.35–0.76) | 0.89* (0.79–0.95) | 0.64 (0.41–0.83) | 0.85 (0.75–0.92) | 0.80 (0.71–0.88) | 0.70 (0.58–0.82) |
| Referral to invasive coronary angiography (CAD-RADS ≥ 4) . | ||||||
|---|---|---|---|---|---|---|
| . | Sensitivity . | Specificity . | PPV . | NPV . | Diagnostic accuracy . | AUC . |
| CMRA | 0.76 (0.55–0.91) | 0.74* (0.62–0.84) | 0.51 (0.34–0.68) | 0.90 (0.79–0.96) | 0.75 (0.65–0.83) | 0.75 (0.66–0.84) |
| CCTA | 0.56 (0.35–0.76) | 0.89* (0.79–0.95) | 0.64 (0.41–0.83) | 0.85 (0.75–0.92) | 0.80 (0.71–0.88) | 0.70 (0.58–0.82) |
| Undergo coronary revascularization (CAD-RADS ≥ 4) . | ||||||
|---|---|---|---|---|---|---|
| . | Sensitivity . | Specificity . | PPV . | NPV . | Diagnostic accuracy . | AUC . |
| CMRA | 0.75 (0.48–0.93) | 0.68* (0.57–0.78) | 0.32 (0.18–0.50) | 0.93 (0.83–0.98) | 0.69 (0.59–0.79) | 0.72 (0.61–0.84) |
| CCTA | 0.62 (0.35–0.85) | 0.85* (0.75–0.92) | 0.45 (0.24–0.68) | 0.92 (0.83–0.97) | 0.81 (0.72–0.88) | 0.74 (0.67–0.80) |
| Undergo coronary revascularization (CAD-RADS ≥ 4) . | ||||||
|---|---|---|---|---|---|---|
| . | Sensitivity . | Specificity . | PPV . | NPV . | Diagnostic accuracy . | AUC . |
| CMRA | 0.75 (0.48–0.93) | 0.68* (0.57–0.78) | 0.32 (0.18–0.50) | 0.93 (0.83–0.98) | 0.69 (0.59–0.79) | 0.72 (0.61–0.84) |
| CCTA | 0.62 (0.35–0.85) | 0.85* (0.75–0.92) | 0.45 (0.24–0.68) | 0.92 (0.83–0.97) | 0.81 (0.72–0.88) | 0.74 (0.67–0.80) |
CAD-RADS, Coronary Artery Disease –Reporting and Data System; CCTA, Coronary Computed Tomography Angiography; CMRA, Coronary Magnetic Resonance Angiography; NPV, Negative Predictive Value; PPV, Positive Predictive Value. * Indicates a statistically significant difference.
Diagnostic performance of Coronary Magnetic Resonance Angiography (CMRA) and Coronary Computed Tomography Angiography (CCTA) using a threshold of CAD-RADS ≥4 (severe stenosis) to determine threshold to invasive coronary angiography and coronary revascularization
| Referral to invasive coronary angiography (CAD-RADS ≥ 4) . | ||||||
|---|---|---|---|---|---|---|
| . | Sensitivity . | Specificity . | PPV . | NPV . | Diagnostic accuracy . | AUC . |
| CMRA | 0.76 (0.55–0.91) | 0.74* (0.62–0.84) | 0.51 (0.34–0.68) | 0.90 (0.79–0.96) | 0.75 (0.65–0.83) | 0.75 (0.66–0.84) |
| CCTA | 0.56 (0.35–0.76) | 0.89* (0.79–0.95) | 0.64 (0.41–0.83) | 0.85 (0.75–0.92) | 0.80 (0.71–0.88) | 0.70 (0.58–0.82) |
| Referral to invasive coronary angiography (CAD-RADS ≥ 4) . | ||||||
|---|---|---|---|---|---|---|
| . | Sensitivity . | Specificity . | PPV . | NPV . | Diagnostic accuracy . | AUC . |
| CMRA | 0.76 (0.55–0.91) | 0.74* (0.62–0.84) | 0.51 (0.34–0.68) | 0.90 (0.79–0.96) | 0.75 (0.65–0.83) | 0.75 (0.66–0.84) |
| CCTA | 0.56 (0.35–0.76) | 0.89* (0.79–0.95) | 0.64 (0.41–0.83) | 0.85 (0.75–0.92) | 0.80 (0.71–0.88) | 0.70 (0.58–0.82) |
| Undergo coronary revascularization (CAD-RADS ≥ 4) . | ||||||
|---|---|---|---|---|---|---|
| . | Sensitivity . | Specificity . | PPV . | NPV . | Diagnostic accuracy . | AUC . |
| CMRA | 0.75 (0.48–0.93) | 0.68* (0.57–0.78) | 0.32 (0.18–0.50) | 0.93 (0.83–0.98) | 0.69 (0.59–0.79) | 0.72 (0.61–0.84) |
| CCTA | 0.62 (0.35–0.85) | 0.85* (0.75–0.92) | 0.45 (0.24–0.68) | 0.92 (0.83–0.97) | 0.81 (0.72–0.88) | 0.74 (0.67–0.80) |
| Undergo coronary revascularization (CAD-RADS ≥ 4) . | ||||||
|---|---|---|---|---|---|---|
| . | Sensitivity . | Specificity . | PPV . | NPV . | Diagnostic accuracy . | AUC . |
| CMRA | 0.75 (0.48–0.93) | 0.68* (0.57–0.78) | 0.32 (0.18–0.50) | 0.93 (0.83–0.98) | 0.69 (0.59–0.79) | 0.72 (0.61–0.84) |
| CCTA | 0.62 (0.35–0.85) | 0.85* (0.75–0.92) | 0.45 (0.24–0.68) | 0.92 (0.83–0.97) | 0.81 (0.72–0.88) | 0.74 (0.67–0.80) |
CAD-RADS, Coronary Artery Disease –Reporting and Data System; CCTA, Coronary Computed Tomography Angiography; CMRA, Coronary Magnetic Resonance Angiography; NPV, Negative Predictive Value; PPV, Positive Predictive Value. * Indicates a statistically significant difference.
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