Energy Expenditure and Its Components and Insulin Sensitivity (M/I) by the Euglycemic Hyperinsulinemic Clamp
| . | Diet . | BPD . | ||
|---|---|---|---|---|
| Pretreatment . | Posttreatment . | Pretreatment . | Posttreatment . | |
| Subjects (n) | 9 | 9 | 6 | 6 |
| REE (kcal/24 h) | 2586.9 ± 540.2 | 2828.3 ± 619.1 | 2534.7 ± 589.3 | 2264.4 ± 575.0 |
| TEE (kcal/24 h) | 3394.5 ± 670.1 | 3044.4 ± 658.2 | 3461.9 ± 784.4 | 3251.0 ± 774.2 |
| PA (a.m.u.) | 3.65 ± 0.36 | 4.39 ± 0.34 | 3.35 ± 0.33 | 4.65 ± 0.66a |
| Exercise (kcal/24 h) | 7977.5 ± 881.6 | 8040.5 ± 1122.2 | 8344.3 ± 578.1 | 9701.4 ± 544.1a |
| Exercise (kcal · 30 min) | 166.2 ± 18.4 | 167.5 ± 23.4 | 173.8 ± 11.9 | 202.1 ± 11.3a |
| DIT (% of caloric intake) | 11.5 ± 2.9 | 10.0 ± 3.8 | 11.0 ± 2.1 | 19.9 ± 1.1a |
| M (μmol/kg/min) | 51.63 ± 6.04 | 52.49 ± 5.79 | 50.56 ± 6.02 | 92.27 ± 9.43b |
| Clamp insulin (pmol/L) | 581.05 ± 56.23 | 530.60 ± 51.47 | 505.21 ± 50.49 | 512.03 ± 76.62 |
| M/I (μmol/kg/min/pM) | 0.089 ± 0.012 | 0.108 ± 0.017 | 0.101 ± 0.012 | 0.204 ± 0.033a |
| . | Diet . | BPD . | ||
|---|---|---|---|---|
| Pretreatment . | Posttreatment . | Pretreatment . | Posttreatment . | |
| Subjects (n) | 9 | 9 | 6 | 6 |
| REE (kcal/24 h) | 2586.9 ± 540.2 | 2828.3 ± 619.1 | 2534.7 ± 589.3 | 2264.4 ± 575.0 |
| TEE (kcal/24 h) | 3394.5 ± 670.1 | 3044.4 ± 658.2 | 3461.9 ± 784.4 | 3251.0 ± 774.2 |
| PA (a.m.u.) | 3.65 ± 0.36 | 4.39 ± 0.34 | 3.35 ± 0.33 | 4.65 ± 0.66a |
| Exercise (kcal/24 h) | 7977.5 ± 881.6 | 8040.5 ± 1122.2 | 8344.3 ± 578.1 | 9701.4 ± 544.1a |
| Exercise (kcal · 30 min) | 166.2 ± 18.4 | 167.5 ± 23.4 | 173.8 ± 11.9 | 202.1 ± 11.3a |
| DIT (% of caloric intake) | 11.5 ± 2.9 | 10.0 ± 3.8 | 11.0 ± 2.1 | 19.9 ± 1.1a |
| M (μmol/kg/min) | 51.63 ± 6.04 | 52.49 ± 5.79 | 50.56 ± 6.02 | 92.27 ± 9.43b |
| Clamp insulin (pmol/L) | 581.05 ± 56.23 | 530.60 ± 51.47 | 505.21 ± 50.49 | 512.03 ± 76.62 |
| M/I (μmol/kg/min/pM) | 0.089 ± 0.012 | 0.108 ± 0.017 | 0.101 ± 0.012 | 0.204 ± 0.033a |
The REE, the total energy expenditure (TEE), the PA, and the energy expenditure during the physical exercise (Exercise) on the treadmill were measured in the calorimetric chamber. The diet-induced thermogenesis (DIT) was computed by the model, as detailed in the Appendix. M is the insulin-induced glucose uptake during the euglycemic hyperinsulinemic clamp and M/I is the M normalized by the plasma insulin concentration averaged during the last 40 minutes of the clamp (4 time point mean).
P < .05 and
P < .01 between posttreatment diet vs BPD groups.
