| Vascular death | Sudden death: unexpected cardiac death occurring within 1 h after onset of symptoms, or within 24 h given convincing circumstantial evidence |
| Death from ischaemic stroke | |
| Death from intracerebral haemorrhage (haemorrhage on CT-scan) | |
| Death from congestive heart failure | |
| Death from myocardial infarction | |
| Death from rupture of abdominal aortic aneurysm | |
| Vascular death from other cause, such as sepsis following stent placement | |
| Ischaemic stroke | Definite: relevant clinical features that have caused an increase in impairment of at least one grade on the modified Rankin scale, accompanied by a fresh ischaemic infarction on a repeat brain-scan |
| Probable: clinical features that have caused an increase in impairment of at least one grade on the modified Rankin scale; without a fresh ischaemic infarction on a repeat brain-scan | |
| Myocardial infarction | Fatal or non-fatal myocardial infarction: at least two of the following criteria |
| (i) chest pain for at least 20 min, not disappearing after administration of nitrates | |
| (ii) ST-elevation >1 mm in two following leads or a left bundle branch block on the electrocardiogram | |
| (iii) Creatinine kinase (CK) elevation of at least two times the normal value of CK and a myocardial band-fraction >5% of the total CK | |
| All-cause mortality | Death from any cause (both vascular and non-vascular causes) |
| Vascular death | Sudden death: unexpected cardiac death occurring within 1 h after onset of symptoms, or within 24 h given convincing circumstantial evidence |
| Death from ischaemic stroke | |
| Death from intracerebral haemorrhage (haemorrhage on CT-scan) | |
| Death from congestive heart failure | |
| Death from myocardial infarction | |
| Death from rupture of abdominal aortic aneurysm | |
| Vascular death from other cause, such as sepsis following stent placement | |
| Ischaemic stroke | Definite: relevant clinical features that have caused an increase in impairment of at least one grade on the modified Rankin scale, accompanied by a fresh ischaemic infarction on a repeat brain-scan |
| Probable: clinical features that have caused an increase in impairment of at least one grade on the modified Rankin scale; without a fresh ischaemic infarction on a repeat brain-scan | |
| Myocardial infarction | Fatal or non-fatal myocardial infarction: at least two of the following criteria |
| (i) chest pain for at least 20 min, not disappearing after administration of nitrates | |
| (ii) ST-elevation >1 mm in two following leads or a left bundle branch block on the electrocardiogram | |
| (iii) Creatinine kinase (CK) elevation of at least two times the normal value of CK and a myocardial band-fraction >5% of the total CK | |
| All-cause mortality | Death from any cause (both vascular and non-vascular causes) |
| Vascular death | Sudden death: unexpected cardiac death occurring within 1 h after onset of symptoms, or within 24 h given convincing circumstantial evidence |
| Death from ischaemic stroke | |
| Death from intracerebral haemorrhage (haemorrhage on CT-scan) | |
| Death from congestive heart failure | |
| Death from myocardial infarction | |
| Death from rupture of abdominal aortic aneurysm | |
| Vascular death from other cause, such as sepsis following stent placement | |
| Ischaemic stroke | Definite: relevant clinical features that have caused an increase in impairment of at least one grade on the modified Rankin scale, accompanied by a fresh ischaemic infarction on a repeat brain-scan |
| Probable: clinical features that have caused an increase in impairment of at least one grade on the modified Rankin scale; without a fresh ischaemic infarction on a repeat brain-scan | |
| Myocardial infarction | Fatal or non-fatal myocardial infarction: at least two of the following criteria |
| (i) chest pain for at least 20 min, not disappearing after administration of nitrates | |
| (ii) ST-elevation >1 mm in two following leads or a left bundle branch block on the electrocardiogram | |
| (iii) Creatinine kinase (CK) elevation of at least two times the normal value of CK and a myocardial band-fraction >5% of the total CK | |
| All-cause mortality | Death from any cause (both vascular and non-vascular causes) |
| Vascular death | Sudden death: unexpected cardiac death occurring within 1 h after onset of symptoms, or within 24 h given convincing circumstantial evidence |
| Death from ischaemic stroke | |
| Death from intracerebral haemorrhage (haemorrhage on CT-scan) | |
| Death from congestive heart failure | |
| Death from myocardial infarction | |
| Death from rupture of abdominal aortic aneurysm | |
| Vascular death from other cause, such as sepsis following stent placement | |
| Ischaemic stroke | Definite: relevant clinical features that have caused an increase in impairment of at least one grade on the modified Rankin scale, accompanied by a fresh ischaemic infarction on a repeat brain-scan |
| Probable: clinical features that have caused an increase in impairment of at least one grade on the modified Rankin scale; without a fresh ischaemic infarction on a repeat brain-scan | |
| Myocardial infarction | Fatal or non-fatal myocardial infarction: at least two of the following criteria |
| (i) chest pain for at least 20 min, not disappearing after administration of nitrates | |
| (ii) ST-elevation >1 mm in two following leads or a left bundle branch block on the electrocardiogram | |
| (iii) Creatinine kinase (CK) elevation of at least two times the normal value of CK and a myocardial band-fraction >5% of the total CK | |
| All-cause mortality | Death from any cause (both vascular and non-vascular causes) |
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