Group differences in thalamo-cortical networks. Nine cortical networks from group-level ICAs (first and third row) and thalamic clusters that differed between groups for each resting-sate network (second and fourth row) are depicted. (i) Motor network; patients showed lower thalamo-cortical connectivity in the mediodorsal nucleus and nuclei from the anterior group and higher thalamo-cortical connectivity in nuclei from the lateral group. (ii) Visual network; patients showed lower thalamo-cortical connectivity in the pulvinar, ventral lateral, ventral posterior, mediodorsal and lateral posterior nuclei. (iii) Auditory network; patients showed lower thalamo-cortical connectivity in the lateral and medial nuclei, including the lateral dorsal and mediodorsal nuclei. (iv) DMN; patients showed lower thalamo-cortical connectivity in the pulvinar and higher thalamo-cortical connectivity in the mediodorsal nucleus. (v) Posterior DMN; patients showed lower thalamo-cortical connectivity in the lateral nuclei and in the pulvinar. (vi) Salience network; patients showed lower thalamo-cortical connectivity in the mediodorsal nucleus and the pulvinar. (vii) Dorsal attention network; patients showed lower thalamo-cortical connectivity in the pulvinar, and mediodorsal nucleus and higher thalamo-cortical connectivity in the anteroventral nucleus. (viii) Right and left executive network; patients showed lower thalamo-cortical connectivity in the mediodorsal nucleus, pulvinar and in the lateral group. (ix) Left executive network: patients showed higher thalamo-cortical connectivity in the pulvinar. Notes. DMN, default mode network; L-EF, left executive network; R-EF, right executive network. The right side of the brain is on the right side of the image. All sub-regions of the thalamus are thresholded at FDR-corrected Pā=ā0.05. Only FDR-corrected voxels are depicted in the Figure.
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