Energy Expenditure and Its Components and Insulin Sensitivity (M/I) by the Euglycemic Hyperinsulinemic Clamp
| . | Diet . | BPD . | ||
|---|---|---|---|---|
| Pretreatment . | Posttreatment . | Pretreatment . | Posttreatment . | |
| Subjects (n) | 9 | 9 | 6 | 6 |
| REE (kcal/24 h) | 2586.9 ± 540.2 | 2828.3 ± 619.1 | 2534.7 ± 589.3 | 2264.4 ± 575.0 |
| TEE (kcal/24 h) | 3394.5 ± 670.1 | 3044.4 ± 658.2 | 3461.9 ± 784.4 | 3251.0 ± 774.2 |
| PA (a.m.u.) | 3.65 ± 0.36 | 4.39 ± 0.34 | 3.35 ± 0.33 | 4.65 ± 0.66a |
| Exercise (kcal/24 h) | 7977.5 ± 881.6 | 8040.5 ± 1122.2 | 8344.3 ± 578.1 | 9701.4 ± 544.1a |
| Exercise (kcal · 30 min) | 166.2 ± 18.4 | 167.5 ± 23.4 | 173.8 ± 11.9 | 202.1 ± 11.3a |
| DIT (% of caloric intake) | 11.5 ± 2.9 | 10.0 ± 3.8 | 11.0 ± 2.1 | 19.9 ± 1.1a |
| M (μmol/kg/min) | 51.63 ± 6.04 | 52.49 ± 5.79 | 50.56 ± 6.02 | 92.27 ± 9.43b |
| Clamp insulin (pmol/L) | 581.05 ± 56.23 | 530.60 ± 51.47 | 505.21 ± 50.49 | 512.03 ± 76.62 |
| M/I (μmol/kg/min/pM) | 0.089 ± 0.012 | 0.108 ± 0.017 | 0.101 ± 0.012 | 0.204 ± 0.033a |
| . | Diet . | BPD . | ||
|---|---|---|---|---|
| Pretreatment . | Posttreatment . | Pretreatment . | Posttreatment . | |
| Subjects (n) | 9 | 9 | 6 | 6 |
| REE (kcal/24 h) | 2586.9 ± 540.2 | 2828.3 ± 619.1 | 2534.7 ± 589.3 | 2264.4 ± 575.0 |
| TEE (kcal/24 h) | 3394.5 ± 670.1 | 3044.4 ± 658.2 | 3461.9 ± 784.4 | 3251.0 ± 774.2 |
| PA (a.m.u.) | 3.65 ± 0.36 | 4.39 ± 0.34 | 3.35 ± 0.33 | 4.65 ± 0.66a |
| Exercise (kcal/24 h) | 7977.5 ± 881.6 | 8040.5 ± 1122.2 | 8344.3 ± 578.1 | 9701.4 ± 544.1a |
| Exercise (kcal · 30 min) | 166.2 ± 18.4 | 167.5 ± 23.4 | 173.8 ± 11.9 | 202.1 ± 11.3a |
| DIT (% of caloric intake) | 11.5 ± 2.9 | 10.0 ± 3.8 | 11.0 ± 2.1 | 19.9 ± 1.1a |
| M (μmol/kg/min) | 51.63 ± 6.04 | 52.49 ± 5.79 | 50.56 ± 6.02 | 92.27 ± 9.43b |
| Clamp insulin (pmol/L) | 581.05 ± 56.23 | 530.60 ± 51.47 | 505.21 ± 50.49 | 512.03 ± 76.62 |
| M/I (μmol/kg/min/pM) | 0.089 ± 0.012 | 0.108 ± 0.017 | 0.101 ± 0.012 | 0.204 ± 0.033a |
The REE, the total energy expenditure (TEE), the PA, and the energy expenditure during the physical exercise (Exercise) on the treadmill were measured in the calorimetric chamber. The diet-induced thermogenesis (DIT) was computed by the model, as detailed in the Appendix. M is the insulin-induced glucose uptake during the euglycemic hyperinsulinemic clamp and M/I is the M normalized by the plasma insulin concentration averaged during the last 40 minutes of the clamp (4 time point mean).
P < .05 and
P < .01 between posttreatment diet vs BPD groups.
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