Structure and activity of LQB-118 against intracellular amastigotes. (a) Schematic diagram of LQB-118 design. (b) Murine peritoneal macrophages were infected with L. amazonensis and incubated with LQB-118 at various concentrations (1.25–10 μM). After 72 h, the slides were stained, and the infection index was established by counting at least 100 macrophages under a light microscope. Mean ± SD; n = 3; *P < 0.001.